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Q39255

- SKP1A_ARATH

UniProt

Q39255 - SKP1A_ARATH

Protein

SKP1-like protein 1A

Gene

SKP1A

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed - Annotation score: 5 out of 5- Experimental evidence at protein leveli
  1. Functioni

    Involved in ubiquitination and subsequent proteasomal degradation of target proteins. Together with CUL1, RBX1 and a F-box protein, it forms a SCF E3 ubiquitin ligase complex. The functional specificity of this complex depends of the type of F-box protein. In the SCF complex, it serves as an adapter that links the F-box protein to CUL1. SCF(UFO) is required for vegetative and floral organ development as well as for male gametogenesis. SCF(TIR1) is involved in auxin signaling pathway. SCF(COI1) regulates responses to jasmonates. SCF(EID1) and SCF(AFR) are implicated in phytochrome A light signaling. SCF(ADO1), SCF(ADO2), SCF(ADO3) are related to the circadian clock. SCF(ORE9) seems to be involved in senescence. SCF(EBF1/EBF2) may regulate ethylene signaling. Plays a role during embryogenesis and early postembryonic development, especially during cell elongation and division. Contributes to the correct chromosome segregation during tetrad formation.6 Publications

    Pathwayi

    GO - Molecular functioni

    1. protein binding Source: UniProtKB

    GO - Biological processi

    1. auxin-activated signaling pathway Source: UniProtKB-KW
    2. chromosome segregation Source: UniProtKB-KW
    3. ethylene-activated signaling pathway Source: UniProtKB-KW
    4. microtubule cytoskeleton organization Source: TAIR
    5. multicellular organismal development Source: UniProtKB-KW
    6. negative regulation of DNA recombination Source: TAIR
    7. protein ubiquitination Source: UniProtKB-UniPathway
    8. response to cadmium ion Source: TAIR
    9. ubiquitin-dependent protein catabolic process Source: InterPro
    10. viral process Source: UniProtKB-KW

    Keywords - Molecular functioni

    Developmental protein

    Keywords - Biological processi

    Auxin signaling pathway, Chromosome partition, Ethylene signaling pathway, Host-virus interaction, Ubl conjugation pathway

    Enzyme and pathway databases

    UniPathwayiUPA00143.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    SKP1-like protein 1A
    Short name:
    SKP1-like 1
    Alternative name(s):
    UFO-binding protein 1
    Gene namesi
    Name:SKP1A
    Synonyms:ASK1, SKP1, UIP1
    Ordered Locus Names:At1g75950
    ORF Names:T4O12.17
    OrganismiArabidopsis thaliana (Mouse-ear cress)
    Taxonomic identifieri3702 [NCBI]
    Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
    ProteomesiUP000006548: Chromosome 1

    Organism-specific databases

    TAIRiAT1G75950.

    Subcellular locationi

    Nucleus 1 Publication. Cytoplasmcytoskeletonspindle 1 Publication. Cytoplasmcytoskeletonphragmoplast 1 Publication
    Note: Associated to mitotic spindle and phragmoplasts during cell division.

    GO - Cellular componenti

    1. cytosol Source: TAIR
    2. nucleus Source: TAIR
    3. phragmoplast Source: TAIR
    4. plasma membrane Source: TAIR
    5. spindle Source: TAIR

    Keywords - Cellular componenti

    Cytoplasm, Cytoskeleton, Nucleus

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 160160SKP1-like protein 1APRO_0000187255Add
    BLAST

    Proteomic databases

    PaxDbiQ39255.
    PRIDEiQ39255.

    Expressioni

    Tissue specificityi

    Accumulates only in meristematic cells. Expressed in inflorescence, shoot and root apical meristems, as well as in developing organs such as gametocytes and seeds. Also detected in cortical layer and epidermis of roots, leaves, pith and vascular bundle of young stem, young floral buds and organ primordia, pollen and through the valve of siliques. Not detectable in mature root tissues.5 Publications

    Developmental stagei

    During flower development, expressed in the tapetal layer surrounding the male microsporocytes, and in the endothelium layer surrounding the embryo sac within the ovule. During embryogenesis, expressed in all cells of the embryo and in developing endosperm surrounding the embryo, at the time of free nuclei proliferation.1 Publication

    Gene expression databases

    GenevestigatoriQ39255.

