Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

SEC12-like protein 2

Gene

STL2P

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Required for the formation or budding of transport vesicles from the ER.1 Publication

Miscellaneous

In the process of transport, may migrate to the Golgi apparatus and function in subsequent transport events.By similarity

GO - Molecular functioni

GO - Biological processi

  • ER to Golgi vesicle-mediated transport Source: TAIR
  • protein secretion Source: GO_Central
  • regulation of COPII vesicle coating Source: GO_Central

Keywordsi

Biological processER-Golgi transport, Protein transport, Transport

Enzyme and pathway databases

ReactomeiR-ATH-204005 COPII (Coat Protein 2) Mediated Vesicle Transport

Names & Taxonomyi

Protein namesi
Recommended name:
SEC12-like protein 2
Gene namesi
Name:STL2P
Synonyms:ST12P
Ordered Locus Names:At2g01470
ORF Names:F2I9.9
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G01470
TAIRilocus:2049582 AT2G01470

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Topological domaini2 – 367CytoplasmicSequence analysisAdd BLAST366
Transmembranei368 – 388Helical; Signal-anchor for type II membrane proteinSequence analysisAdd BLAST21
Topological domaini389 – 393LumenalSequence analysis5

Keywords - Cellular componenti

Endoplasmic reticulum, Golgi apparatus, Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Initiator methionineiRemovedCombined sources
ChainiPRO_00000512292 – 393SEC12-like protein 2Add BLAST392

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei2N-acetylalanineCombined sources1
Modified residuei43PhosphoserineCombined sources1

Keywords - PTMi

Acetylation, Phosphoprotein

Proteomic databases

PaxDbiQ39221

PTM databases

iPTMnetiQ39221

Expressioni

Gene expression databases

ExpressionAtlasiQ39221 baseline and differential
GenevisibleiQ39221 AT

Interactioni

Subunit structurei

Interacts with BZIP28.1 Publication

GO - Molecular functioni

Protein-protein interaction databases

BioGridi78, 1 interactor
STRINGi3702.AT2G01470.1

Structurei

3D structure databases

ProteinModelPortaliQ39221
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Repeati151 – 190WD 1Add BLAST40
Repeati193 – 231WD 2Add BLAST39
Repeati283 – 322WD 3Add BLAST40
Repeati326 – 367WD 4Add BLAST42

Compositional bias

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Compositional biasi49 – 58Poly-Ser10

Keywords - Domaini

Repeat, Signal-anchor, Transmembrane, Transmembrane helix, WD repeat

Phylogenomic databases

eggNOGiKOG0771 Eukaryota
ENOG410XRQK LUCA
HOGENOMiHOG000070543
InParanoidiQ39221
KOiK14003
OMAiAHSMFVT
OrthoDBiEOG09360GBW
PhylomeDBiQ39221

Family and domain databases

Gene3Di2.130.10.10, 1 hit
InterProiView protein in InterPro
IPR011047 Quinoprotein_ADH-like_supfam
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR017986 WD40_repeat_dom
PfamiView protein in Pfam
PF00400 WD40, 2 hits
SMARTiView protein in SMART
SM00320 WD40, 4 hits
SUPFAMiSSF50998 SSF50998, 1 hit
PROSITEiView protein in PROSITE
PS50294 WD_REPEATS_REGION, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q39221-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MANQSTETNQ PSNMQTYGVP IYAADWIPEV DVRSKIIMDP EKSEDDDESS
60 70 80 90 100
SSSSSSRSCI VLSGGGGEGR SGISNVILIC RVDLNTNSLS EQPLGRLVVG
110 120 130 140 150
SDLPYRMAVH PREGGLICAL PNSCKLFHWE DIMSREDNQA GESEEVIKEL
160 170 180 190 200
RDVGQQLALA FNPEGSVLAA GAEDGTLRVF KWPSMNTLLN ESQAHSSVKC
210 220 230 240 250
LTFSESGQFL VSLGGPVCRV WDVNASAAVA SLSKEKDEMF ASCRFSVDSA
260 270 280 290 300
GNEVLYIAAN TERGGSIITC DTKLWKRKWS KPIKKNSISA FNVSADGKLL
310 320 330 340 350
AIGTLEGDVL ILESTRMQTI QVVKKAHLGL VTALTFSPDS RGLVSVSFDS
360 370 380 390
RARLTMIEQK GDKPGVRWWL LVLLIVLLYV VAYYYMKAKG IIP
Length:393
Mass (Da):42,794
Last modified:January 10, 2006 - v4
Checksum:iD076454309A15013
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti322V → I in AAA32871 (PubMed:1396601).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M95796 mRNA Translation: AAA32871.1
AC005560 Genomic DNA Translation: AAC67323.1
CP002685 Genomic DNA Translation: AEC05458.1
AY065198 mRNA Translation: AAL38374.1
AY074332 mRNA Translation: AAL67028.1
AY123030 mRNA Translation: AAM67563.1
PIRiB84425
S28604
T48907
RefSeqiNP_178256.1, NM_126208.4
UniGeneiAt.323

Genome annotation databases

EnsemblPlantsiAT2G01470.1; AT2G01470.1; AT2G01470
GeneIDi814675
GrameneiAT2G01470.1; AT2G01470.1; AT2G01470
KEGGiath:AT2G01470

Similar proteinsi

Entry informationi

Entry nameiSTLP2_ARATH
AccessioniPrimary (citable) accession number: Q39221
Secondary accession number(s): Q7EP29, Q8VZ72
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: January 10, 2006
Last modified: April 25, 2018
This is version 131 of the entry and version 4 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health