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Protein

Defensin-like protein 2

Gene

PDF2.2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

Confers broad-spectrum resistance to pathogens.

GO - Biological processi

  • defense response Source: TAIR
  • defense response to fungus Source: UniProtKB-KW
  • killing of cells of other organism Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Antimicrobial, Fungicide

Keywords - Biological processi

Plant defense

Names & Taxonomyi

Protein namesi
Recommended name:
Defensin-like protein 2
Alternative name(s):
Low-molecular-weight cysteine-rich protein 69
Short name:
Protein LCR69
Plant defensin 2.2
Gene namesi
Name:PDF2.2
Synonyms:LCR69
Ordered Locus Names:At2g02100
ORF Names:F5O4.13
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G02100.

Subcellular locationi

GO - Cellular componenti

  • cell wall Source: TAIR
  • extracellular region Source: UniProtKB-SubCell
  • plant-type cell wall Source: TAIR
  • plasma membrane Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 30Sequence analysisAdd BLAST30
ChainiPRO_000000702431 – 77Defensin-like protein 2Add BLAST47

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi33 ↔ 77By similarity
Disulfide bondi44 ↔ 64By similarity
Disulfide bondi50 ↔ 71By similarity
Disulfide bondi54 ↔ 73By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ39182.

Expressioni

Tissue specificityi

Broadly expressed.2 Publications

Gene expression databases

GenevisibleiQ39182. AT.

Interactioni

Protein-protein interaction databases

BioGridi144. 1 interactor.
IntActiQ39182. 1 interactor.
STRINGi3702.AT2G02100.1.

Structurei

3D structure databases

ProteinModelPortaliQ39182.
SMRiQ39182.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DEFL family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410J2FQ. Eukaryota.
ENOG410YXD4. LUCA.
HOGENOMiHOG000238637.
InParanoidiQ39182.
OMAiEARICES.
OrthoDBiEOG09360Y66.
PhylomeDBiQ39182.

Family and domain databases

Gene3Di3.30.30.10. 1 hit.
InterProiIPR008176. Defensin_plant.
IPR003614. Scorpion_toxin-like.
[Graphical view]
PRINTSiPR00288. PUROTHIONIN.
SMARTiSM00505. Knot1. 1 hit.
[Graphical view]
SUPFAMiSSF57095. SSF57095. 1 hit.
PROSITEiPS00940. GAMMA_THIONIN. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q39182-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLSMRLISA VLIMFMIFVA TGMGPVTVEA RTCESQSHRF KGTCVSASNC
60 70
ANVCHNEGFV GGNCRGFRRR CFCTRHC
Length:77
Mass (Da):8,524
Last modified:November 1, 1996 - v1
Checksum:iEC04E660C3610965
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY803259 mRNA. Translation: AAX39300.1.
AY803262 mRNA. Translation: AAX39303.1.
X69139 mRNA. Translation: CAA48892.1.
AC005936 Genomic DNA. Translation: AAC97223.1.
CP002685 Genomic DNA. Translation: AEC05546.1.
AF370355 mRNA. Translation: AAK44170.1.
Z18455 mRNA. Translation: CAA79189.1.
PIRiS30578.
RefSeqiNP_178319.1. NM_126271.3.
UniGeneiAt.24172.

Genome annotation databases

EnsemblPlantsiAT2G02100.1; AT2G02100.1; AT2G02100.
GeneIDi814741.
GrameneiAT2G02100.1; AT2G02100.1; AT2G02100.
KEGGiath:AT2G02100.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY803259 mRNA. Translation: AAX39300.1.
AY803262 mRNA. Translation: AAX39303.1.
X69139 mRNA. Translation: CAA48892.1.
AC005936 Genomic DNA. Translation: AAC97223.1.
CP002685 Genomic DNA. Translation: AEC05546.1.
AF370355 mRNA. Translation: AAK44170.1.
Z18455 mRNA. Translation: CAA79189.1.
PIRiS30578.
RefSeqiNP_178319.1. NM_126271.3.
UniGeneiAt.24172.

3D structure databases

ProteinModelPortaliQ39182.
SMRiQ39182.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

BioGridi144. 1 interactor.
IntActiQ39182. 1 interactor.
STRINGi3702.AT2G02100.1.

Proteomic databases

PaxDbiQ39182.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G02100.1; AT2G02100.1; AT2G02100.
GeneIDi814741.
GrameneiAT2G02100.1; AT2G02100.1; AT2G02100.
KEGGiath:AT2G02100.

Organism-specific databases

TAIRiAT2G02100.

Phylogenomic databases

eggNOGiENOG410J2FQ. Eukaryota.
ENOG410YXD4. LUCA.
HOGENOMiHOG000238637.
InParanoidiQ39182.
OMAiEARICES.
OrthoDBiEOG09360Y66.
PhylomeDBiQ39182.

Miscellaneous databases

PROiQ39182.

Gene expression databases

GenevisibleiQ39182. AT.

Family and domain databases

Gene3Di3.30.30.10. 1 hit.
InterProiIPR008176. Defensin_plant.
IPR003614. Scorpion_toxin-like.
[Graphical view]
PRINTSiPR00288. PUROTHIONIN.
SMARTiSM00505. Knot1. 1 hit.
[Graphical view]
SUPFAMiSSF57095. SSF57095. 1 hit.
PROSITEiPS00940. GAMMA_THIONIN. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiDEF02_ARATH
AccessioniPrimary (citable) accession number: Q39182
Secondary accession number(s): Q42011, Q4VP00, Q4VP03
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1996
Last modified: November 30, 2016
This is version 116 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Caution

Was initially thought (Ref. 2) to be a protease inhibitor.Curated

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.