    Interactioni

    Subunit structurei

    Part of a SCF E3 ubiquitin ligase complex composed of SKP1, CUL1, RBX1 (RBX1A or RBX1B) and F-box proteins. Interacts with SKIP1, SKIP2, SKIP3, SKIP4, SKIP6, FIB1/SKIP7, SKIP8, PP2A11/SKIP10, SKIP11, PP2B11/SKIP12, PP2A14/SKIP13, SKIP14, SKIP15, SKIP16, SKIP19/FBL20, SKIP20, PP2B1/SKIP21, SKIP22, SKIP23, SKIP24, SKIP25, TULP10/SKIP26, SKIP27, SKIP28/MEE11, AFR/SKIP29, SKIP30, SKIP31, SKIP32/FBP7, SKIP33, SKIP35, ADO1/ZTL, ADO2/LKP2, ADO3/FKF1, AFR, COI1, DOR, EBF1, EBF2, EID1, ORE9, PP2A13/SKIP9, TIR1, UFO, SKP2A, CPR30, FBL17, At1g55000, At1g67340, At1g78100, At3g04660, At3g61590, At4g38940 and At5g49610. The SKP1A subunit of the SCF E3 ubiquitin ligase complex can interact directly with KIN10, KIN11 and the proteasome subunit PAD1. This interaction can be disrupted by PRL1. In case of polerovirus infection, part of a SCF P0 complex composed of the viral silencing suppressor P0, SKP1 and CUL1. Interacts with turnip yellows virus P0. Interacts with VBF and Agrobacterium virF.26 Publications

    Binary interactionsi

    WithEntry#Exp.IntActNotes
    Q659673EBI-532357,EBI-848577From a different organism.
    ADO1Q94BT69EBI-532357,EBI-300691
    AFRQ8LAW24EBI-532357,EBI-604438
    COI1O041977EBI-532357,EBI-401159
    CUL1Q94AH67EBI-532357,EBI-532411
    EBF1Q9SKK04EBI-532357,EBI-401198
    EID1Q8LEA84EBI-532357,EBI-687388
    GRH1Q9ZR123EBI-532357,EBI-617479
    IAA7Q388252EBI-532357,EBI-602959
    PP2A13Q9LEX04EBI-532357,EBI-604261
    SKIP1Q9FDX15EBI-532357,EBI-604228
    SKIP15O492794EBI-532357,EBI-591174
    SKIP2Q9FE833EBI-532357,EBI-591107
    SKIP28Q9ZU903EBI-532357,EBI-604427
    TIR1Q570C04EBI-532357,EBI-307183
    UFOQ390906EBI-532357,EBI-590758
    virFP155976EBI-532357,EBI-605118From a different organism.

    Protein-protein interaction databases

    BioGridi29147. 125 interactions.
    DIPiDIP-31325N.
    IntActiQ39255. 67 interactions.

    Structurei

    Secondary structure

    1
    160
    Legend: HelixTurnBeta strand
    Show more details
    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Beta strandi6 – 94
    Beta strandi11 – 133
    Beta strandi15 – 184
    Helixi21 – 244
    Turni27 – 293
    Turni31 – 366
    Helixi37 – 404
    Helixi49 – 579
    Beta strandi89 – 913
    Helixi102 – 1076
    Helixi111 – 12313
    Turni124 – 1274
    Helixi130 – 1367
    Helixi145 – 15915

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    2P1MX-ray1.80A1-160[»]
    2P1NX-ray2.50A/D1-160[»]
    2P1OX-ray1.90A1-160[»]
    2P1PX-ray2.21A1-160[»]
    2P1QX-ray1.91A1-160[»]
    3C6NX-ray2.60A1-160[»]
    3C6OX-ray2.70A1-160[»]
    3C6PX-ray2.70A1-160[»]
    3OGKX-ray2.80A/C/E/G/I/K/M/O1-160[»]
    3OGLX-ray3.18A/C/E/G/I/K/M/O1-160[»]
    3OGMX-ray3.34A/C/E/G/I/K/M/O1-160[»]
    ProteinModelPortaliQ39255.
    SMRiQ39255. Positions 5-160.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ39255.

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni102 – 16059Interaction with the F-box domain of F-box proteinsAdd
    BLAST

    Sequence similaritiesi

    Belongs to the SKP1 family.Curated

    Phylogenomic databases

    eggNOGiCOG5201.
    HOGENOMiHOG000172184.
    InParanoidiQ39255.
    KOiK03094.
    OMAiVIEWATH.
    PhylomeDBiQ39255.

