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Protein

Zinc finger protein 4

Gene

ZFP4

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Acts as negative regulator of abscisic acid (ABA) signaling during germination and early seedling development.1 Publication

Miscellaneous

Seeds over-expressing ZFP4 are insensitive to inhibition of germination by abscisic acid (ABA).1 Publication

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri85 – 107C2H2-typePROSITE-ProRule annotationAdd BLAST23

GO - Molecular functioni

  • DNA binding transcription factor activity Source: TAIR
  • metal ion binding Source: UniProtKB-KW
  • sequence-specific DNA binding Source: TAIR
  • transcription regulatory region DNA binding Source: TAIR

GO - Biological processi

  • abscisic acid-activated signaling pathway Source: UniProtKB-KW
  • glucosinolate metabolic process Source: TAIR
  • negative regulation of abscisic acid-activated signaling pathway Source: UniProtKB
  • regulation of transcription, DNA-templated Source: TAIR

Keywordsi

Biological processAbscisic acid signaling pathway
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Recommended name:
Zinc finger protein 4Curated
Gene namesi
Name:ZFP41 Publication
Ordered Locus Names:At1g66140
ORF Names:F15E12.19
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G66140
TAIRilocus:2013820 AT1G66140

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Disruption phenotypei

No visible phenotype under normal growth conditions, but mutant seeds are hypersensitivite to inhibition of germination by abscisic acid (ABA).1 Publication

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000478451 – 260Zinc finger protein 4Add BLAST260

Proteomic databases

PaxDbiQ39263

PTM databases

iPTMnetiQ39263

Expressioni

Gene expression databases

ExpressionAtlasiQ39263 baseline and differential
GenevisibleiQ39263 AT

Interactioni

Protein-protein interaction databases

BioGridi28149, 2 interactors
STRINGi3702.AT1G66140.1

Structurei

3D structure databases

ProteinModelPortaliQ39263
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi12 – 18Poly-Ser7
Compositional biasi43 – 49Poly-Asn7
Compositional biasi72 – 77Poly-Gln6

Zinc finger

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Zinc fingeri85 – 107C2H2-typePROSITE-ProRule annotationAdd BLAST23

Keywords - Domaini

Zinc-finger

Phylogenomic databases

eggNOGiENOG410IZXQ Eukaryota
ENOG410ZCT7 LUCA
HOGENOMiHOG000239894
InParanoidiQ39263
OMAiNDNLGER
OrthoDBiEOG09360UI9
PhylomeDBiQ39263

Family and domain databases

InterProiView protein in InterPro
IPR036236 Znf_C2H2_sf
IPR013087 Znf_C2H2_type
SUPFAMiSSF57667 SSF57667, 1 hit
PROSITEiView protein in PROSITE
PS00028 ZINC_FINGER_C2H2_1, 1 hit
PS50157 ZINC_FINGER_C2H2_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q39263-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPILDLEIE ASSGSSSSQV ASNLSPVGED YKPISLNLSL SFNNNNNNNL
60 70 80 90 100
DLESSSLTLP LSSTSESSNP EQQQQQQPSV SKRVFSCNYC QRKFYSSQAL
110 120 130 140 150
GGHQNAHKRE RTLAKRAMRM GLAGVFPGRG SSSNYAAAAT AAALSCLPLH
160 170 180 190 200
GSGNGNMTSF RTLGIRAHSS AHDVSMTRQT PETLIRNIAR FNQGYFGNCI
210 220 230 240 250
PFYVEDDEAE MLWPGSFRQA TNAVAVEAGN DNLGERKMDF LDVKQAMDME
260
SSLPDLTLKL
Length:260
Mass (Da):28,309
Last modified:January 27, 2003 - v2
Checksum:i48484EC120250F09
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti119 – 143RMGLA…ATAAA → LWVLLGSSPVEDQVAIMRLL PQQP in AAA87300 (PubMed:7599312).CuratedAdd BLAST25

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L39647 mRNA Translation: AAA87300.1
AC026480 Genomic DNA Translation: AAG51296.1
CP002684 Genomic DNA Translation: AEE34466.1
AF361630 mRNA Translation: AAK32798.1
AY058087 mRNA Translation: AAL24195.1
AY056067 mRNA Translation: AAL06967.1
AK230229 mRNA Translation: BAF02034.1
AK230232 mRNA Translation: BAF02037.1
AK230250 mRNA Translation: BAF02053.1
PIRiB96686
S55884
RefSeqiNP_176788.1, NM_105285.3
UniGeneiAt.25527

Genome annotation databases

EnsemblPlantsiAT1G66140.1; AT1G66140.1; AT1G66140
GeneIDi842928
GrameneiAT1G66140.1; AT1G66140.1; AT1G66140
KEGGiath:AT1G66140

Similar proteinsi

Entry informationi

Entry nameiZFP4_ARATH
AccessioniPrimary (citable) accession number: Q39263
Secondary accession number(s): Q0WLF4, Q9C8D2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 27, 2003
Last sequence update: January 27, 2003
Last modified: April 25, 2018
This is version 127 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health