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Q39566

- GSA_CHLRE

UniProt

Q39566 - GSA_CHLRE

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Protein

Glutamate-1-semialdehyde 2,1-aminomutase, chloroplastic

Gene

GSA

Organism
Chlamydomonas reinhardtii (Chlamydomonas smithii)
Status
Reviewed - Annotation score: 3 out of 5- Experimental evidence at protein leveli

Functioni

Catalytic activityi

(S)-4-amino-5-oxopentanoate = 5-aminolevulinate.

Cofactori

Pathwayi

GO - Molecular functioni

  1. glutamate-1-semialdehyde 2,1-aminomutase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro
  3. transaminase activity Source: InterPro

GO - Biological processi

  1. chlorophyll biosynthetic process Source: UniProtKB-UniPathway
  2. protoporphyrinogen IX biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Isomerase

Keywords - Biological processi

Chlorophyll biosynthesis, Porphyrin biosynthesis

Keywords - Ligandi

Pyridoxal phosphate

Enzyme and pathway databases

UniPathwayiUPA00251; UER00317.
UPA00668.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate-1-semialdehyde 2,1-aminomutase, chloroplastic (EC:5.4.3.8)
Short name:
GSA
Alternative name(s):
Glutamate-1-semialdehyde aminotransferase
Short name:
GSA-AT
Gene namesi
Name:GSA
OrganismiChlamydomonas reinhardtii (Chlamydomonas smithii)
Taxonomic identifieri3055 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeChlorophytaChlorophyceaeChlamydomonadalesChlamydomonadaceaeChlamydomonas

Subcellular locationi

GO - Cellular componenti

  1. chloroplast Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Chloroplast, Plastid

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transit peptidei1 – 3030ChloroplastSequence AnalysisAdd
BLAST
Chaini31 – 463433Glutamate-1-semialdehyde 2,1-aminomutase, chloroplasticPRO_0000001257Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei303 – 3031N6-(pyridoxal phosphate)lysineBy similarity

Proteomic databases

PRIDEiQ39566.
ProMEXiQ39566.

Interactioni

Subunit structurei

Homodimer.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ39566.
SMRiQ39566. Positions 39-463.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transit peptide

Phylogenomic databases

eggNOGiCOG0001.
KOiK01845.
OMAiRAIKPYP.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
HAMAPiMF_00375. HemL_aminotrans_3.
InterProiIPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00713. hemL. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q39566-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQMQLNAKTV QGAFKAQRPR SVRGNVAVRA VAAPPKLVTK RSEEIFKEAQ
60 70 80 90 100
ELLPGGVNSP VRAFRSVGGG PIVFDRVKGA YCWDVDGNKY IDYVGSWGPA
110 120 130 140 150
ICGHGNDEVN NALKAQIDKG TSFGAPCELE NVLAKMVIDR VPSVEMVRFV
160 170 180 190 200
SSGTEACLSV LRLMRAYTGR EKVLKFTGCY HGHADSFLVK AGSGVITLGL
210 220 230 240 250
PDSPGVPKST AAATLTATYN NLDSVRELFA ANKGEIAGVI LEPVVGNSGF
260 270 280 290 300
IVPTKEFLQG LREICTAEGA VLCFDEVMTG FRIAKGCAQE HFGITPDLTT
310 320 330 340 350
MGKVIGGGMP VGAYGGKKEI MKMVAPAGPM YQAGTLSGNP MAMTAGIKTL
360 370 380 390 400
EILGRPGAYE HLEKVTKRLI DGIMAAAKEH SHEITGGNIS GMFGFFFCKG
410 420 430 440 450
PVTCFEDALA ADTAKFARFH RGMLEEGVYL APSQFEAGFT SLAHSEADVD
460
ATIAAARRVF ARI
Length:463
Mass (Da):49,228
Last modified:November 1, 1997 - v1
Checksum:i9CB3BDF9A90C8010
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U03632 mRNA. Translation: AAA18861.1.
U03633 Unassigned DNA. Translation: AAA18862.1.
PIRiS43787.
RefSeqiXP_001697519.1. XM_001697467.1.
UniGeneiCre.13379.

Genome annotation databases

GeneIDi5723033.
KEGGicre:CHLREDRAFT_138524.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U03632 mRNA. Translation: AAA18861.1 .
U03633 Unassigned DNA. Translation: AAA18862.1 .
PIRi S43787.
RefSeqi XP_001697519.1. XM_001697467.1.
UniGenei Cre.13379.

3D structure databases

ProteinModelPortali Q39566.
SMRi Q39566. Positions 39-463.
ModBasei Search...
MobiDBi Search...

Proteomic databases

PRIDEi Q39566.
ProMEXi Q39566.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 5723033.
KEGGi cre:CHLREDRAFT_138524.

Phylogenomic databases

eggNOGi COG0001.
KOi K01845.
OMAi RAIKPYP.

Enzyme and pathway databases

UniPathwayi UPA00251 ; UER00317 .
UPA00668 .

Family and domain databases

Gene3Di 3.40.640.10. 1 hit.
3.90.1150.10. 2 hits.
HAMAPi MF_00375. HemL_aminotrans_3.
InterProi IPR004639. 4pyrrol_synth_GluAld_NH2Trfase.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view ]
PANTHERi PTHR11986. PTHR11986. 1 hit.
Pfami PF00202. Aminotran_3. 1 hit.
[Graphical view ]
PIRSFi PIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMi SSF53383. SSF53383. 1 hit.
TIGRFAMsi TIGR00713. hemL. 1 hit.
PROSITEi PS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Structure and light-regulated expression of the gsa gene encoding the chlorophyll biosynthetic enzyme, glutamate 1-semialdehyde aminotransferase, in Chlamydomonas reinhardtii."
    Matters G.L., Beale S.I.
    Plant Mol. Biol. 24:617-629(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: NO-.

Entry informationi

Entry nameiGSA_CHLRE
AccessioniPrimary (citable) accession number: Q39566
Secondary accession number(s): Q39567
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1997
Last modified: November 26, 2014
This is version 92 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3