    Family and domain databases

    Gene3Di3.30.710.10. 1 hit.
    InterProiIPR011333. BTB/POZ_fold.
    IPR016897. E3_ubiquit_lig_SCF_Skp.
    IPR001232. Skp1_comp.
    IPR016072. Skp1_comp_dimer.
    IPR016073. Skp1_comp_POZ.
    [Graphical view]
    PANTHERiPTHR11165. PTHR11165. 1 hit.
    PfamiPF01466. Skp1. 1 hit.
    PF03931. Skp1_POZ. 1 hit.
    [Graphical view]
    PIRSFiPIRSF028729. E3_ubiquit_lig_SCF_Skp. 1 hit.
    SMARTiSM00512. Skp1. 1 hit.
    [Graphical view]
    SUPFAMiSSF54695. SSF54695. 1 hit.
    SSF81382. SSF81382. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q39255-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSAKKIVLKS SDGESFEVEE AVALESQTIA HMVEDDCVDN GVPLPNVTSK    50
    ILAKVIEYCK RHVEAAASKA EAVEGAATSD DDLKAWDADF MKIDQATLFE 100
    LILAANYLNI KNLLDLTCQT VADMIKGKTP EEIRTTFNIK NDFTPEEEEE 150
    VRRENQWAFE 160
    Length:160
    Mass (Da):17,857
    Last modified:November 1, 1996 - v1
    Checksum:i56B84C19FD5ABF17
    GO

    Sequence cautioni

    The sequence AAB38862.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.

    Experimental Info

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Sequence conflicti43 – 431P → L in AAB38862. (PubMed:9530878)Curated

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U60981 mRNA. Translation: AAB17535.1.
    U97020 mRNA. Translation: AAC63109.1.
    AF059294 mRNA. Translation: AAC14444.1.
    AC007396 Genomic DNA. Translation: AAF26761.1.
    CP002684 Genomic DNA. Translation: AEE35780.1.
    AY080884 mRNA. Translation: AAL87354.1.
    AY113971 mRNA. Translation: AAM45019.1.
    U70034 mRNA. Translation: AAB38862.1. Different initiation.
    PIRiT51309.
    RefSeqiNP_565123.1. NM_106245.4.
    UniGeneiAt.23531.

    Genome annotation databases

    EnsemblPlantsiAT1G75950.1; AT1G75950.1; AT1G75950.
    GeneIDi843928.
    KEGGiath:AT1G75950.

    Cross-referencesi

    Web resourcesi

    PlantsUBQ

    A functional genomics database for the ubiquitin/26S proteasome proteolytic pathway in plants

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U60981 mRNA. Translation: AAB17535.1 .
    U97020 mRNA. Translation: AAC63109.1 .
    AF059294 mRNA. Translation: AAC14444.1 .
    AC007396 Genomic DNA. Translation: AAF26761.1 .
    CP002684 Genomic DNA. Translation: AEE35780.1 .
    AY080884 mRNA. Translation: AAL87354.1 .
    AY113971 mRNA. Translation: AAM45019.1 .
    U70034 mRNA. Translation: AAB38862.1 . Different initiation.
    PIRi T51309.
    RefSeqi NP_565123.1. NM_106245.4.
    UniGenei At.23531.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    2P1M X-ray 1.80 A 1-160 [» ]
    2P1N X-ray 2.50 A/D 1-160 [» ]
    2P1O X-ray 1.90 A 1-160 [» ]
    2P1P X-ray 2.21 A 1-160 [» ]
    2P1Q X-ray 1.91 A 1-160 [» ]
    3C6N X-ray 2.60 A 1-160 [» ]
    3C6O X-ray 2.70 A 1-160 [» ]
    3C6P X-ray 2.70 A 1-160 [» ]
    3OGK X-ray 2.80 A/C/E/G/I/K/M/O 1-160 [» ]
    3OGL X-ray 3.18 A/C/E/G/I/K/M/O 1-160 [» ]
    3OGM X-ray 3.34 A/C/E/G/I/K/M/O 1-160 [» ]
    ProteinModelPortali Q39255.
    SMRi Q39255. Positions 5-160.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    BioGridi 29147. 125 interactions.
    DIPi DIP-31325N.
    IntActi Q39255. 67 interactions.

    Proteomic databases

    PaxDbi Q39255.
    PRIDEi Q39255.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblPlantsi AT1G75950.1 ; AT1G75950.1 ; AT1G75950 .
    GeneIDi 843928.
    KEGGi ath:AT1G75950.

    Organism-specific databases

    GeneFarmi 4981.
    TAIRi AT1G75950.

