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Protein
Submitted name:

Cyprosin

Gene
N/A
Organism
Cynara cardunculus (Cardoon)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei103PROSITE-ProRule annotation1
Active sitei290PROSITE-ProRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAspartyl proteasePROSITE-ProRule annotationSAAS annotation, Hydrolase, Protease

Protein family/group databases

MEROPSiA01.A02.

Names & Taxonomyi

Protein namesi
Submitted name:
CyprosinImported
OrganismiCynara cardunculus (Cardoon)Imported
Taxonomic identifieri4265 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridscampanulidsAsteralesAsteraceaeCarduoideaeCardueaeCarduinaeCynara

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 24Sequence analysisAdd BLAST24
ChainiPRO_500422221425 – 509Sequence analysisAdd BLAST485

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Glycosylationi400N-linked (GlcNAc...)PROSITE-ProRule annotation1

Structurei

3D structure databases

ProteinModelPortaliQ39476.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini85 – 506Peptidase A1InterPro annotationAdd BLAST422
Domaini315 – 355Saposin B-typeInterPro annotationAdd BLAST41
Domaini379 – 420Saposin B-typeInterPro annotationAdd BLAST42

Sequence similaritiesi

Belongs to the peptidase A1 family.PROSITE-ProRule annotationSAAS annotation

Keywords - Domaini

SignalSequence analysis

Family and domain databases

CDDicd06098. phytepsin. 1 hit.
Gene3Di1.10.225.10. 2 hits.
2.40.70.10. 3 hits.
InterProiView protein in InterPro
IPR001461. Aspartic_peptidase_A1.
IPR001969. Aspartic_peptidase_AS.
IPR033121. PEPTIDASE_A1.
IPR021109. Peptidase_aspartic_dom.
IPR033869. Phytepsin.
IPR007856. SapB_1.
IPR008138. SapB_2.
IPR011001. Saposin-like.
IPR008139. SaposinB_dom.
PANTHERiPTHR13683. PTHR13683. 1 hit.
PfamiView protein in Pfam
PF00026. Asp. 1 hit.
PF05184. SapB_1. 1 hit.
PF03489. SapB_2. 1 hit.
PRINTSiPR00792. PEPSIN.
SMARTiView protein in SMART
SM00741. SapB. 2 hits.
SUPFAMiSSF47862. SSF47862. 1 hit.
SSF50630. SSF50630. 2 hits.
PROSITEiView protein in PROSITE
PS00141. ASP_PROTEASE. 2 hits.
PS51767. PEPTIDASE_A1. 1 hit.
PS50015. SAP_B. 2 hits.

Sequencei

Sequence statusi: Complete.

Q39476-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGTAIKASVL ALFLFFLLSP TAFSVSNGGL LRVGLKKRKV DQINQLSGHG
60 70 80 90 100
VSMEAKARKD FGFGGALRDS GSDIIALKNY MDAQYYGEIG IGSPPQKFTV
110 120 130 140 150
IFDTGSSNLW VPSAKCYFSV ACLFHSKYKS SHSSTYKKNG TSAAIQYGTG
160 170 180 190 200
SISGFVSQDS VKLGDLVVKE QDFIEATKEP GITFLAAKFD GILGLGFQEI
210 220 230 240 250
SVGKSVPLWY NMVNQGLVQE PVFSFWFNRN ADEEEGGELV FGGVDPNHFK
260 270 280 290 300
GKHTYVPVTE KGYWQFDMGD VLIEDKTTGF CSDGCAAIAD SGTSLLAGPT
310 320 330 340 350
AIITEINHAI GAKGVMSQQC KTLVSQYGKT MIEMLLSEAQ PDKICSQMKL
360 370 380 390 400
CTFDGARDAS SIIESVVDEN NGKSSSGVHD EMCTFCEMAV VWMQNQIKRN
410 420 430 440 450
ETEDNIINYV NELCDRLPSP MGESAVDCNS LSSMPNIAFT IGGKVFELCP
460 470 480 490 500
EQYILKIGEG EAAQCISGFT AMDVAPPRGP LWILGDVFMG RYHTVFDYGK

LRVGFAEAA
Length:509
Mass (Da):55,177
Last modified:November 1, 1996 - v1
Checksum:i4E287C423F827A44
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X81984 mRNA. Translation: CAA57510.1.
PIRiS49349.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X81984 mRNA. Translation: CAA57510.1.
PIRiS49349.

3D structure databases

ProteinModelPortaliQ39476.
ModBaseiSearch...
MobiDBiSearch...

Protein family/group databases

MEROPSiA01.A02.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Family and domain databases

CDDicd06098. phytepsin. 1 hit.
Gene3Di1.10.225.10. 2 hits.
2.40.70.10. 3 hits.
InterProiView protein in InterPro
IPR001461. Aspartic_peptidase_A1.
IPR001969. Aspartic_peptidase_AS.
IPR033121. PEPTIDASE_A1.
IPR021109. Peptidase_aspartic_dom.
IPR033869. Phytepsin.
IPR007856. SapB_1.
IPR008138. SapB_2.
IPR011001. Saposin-like.
IPR008139. SaposinB_dom.
PANTHERiPTHR13683. PTHR13683. 1 hit.
PfamiView protein in Pfam
PF00026. Asp. 1 hit.
PF05184. SapB_1. 1 hit.
PF03489. SapB_2. 1 hit.
PRINTSiPR00792. PEPSIN.
SMARTiView protein in SMART
SM00741. SapB. 2 hits.
SUPFAMiSSF47862. SSF47862. 1 hit.
SSF50630. SSF50630. 2 hits.
PROSITEiView protein in PROSITE
PS00141. ASP_PROTEASE. 2 hits.
PS51767. PEPTIDASE_A1. 1 hit.
PS50015. SAP_B. 2 hits.
ProtoNetiSearch...

Entry informationi

Entry nameiQ39476_CYNCA
AccessioniPrimary (citable) accession number: Q39476
Entry historyiIntegrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: February 15, 2017
This is version 92 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Caution

Lacks conserved residue(s) required for the propagation of feature annotation.PROSITE-ProRule annotation

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.