Q39617 (POR_CHLRE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protochlorophyllide reductase, chloroplastic
Short name=PCR
EC=1.3.1.33

Alternative name(s):
NADPH-protochlorophyllide oxidoreductase
Short name=POR

Gene names

Name:	PORA
Synonyms:	LPCR-1

Organism

Chlamydomonas reinhardtii (Chlamydomonas smithii)

Taxonomic identifier

3055 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Chlorophyta › Chlorophyceae › Chlamydomonadales › Chlamydomonadaceae › Chlamydomonas

Protein attributes

Sequence length	397 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Phototransformation of protochlorophyllide (Pchlide) to chlorophyllide (Chlide).
Catalytic activity	Chlorophyllide a + NADP+ = protochlorophyllide + NADPH.
Pathway	Porphyrin biosynthesis; chlorophyll biosynthesis.
Subcellular location	Plastid › chloroplast.
Sequence similarities	Belongs to the short-chain dehydrogenases/reductases (SDR) family. POR subfamily.

Ontologies

Keywords
Biological process	Chlorophyll biosynthesis Photosynthesis
Cellular component	Chloroplast Plastid
Domain	Transit peptide
Ligand	NADP
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	chlorophyll biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW photosynthesis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	nucleotide binding Inferred from electronic annotation. Source: InterPro protochlorophyllide reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Transit peptide	1 – 57	57	Chloroplast Potential
	Chain	58 – 397	340	Protochlorophyllide reductase, chloroplastic		PRO_0000023290

Sequences

	Sequence		Length	Mass (Da)
	Q39617 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 4CEF08F15545754D	FASTA	397	41,871
	10 20 30 40 50 60 MALTMSAKSV SARAQVSSKA QAAPAVAVSG RTSSRVMPAP ALAARSSVAR TPLVVCAATA 70 80 90 100 110 120 TAPSPSLADK FKPNAIARVP ATQQKQTAII TGASSGLGLN AAKALAATGE WHVVMACRDF 130 140 150 160 170 180 LKAEQAAKKV GMPAGSYSIL HLDLSSLESV RQFVQNFKAS GRRLDALVCN AAVYLPTAKE 190 200 210 220 230 240 PRFTADGFEL SVGTNHLGHF LLTNLLLDDL KNAPNKQPRC IIVGSITGNT NTLAGNVPPK 250 260 270 280 290 300 ANLGDLSGLA AGVPAANPMM DGQEFNGAKA YKDSKVACMM TVRQMHQRFH DATGITFASL 310 320 330 340 350 360 YPGCIAETGL FREHVPLFKT LFPPFQKYIT KGYVSEEEAG RRLAAVISDP KLNKSGAYWS 370 380 390 WSSTTGSFDN QVSEEVADDS KASKLWDISA KLVGLSA

References

[1]	"The pc-1 phenotype of Chlamydomonas reinhardtii results from a deletion mutation in the nuclear gene for NADPH:protochlorophyllide oxidoreductase." Li J., Timko M.P. Plant Mol. Biol. 30:15-37(1996) [PubMed: 8616232] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 137c / CC-125.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U36752 Genomic DNA. Translation: AAB04951.1.
PIR	S71468.
RefSeq	XP_001689464.1. XM_001689412.1.
UniGene	Cre.4474.
3D structure databases
ProteinModelPortal	Q39617.
ModBase	Search...
Protein-protein interaction databases
STRING	Q39617.
Proteomic databases
PRIDE	Q39617.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblPlants	EDP09202; EDP09202; CHLREDRAFT_136589.
GeneID	5715107.
KEGG	cre:CHLREDRAFT_136589.
Phylogenomic databases
PhylomeDB	Q39617.
ProtClustDB	PLN00015.
Enzyme and pathway databases
BioCyc	CHLAMY:CHLREDRAFT_136589-MONOMER.
Family and domain databases
InterPro	IPR002198. DH_sc/Rdtase_SDR. IPR002347. Glc/ribitol_DH. IPR016040. NAD(P)-bd_dom. IPR005979. Prochl_reduct. [Graphical view]
Gene3D	G3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
KO	K00218.
PANTHER	PTHR24316:SF100. PTHR24316:SF100. 1 hit.
Pfam	PF00106. adh_short. 1 hit. [Graphical view]
PRINTS	PR00081. GDHRDH.
TIGRFAMs	TIGR01289. LPOR. 1 hit.
ProtoNet	Search...

Entry information

Entry name

POR_CHLRE

Accession

Primary (citable) accession number: Q39617

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 1, 2000
Last sequence update:	November 1, 1996
Last modified:	December 14, 2011
This is version 75 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program