    Phylogenomic databases

    eggNOGi COG5201.
    HOGENOMi HOG000172184.
    InParanoidi Q39255.
    KOi K03094.
    OMAi VIEWATH.
    PhylomeDBi Q39255.

    Enzyme and pathway databases

    UniPathwayi UPA00143 .

    Miscellaneous databases

    EvolutionaryTracei Q39255.
    PROi Q39255.

    Gene expression databases

    Genevestigatori Q39255.

    Family and domain databases

    Gene3Di 3.30.710.10. 1 hit.
    InterProi IPR011333. BTB/POZ_fold.
    IPR016897. E3_ubiquit_lig_SCF_Skp.
    IPR001232. Skp1_comp.
    IPR016072. Skp1_comp_dimer.
    IPR016073. Skp1_comp_POZ.
    [Graphical view ]
    PANTHERi PTHR11165. PTHR11165. 1 hit.
    Pfami PF01466. Skp1. 1 hit.
    PF03931. Skp1_POZ. 1 hit.
    [Graphical view ]
    PIRSFi PIRSF028729. E3_ubiquit_lig_SCF_Skp. 1 hit.
    SMARTi SM00512. Skp1. 1 hit.
    [Graphical view ]
    SUPFAMi SSF54695. SSF54695. 1 hit.
    SSF81382. SSF81382. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "Budding yeast SKP1 encodes an evolutionarily conserved kinetochore protein required for cell cycle progression."
      Connelly C., Hieter P.
      Cell 86:275-285(1996) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    2. "The UNUSUAL FLORAL ORGANS gene of Arabidopsis thaliana is an F-box protein required for normal patterning and growth in the floral meristem."
      Samach A., Klenz J.E., Kohalmi S.E., Risseeuw E., Haughn G.W., Crosby W.L.
      Plant J. 20:433-445(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, INTERACTION WITH UFO.
      Strain: cv. Columbia.
    3. "Overexpression of Arabidopsis thaliana SKP1 homologues in yeast inactivates the Mig1 repressor by destabilising the F-box protein Grr1."
      Schouten J., de Kam R.J., Fetter K., Hoge J.H.C.
      Mol. Gen. Genet. 263:309-319(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA].
      Strain: cv. Landsberg erecta.
    4. "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana."
      Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O., Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E., Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K.
      , Conn L., Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P., Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D., Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J., Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L., Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A., Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A., Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M., Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M., Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P., Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D., Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D., Yu G., Fraser C.M., Venter J.C., Davis R.W.
      Nature 408:816-820(2000) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: cv. Columbia.
    5. The Arabidopsis Information Resource (TAIR)
      Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
      Cited for: GENOME REANNOTATION.
      Strain: cv. Columbia.
    6. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
      Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
      , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
      Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
      Strain: cv. Columbia.
    7. "Arabidopsis SKP1, a homologue of a cell cycle regulator gene, is predominantly expressed in meristematic cells."
      Porat R., Lu P., O'Neill S.D.
      Planta 204:345-351(1998) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 13-160, DEVELOPMENTAL STAGE, TISSUE SPECIFICITY.
      Strain: cv. Columbia.
    8. "The ASK1 gene regulates development and interacts with the UFO gene to control floral organ identity in Arabidopsis."
      Zhao D., Yang M., Solava J., Ma H.
      Dev. Genet. 25:209-223(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    9. "Identification of an SCF ubiquitin-ligase complex required for auxin response in Arabidopsis thaliana."
      Gray W.M., del Pozo J.C., Walker L., Hobbie L., Risseeuw E., Banks T., Crosby W.L., Yang M., Ma H., Estelle M.
      Genes Dev. 13:1678-1691(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, INTERACTION WITH TIR1.
    10. "The Arabidopsis SKP1-LIKE1 gene is essential for male meiosis and may control homologue separation."
      Yang M., Hu Y., Lodhi M., McCombie W.R., Ma H.
