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Q39566 (GSA_CHLRE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 29, 2013. Version 84. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Glutamate-1-semialdehyde 2,1-aminomutase, chloroplastic
Short name=GSA
EC=5.4.3.8
Alternative name(s):
Glutamate-1-semialdehyde aminotransferase
Short name=GSA-AT
Gene names
Name:GSA
OrganismChlamydomonas reinhardtii (Chlamydomonas smithii)
Taxonomic identifier3055 [NCBI]
Taxonomic lineageEukaryota › Viridiplantae › Chlorophyta › Chlorophyceae › Chlamydomonadales › Chlamydomonadaceae › Chlamydomonas

Protein attributes

Sequence length463 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

(S)-4-amino-5-oxopentanoate = 5-aminolevulinate.

Cofactor

Pyridoxal phosphate.

Pathway

Porphyrin-containing compound metabolism; protoporphyrin-IX biosynthesis; 5-aminolevulinate from L-glutamyl-tRNA(Glu): step 2/2.

Porphyrin-containing compound metabolism; chlorophyll biosynthesis.

Subunit structure

Homodimer By similarity.

Subcellular location

Plastid › chloroplast.

Sequence similarities

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. HemL subfamily.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 3030Chloroplast Potential
Chain31 – 463433Glutamate-1-semialdehyde 2,1-aminomutase, chloroplastic
PRO_0000001257

Amino acid modifications

Modified residue3031N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q39566 [UniParc].

Last modified November 1, 1997. Version 1.
Checksum: 9CB3BDF9A90C8010

FASTA46349,228
        10         20         30         40         50         60 
MQMQLNAKTV QGAFKAQRPR SVRGNVAVRA VAAPPKLVTK RSEEIFKEAQ ELLPGGVNSP 

        70         80         90        100        110        120 
VRAFRSVGGG PIVFDRVKGA YCWDVDGNKY IDYVGSWGPA ICGHGNDEVN NALKAQIDKG 

       130        140        150        160        170        180 
TSFGAPCELE NVLAKMVIDR VPSVEMVRFV SSGTEACLSV LRLMRAYTGR EKVLKFTGCY 

       190        200        210        220        230        240 
HGHADSFLVK AGSGVITLGL PDSPGVPKST AAATLTATYN NLDSVRELFA ANKGEIAGVI 

       250        260        270        280        290        300 
LEPVVGNSGF IVPTKEFLQG LREICTAEGA VLCFDEVMTG FRIAKGCAQE HFGITPDLTT 

       310        320        330        340        350        360 
MGKVIGGGMP VGAYGGKKEI MKMVAPAGPM YQAGTLSGNP MAMTAGIKTL EILGRPGAYE 

       370        380        390        400        410        420 
HLEKVTKRLI DGIMAAAKEH SHEITGGNIS GMFGFFFCKG PVTCFEDALA ADTAKFARFH 

       430        440        450        460 
RGMLEEGVYL APSQFEAGFT SLAHSEADVD ATIAAARRVF ARI

« Hide

References

[1]"Structure and light-regulated expression of the gsa gene encoding the chlorophyll biosynthetic enzyme, glutamate 1-semialdehyde aminotransferase, in Chlamydomonas reinhardtii."
Matters G.L., Beale S.I.
Plant Mol. Biol. 24:617-629(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: NO-.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		U03632 mRNA. Translation: AAA18861.1.
U03633 Unassigned DNA. Translation: AAA18862.1.
PIRS43787.
RefSeqXP_001697519.1. XM_001697467.1.
UniGeneCre.13379.

3D structure databases

ProteinModelPortalQ39566.
SMRQ39566. Positions 39-463.
ModBaseSearch...

Proteomic databases

PRIDEQ39566.
ProMEXQ39566.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID5723033.
KEGGcre:CHLREDRAFT_138524.

Phylogenomic databases

eggNOGCOG0001.
KOK01845.
OMAFNGNPIS.
ProtClustDBPLN02482.

Enzyme and pathway databases

UniPathwayUPA00251; UER00317.
UPA00668.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
InterProIPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERPTHR11986. PTHR11986. 1 hit.
PTHR11986:SF5. PTHR11986:SF5. 1 hit.
PfamPF00202. Aminotran_3. 1 hit.
[Graphical view]
SUPFAMSSF53383. PyrdxlP-dep_Trfase_major. 1 hit.
TIGRFAMsTIGR00713. hemL. 1 hit.
PROSITEPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameGSA_CHLRE
AccessionPrimary (citable) accession number: Q39566
Secondary accession number(s): Q39567
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: May 29, 2013
This is version 84 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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