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Protein

Translation initiation factor IF-1 1

Gene

infA1

Organism
Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.UniRule annotation

GO - Molecular functioni

Keywordsi

Molecular functionInitiation factor, RNA-binding, rRNA-binding
Biological processProtein biosynthesis

Names & Taxonomyi

Protein namesi
Recommended name:
Translation initiation factor IF-1 1UniRule annotation
Gene namesi
Name:infA1UniRule annotation
Ordered Locus Names:Bcep18194_B1450
OrganismiBurkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383)
Taxonomic identifieri482957 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaBurkholderialesBurkholderiaceaeBurkholderiaBurkholderia cepacia complex
Proteomesi
  • UP000002705 Componenti: Chromosome 2

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002637751 – 87Translation initiation factor IF-1 1Add BLAST87

Interactioni

Subunit structurei

Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.UniRule annotation

Structurei

3D structure databases

ProteinModelPortaliQ396P7
SMRiQ396P7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 72S1-likeUniRule annotationAdd BLAST72

Sequence similaritiesi

Belongs to the IF-1 family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000221323
KOiK02518
OMAiGKMRKNH
OrthoDBiPOG091H019C

Family and domain databases

CDDicd04451 S1_IF1, 1 hit
HAMAPiMF_00075 IF_1, 1 hit
InterProiView protein in InterPro
IPR012340 NA-bd_OB-fold
IPR006196 RNA-binding_domain_S1_IF1
IPR004368 TIF_IF1
PANTHERiPTHR33370 PTHR33370, 1 hit
PfamiView protein in Pfam
PF01176 eIF-1a, 1 hit
SUPFAMiSSF50249 SSF50249, 1 hit
TIGRFAMsiTIGR00008 infA, 1 hit
PROSITEiView protein in PROSITE
PS50832 S1_IF1_TYPE, 1 hit

Sequencei

Sequence statusi: Complete.

Q396P7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKEELLELD GIVDEVLPDS KYRVTLENGV VVGAYASGRM RKNHIRILAG
60 70 80
DRVTLELSVY DLTKGRINFR HKDANSPRPP RTGQPRR
Length:87
Mass (Da):9,857
Last modified:November 22, 2005 - v1
Checksum:iD9B2F6EA4E632720
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000152 Genomic DNA Translation: ABB11564.1
RefSeqiWP_011355053.1, NC_007511.1

Genome annotation databases

EnsemblBacteriaiABB11564; ABB11564; Bcep18194_B1450
KEGGibur:Bcep18194_B1450
PATRICifig|482957.22.peg.5144

Similar proteinsi

Entry informationi

Entry nameiIF11_BURL3
AccessioniPrimary (citable) accession number: Q396P7
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 12, 2006
Last sequence update: November 22, 2005
Last modified: March 28, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome
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Main funding by: National Institutes of Health