      Proc. Natl. Acad. Sci. U.S.A. 96:11416-11421(1999) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    11. "The ASK1 gene regulates B function gene expression in cooperation with UFO and LEAFY in Arabidopsis."
      Zhao D., Yu Q., Chen M., Ma H.
      Development 128:2735-2746(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION.
    12. "SKP1-SnRK protein kinase interactions mediate proteasomal binding of a plant SCF ubiquitin ligase."
      Farras R., Ferrando A., Jasik J., Kleinow T., Oekresz L., Tiburcio A., Salchert K., del Pozo C., Schell J., Koncz C.
      EMBO J. 20:2742-2756(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: SUBCELLULAR LOCATION, INTERACTION WITH SKIP1; SKIP2; SKIP3; SKIP4; SKIP6; FIB1; CUL1; PAD1; KIN10 AND KIN11.
    13. "EID1, an F-box protein involved in phytochrome A-specific light signaling."
      Dieterle M., Zhou Y.-C., Schaefer E., Funk M., Kretsch T.
      Genes Dev. 15:939-944(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH EID1.
    14. "ORE9, an F-box protein that regulates leaf senescence in Arabidopsis."
      Woo H.R., Chung K.M., Park J.-H., Oh S.A., Ahn T., Hong S.H., Jang S.K., Nam H.G.
      Plant Cell 13:1779-1790(2001) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH ORE9.
    15. "The AtRbx1 protein is part of plant SCF complexes, and its down-regulation causes severe growth and developmental defects."
      Lechner E., Xie D., Grava S., Pigaglio E., Planchais S., Murray J.A.H., Parmentier Y., Mutterer J., Dubreucq B., Shen W.-H., Genschik P.
      J. Biol. Chem. 277:50069-50080(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: IDENTIFICATION IN A SCF COMPLEX.
    16. "The SCF(COI1) ubiquitin-ligase complexes are required for jasmonate response in Arabidopsis."
      Xu L., Liu F., Lechner E., Genschik P., Crosby W.L., Ma H., Peng W., Huang D., Xie D.
      Plant Cell 14:1919-1935(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH COI1, IDENTIFICATION IN A SCF(COI1) COMPLEX.
    17. "COI1 links jasmonate signalling and fertility to the SCF ubiquitin-ligase complex in Arabidopsis."
      Devoto A., Nieto-Rostro M., Xie D., Ellis C., Harmston R., Patrick E., Davis J., Sherratt L., Coleman M., Turner J.G.
      Plant J. 32:457-466(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH COI1, IDENTIFICATION IN A SCF(COI1) COMPLEX.
    18. "The F-box subunit of the SCF E3 complex is encoded by a diverse superfamily of genes in Arabidopsis."
      Gagne J.M., Downes B.P., Shiu S.-H., Durski A.M., Vierstra R.D.
      Proc. Natl. Acad. Sci. U.S.A. 99:11519-11524(2002) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH UFO; PP2A13; AT1G67340; AT4G38940; SKIP15; AT3G04660; AT1G78100; AT1G55000; SKIP16; SKIP2; SKIP32 AND EBF1.
    19. "Plant responses to ethylene gas are mediated by SCF(EBF1/EBF2)-dependent proteolysis of EIN3 transcription factor."
      Guo H., Ecker J.R.
      Cell 115:667-677(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH EBF1 AND EBF2.
    20. "The F box protein AFR is a positive regulator of phytochrome A-mediated light signaling."
      Harmon F.G., Kay S.A.
      Curr. Biol. 13:2091-2096(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH AFR.
    21. "Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis."
      Risseeuw E.P., Daskalchuk T.E., Banks T.W., Liu E., Cotelesage J., Hellmann H., Estelle M., Somers D.E., Crosby W.L.
      Plant J. 34:753-767(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH EID1; SKIP1; SKIP6; SKIP8; PP2A13/SKIP9; PP2A11/SKIP10; SKIP11; PP2B11/SKIP12; PP2A14/SKIP13; SKIP14; SKIP19/FBL20; SKIP20; PP2B1/SKIP21; SKIP22; SKIP23; SKIP24; SKIP25; TULP10/SKIP26; SKIP27; SKIP28/MEE11; AFR/SKIP29; SKIP30; SKIP31; SKIP32/FBP7; SKIP33 AND SKIP35.
    22. "The F-box-containing protein UFO and AGAMOUS participate in antagonistic pathways governing early petal development in Arabidopsis."
      Durfee T., Roe J.L., Sessions R.A., Inouye C., Serikawa K., Feldmann K.A., Weigel D., Zambryski P.C.
      Proc. Natl. Acad. Sci. U.S.A. 100:8571-8576(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH UFO.
    23. "Members of the Arabidopsis-SKP1-like gene family exhibit a variety of expression patterns and may play diverse roles in Arabidopsis."
      Zhao D., Ni W., Feng B., Han T., Petrasek M.G., Ma H.
      Plant Physiol. 133:203-217(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, TISSUE SPECIFICITY.
