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Protein

Transcription factor TGA3

Gene

TGA3

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Transcriptional activator that binds specifically to the DNA sequence 5'-TGACG-3'. Recognizes ocs elements like the as-1 motif of the cauliflower mosaic virus 35S promoter. Binding to the as-1-like cis elements mediate auxin- and salicylic acid-inducible transcription. Required to induce the systemic acquired resistance (SAR) via the regulation of pathogenesis-related genes expression. Binding to the as-1 element of PR-1 promoter is salicylic acid-inducible and mediated by NPR1. Could also bind to the Hex-motif (5'-TGACGTGG-3') another cis-acting element found in plant histone promoters.1 Publication

GO - Molecular functioni

  • calmodulin binding Source: TAIR
  • DNA binding transcription factor activity Source: TAIR
  • sequence-specific DNA binding Source: TAIR

GO - Biological processi

  • defense response to bacterium Source: TAIR
  • plant-type hypersensitive response Source: UniProtKB-KW
  • systemic acquired resistance, salicylic acid mediated signaling pathway Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionActivator, DNA-binding
Biological processHypersensitive response, Plant defense, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription factor TGA3
Alternative name(s):
bZIP transcription factor 22
Short name:
AtbZIP22
Gene namesi
Name:TGA3
Synonyms:BZIP22
Ordered Locus Names:At1g22070
ORF Names:F2E2.14
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G22070
TAIRilocus:2030551 AT1G22070

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00000765551 – 384Transcription factor TGA3Add BLAST384

Proteomic databases

PaxDbiQ39234

Expressioni

Tissue specificityi

Expressed in the whole plant.2 Publications

Gene expression databases

ExpressionAtlasiQ39234 baseline and differential
GenevisibleiQ39234 AT

Interactioni

Subunit structurei

Binds DNA as a dimer. Interacts with NPR1, NPR3 and NPR4. Interacts with GRXC7/ROXY1.4 Publications

Binary interactionsi

Show more details

GO - Molecular functioni

  • calmodulin binding Source: TAIR

Protein-protein interaction databases

BioGridi24051, 6 interactors
IntActiQ39234, 18 interactors
STRINGi3702.AT1G22070.1

Structurei

3D structure databases

ProteinModelPortaliQ39234
SMRiQ39234
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini96 – 159bZIPPROSITE-ProRule annotationAdd BLAST64
Domaini167 – 379DOG1PROSITE-ProRule annotationAdd BLAST213

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni98 – 118Basic motifPROSITE-ProRule annotationAdd BLAST21
Regioni124 – 138Leucine-zipperPROSITE-ProRule annotationAdd BLAST15

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili98 – 151Sequence analysisAdd BLAST54
Coiled coili267 – 296Sequence analysisAdd BLAST30

Sequence similaritiesi

Belongs to the bZIP family.Curated

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiENOG410IKSN Eukaryota
ENOG410YEGW LUCA
HOGENOMiHOG000116597
InParanoidiQ39234
KOiK14431
OMAiDICLNHY
OrthoDBiEOG09360E5Y
PhylomeDBiQ39234

Family and domain databases

InterProiView protein in InterPro
IPR004827 bZIP
IPR025422 TGA_domain
PfamiView protein in Pfam
PF07716 bZIP_2, 1 hit
PF14144 DOG1, 1 hit
SMARTiView protein in SMART
SM00338 BRLZ, 1 hit
PROSITEiView protein in PROSITE
PS50217 BZIP, 1 hit
PS00036 BZIP_BASIC, 1 hit
PS51806 DOG1, 1 hit

Sequencei

Sequence statusi: Complete.

Q39234-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEMMSSSSST TQVVSFRDMG MYEPFQQLSG WESPFKSDIN NITSNQNNNQ
60 70 80 90 100
SSSTTLEVDA RPEADDNNRV NYTSVYNNSL EAEPSSNNDQ DEDRINDKMK
110 120 130 140 150
RRLAQNREAA RKSRLRKKAH VQQLEESRLK LSQLEQELVR ARQQGLCVRN
160 170 180 190 200
SSDTSYLGPA GNMNSGIAAF EMEYTHWLEE QNRRVSEIRT ALQAHIGDIE
210 220 230 240 250
LKMLVDSCLN HYANLFRMKA DAAKADVFFL MSGMWRTSTE RFFQWIGGFR
260 270 280 290 300
PSELLNVVMP YVEPLTDQQL LEVRNLQQSS QQAEEALSQG LDKLQQGLVE
310 320 330 340 350
SIAIQIKVVE SVNHGAPMAS AMENLQALES FVNQADHLRQ QTLQQMSKIL
360 370 380
TTRQAARGLL ALGEYFHRLR ALSSLWAARP REHT
Length:384
Mass (Da):43,755
Last modified:November 1, 1996 - v1
Checksum:i48F965F62A2980A9
GO

Sequence cautioni

The sequence AAF86550 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAM64781 differs from that shown. Reason: Erroneous initiation.Curated

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti58V → F in AAM64781 (Ref. 4) Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L10209 mRNA Translation: AAA32873.1
AC069252 Genomic DNA Translation: AAF86550.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE30193.1
AY087225 mRNA Translation: AAM64781.1 Different initiation.
PIRiF86353
S46523
RefSeqiNP_564156.1, NM_102057.4
UniGeneiAt.15614

Genome annotation databases

EnsemblPlantsiAT1G22070.1; AT1G22070.1; AT1G22070
GeneIDi838812
GrameneiAT1G22070.1; AT1G22070.1; AT1G22070
KEGGiath:AT1G22070

Similar proteinsi

Entry informationi

Entry nameiTGA3_ARATH
AccessioniPrimary (citable) accession number: Q39234
Secondary accession number(s): Q8LBG4, Q9LM52
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 1, 2004
Last sequence update: November 1, 1996
Last modified: April 25, 2018
This is version 141 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health