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Protein

Tubulin gamma chain

Gene

TUBG

Organism
Chlamydomonas reinhardtii (Chlamydomonas smithii)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Tubulin is the major constituent of microtubules. The gamma chain is found at microtubule organizing centers (MTOC) such as the spindle poles or the centrosome, suggesting that it is involved in the minus-end nucleation of microtubule assembly.

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi142 – 148GTPSequence analysis7

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

GTP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Tubulin gamma chain
Alternative name(s):
Gamma-tubulin
Gene namesi
Name:TUBG
Synonyms:TBG1, TUBC
OrganismiChlamydomonas reinhardtii (Chlamydomonas smithii)
Taxonomic identifieri3055 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeChlorophytaChlorophyceaeChlamydomonadalesChlamydomonadaceaeChlamydomonas

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm, Cytoskeleton, Microtubule

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000484511 – 468Tubulin gamma chainAdd BLAST468

Proteomic databases

PaxDbiQ39582.
PRIDEiQ39582.

Interactioni

Protein-protein interaction databases

STRINGi3055.EDP05025.

Structurei

3D structure databases

ProteinModelPortaliQ39582.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the tubulin family.Curated

Phylogenomic databases

eggNOGiKOG1374. Eukaryota.
COG5023. LUCA.
KOiK10389.
OMAiANEYAAC.

Family and domain databases

CDDicd02188. gamma_tubulin. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
InterProiIPR002454. Gamma_tubulin.
IPR008280. Tub_FtsZ_C.
IPR000217. Tubulin.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR017975. Tubulin_CS.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PANTHERiPTHR11588. PTHR11588. 1 hit.
PTHR11588:SF7. PTHR11588:SF7. 1 hit.
PfamiPF00091. Tubulin. 1 hit.
PF03953. Tubulin_C. 1 hit.
[Graphical view]
PRINTSiPR01164. GAMMATUBULIN.
PR01161. TUBULIN.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
PROSITEiPS00227. TUBULIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q39582-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPREIINLQV GQCGNQVGSE FWRKLCQEHG IAKDGRLEDF ATLGGDRKDV
60 70 80 90 100
FFYQADDEQY IPRAILLDLE PRVINGIQTS DLRNLFNPEN IFISKEGGGA
110 120 130 140 150
GNNWASGYTQ GEAVQETLLD MIDREAEYCD SLEGFNMCHS IAGGTGSGMG
160 170 180 190 200
SYMLELISDR YSKKLIQTYS VFPNQSESSD VVVQPYNSLL TLKRLTLHAD
210 220 230 240 250
AVVVLDNTAL DKIAVERLHL HKPDVQQINS LIATVMAAST TTLRYPGYMN
260 270 280 290 300
NDLVGLVASL IPTPRCHFLM TGYTPLTAEN AAGQVTSNIR KTTVLDVMRR
310 320 330 340 350
LLQPKNIMVS THTKSRDIAN AKYISILNII QGEVDPSQVH KSLQRIRERK
360 370 380 390 400
QANFIEWGPA SIQVALSKKS PYVQTAHRVS GLMLANHTSV RHLFNKVLRD
410 420 430 440 450
YEKLMGPKQE RQAFMQAYRD VPRFADAAGG GTALLEEFAD AKEVVQDLAN
460
EYAACESADY IQRQMMAS
Length:468
Mass (Da):52,158
Last modified:November 1, 1996 - v1
Checksum:iDA4BFBC3C03AD1C4
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti411R → A in AAB71841 (Ref. 2) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U31545 Genomic DNA. Translation: AAA82610.1.
AF013109 Genomic DNA. Translation: AAB71841.1.
PIRiT07904.
T08057.
RefSeqiXP_001691292.1. XM_001691240.1.
UniGeneiCre.1370.

Genome annotation databases

EnsemblPlantsiEDP05025; EDP05025; CHLREDRAFT_188933.
GeneIDi5716998.
GrameneiEDP05025; EDP05025; CHLREDRAFT_188933.
KEGGicre:CHLREDRAFT_188933.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U31545 Genomic DNA. Translation: AAA82610.1.
AF013109 Genomic DNA. Translation: AAB71841.1.
PIRiT07904.
T08057.
RefSeqiXP_001691292.1. XM_001691240.1.
UniGeneiCre.1370.

3D structure databases

ProteinModelPortaliQ39582.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3055.EDP05025.

Proteomic databases

PaxDbiQ39582.
PRIDEiQ39582.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiEDP05025; EDP05025; CHLREDRAFT_188933.
GeneIDi5716998.
GrameneiEDP05025; EDP05025; CHLREDRAFT_188933.
KEGGicre:CHLREDRAFT_188933.

Phylogenomic databases

eggNOGiKOG1374. Eukaryota.
COG5023. LUCA.
KOiK10389.
OMAiANEYAAC.

Family and domain databases

CDDicd02188. gamma_tubulin. 1 hit.
Gene3Di3.30.1330.20. 1 hit.
3.40.50.1440. 1 hit.
InterProiIPR002454. Gamma_tubulin.
IPR008280. Tub_FtsZ_C.
IPR000217. Tubulin.
IPR018316. Tubulin/FtsZ_2-layer-sand-dom.
IPR017975. Tubulin_CS.
IPR003008. Tubulin_FtsZ_GTPase.
[Graphical view]
PANTHERiPTHR11588. PTHR11588. 1 hit.
PTHR11588:SF7. PTHR11588:SF7. 1 hit.
PfamiPF00091. Tubulin. 1 hit.
PF03953. Tubulin_C. 1 hit.
[Graphical view]
PRINTSiPR01164. GAMMATUBULIN.
PR01161. TUBULIN.
SMARTiSM00864. Tubulin. 1 hit.
SM00865. Tubulin_C. 1 hit.
[Graphical view]
SUPFAMiSSF52490. SSF52490. 1 hit.
SSF55307. SSF55307. 1 hit.
PROSITEiPS00227. TUBULIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiTBG_CHLRE
AccessioniPrimary (citable) accession number: Q39582
Secondary accession number(s): O22417
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1996
Last modified: October 5, 2016
This is version 93 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.