    24. "Identification of ASK and clock-associated proteins as molecular partners of LKP2 (LOV kelch protein 2) in Arabidopsis."
      Yasuhara M., Mitsui S., Hirano H., Takanabe R., Tokioka Y., Ihara N., Komatsu A., Seki M., Shinozaki K., Kiyosue T.
      J. Exp. Bot. 55:2015-2027(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH ADO1; ADO2 AND ADO3.
    25. "Involvement of targeted proteolysis in plant genetic transformation by Agrobacterium."
      Tzfira T., Vaidya M., Citovsky V.
      Nature 431:87-92(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH AGROBACTERIUM VIRF.
    26. "The ASK1 and ASK2 genes are essential for Arabidopsis early development."
      Liu F., Ni W., Griffith M.E., Huang Z., Chang C., Peng W., Ma H., Xie D.
      Plant Cell 16:5-20(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: FUNCTION, TISSUE SPECIFICITY.
    27. "Expression and interaction analysis of Arabidopsis Skp1-related genes."
      Takahashi N., Kuroda H., Kuromori T., Hirayama T., Seki M., Shinozaki K., Shimada H., Matsui M.
      Plant Cell Physiol. 45:83-91(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: TISSUE SPECIFICITY, INTERACTION WITH EBF1/FBL6; COI1/FBL2; ADO3/FKF1; AT3G61590 AND AT5G49610.
    28. "Formation of an SCF(ZTL) complex is required for proper regulation of circadian timing."
      Han L., Mason M., Risseeuw E.P., Crosby W.L., Somers D.E.
      Plant J. 40:291-301(2004) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH ADO1.
    29. Cited for: INTERACTION WITH TURNIP YELLOWS VIRUS PROTEIN P0, IDENTIFICATION IN A SCF P0 COMPLEX.
    30. "Control of plant germline proliferation by SCF(FBL17) degradation of cell cycle inhibitors."
      Kim H.J., Oh S.A., Brownfield L., Hong S.H., Ryu H., Hwang I., Twell D., Nam H.G.
      Nature 455:1134-1137(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH FBL17.
    31. "SKP2A, an F-box protein that regulates cell division, is degraded via the ubiquitin pathway."
      Jurado S., Diaz-Trivino S., Abraham Z., Manzano C., Gutierrez C., del Pozo C.
      Plant J. 53:828-841(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH SKP2A.
    32. "F-box protein DOR functions as a novel inhibitory factor for abscisic acid-induced stomatal closure under drought stress in Arabidopsis."
      Zhang Y., Xu W., Li Z., Deng X.W., Wu W., Xue Y.
      Plant Physiol. 148:2121-2133(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH DOR.
    33. "An F-box gene, CPR30, functions as a negative regulator of the defense response in Arabidopsis."
      Gou M., Su N., Zheng J., Huai J., Wu G., Zhao J., He J., Tang D., Yang S., Wang G.
      Plant J. 60:757-770(2009) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH CPR30.
    34. "Agrobacterium induces expression of a host F-box protein required for tumorigenicity."
      Zaltsman A., Krichevsky A., Loyter A., Citovsky V.
      Cell Host Microbe 7:197-209(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: INTERACTION WITH VBF.
    35. Cited for: X-RAY CRYSTALLOGRAPHY (1.8 ANGSTROMS) IN COMPLEX WITH TIR1; AUXIN; AUX/IAA POLYPEPTIDE SUBSTRATE; AUXIN ANALOGS AND MYO-INOSITOL HEXAKISPHOSPHATE.
    36. "Small-molecule agonists and antagonists of F-box protein-substrate interactions in auxin perception and signaling."
      Hayashi K., Tan X., Zheng N., Hatate T., Kimura Y., Kepinski S., Nozaki H.
      Proc. Natl. Acad. Sci. U.S.A. 105:5632-5637(2008) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) IN COMPLEX WITH SKP1A; AUX/IAA POLYPEPTIDE SUBSTRATE; AUXIN; AUXIN AGONISTS; AUXIN ANTAGONISTS AND MYO-INOSITOL HEXAKISPHOSPHATE.
    37. Cited for: X-RAY CRYSTALLOGRAPHY (2.80 ANGSTROMS) OF 1-160, INTERACTION WITH COI1.

    Entry informationi

    Entry nameiSKP1A_ARATH
    AccessioniPrimary (citable) accession number: Q39255
    Secondary accession number(s): P92992
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 19, 2005
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 115 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programPlant Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    3D-structure, Complete proteome, Reference proteome

    Documents

    1. Arabidopsis thaliana
      Arabidopsis thaliana: entries and gene names
    2. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    3. PDB cross-references
      Index of Protein Data Bank (PDB) cross-references
    4. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3