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Protein

Defensin-like protein 2

Gene

PDF2.2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Confers broad-spectrum resistance to pathogens.

Caution

Was initially thought (Ref. 2) to be a protease inhibitor.Curated

GO - Biological processi

  • defense response Source: TAIR
  • defense response to fungus Source: UniProtKB-KW
  • killing of cells of other organism Source: UniProtKB-KW

Keywordsi

Molecular functionAntimicrobial, Fungicide
Biological processPlant defense

Names & Taxonomyi

Protein namesi
Recommended name:
Defensin-like protein 2
Alternative name(s):
Low-molecular-weight cysteine-rich protein 69
Short name:
Protein LCR69
Plant defensin 2.2
Gene namesi
Name:PDF2.2
Synonyms:LCR69
Ordered Locus Names:At2g02100
ORF Names:F5O4.13
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

AraportiAT2G02100
TAIRilocus:2051668 AT2G02100

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 30Sequence analysisAdd BLAST30
ChainiPRO_000000702431 – 77Defensin-like protein 2Add BLAST47

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi33 ↔ 77By similarity
Disulfide bondi44 ↔ 64By similarity
Disulfide bondi50 ↔ 71By similarity
Disulfide bondi54 ↔ 73By similarity

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ39182
PRIDEiQ39182

Expressioni

Tissue specificityi

Broadly expressed.2 Publications

Gene expression databases

ExpressionAtlasiQ39182 baseline and differential
GenevisibleiQ39182 AT

Interactioni

Protein-protein interaction databases

BioGridi144, 1 interactor
IntActiQ39182, 1 interactor
STRINGi3702.AT2G02100.1

Structurei

3D structure databases

ProteinModelPortaliQ39182
SMRiQ39182
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the DEFL family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410J2FQ Eukaryota
ENOG410YXD4 LUCA
HOGENOMiHOG000238637
InParanoidiQ39182
OMAiLIMFMIF
OrthoDBiEOG09360Y66
PhylomeDBiQ39182

Family and domain databases

Gene3Di3.30.30.10, 1 hit
InterProiView protein in InterPro
IPR008176 Defensin_plant
IPR003614 Scorpion_toxin-like
IPR036574 Scorpion_toxin-like_sf
PRINTSiPR00288 PUROTHIONIN
SMARTiView protein in SMART
SM00505 Knot1, 1 hit
SUPFAMiSSF57095 SSF57095, 1 hit
PROSITEiView protein in PROSITE
PS00940 GAMMA_THIONIN, 1 hit

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q39182-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKLSMRLISA VLIMFMIFVA TGMGPVTVEA RTCESQSHRF KGTCVSASNC
60 70
ANVCHNEGFV GGNCRGFRRR CFCTRHC
Length:77
Mass (Da):8,524
Last modified:November 1, 1996 - v1
Checksum:iEC04E660C3610965
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY803259 mRNA Translation: AAX39300.1
AY803262 mRNA Translation: AAX39303.1
X69139 mRNA Translation: CAA48892.1
AC005936 Genomic DNA Translation: AAC97223.1
CP002685 Genomic DNA Translation: AEC05546.1
AF370355 mRNA Translation: AAK44170.1
Z18455 mRNA Translation: CAA79189.1
PIRiS30578
RefSeqiNP_178319.1, NM_126271.3
UniGeneiAt.24172

Genome annotation databases

EnsemblPlantsiAT2G02100.1; AT2G02100.1; AT2G02100
GeneIDi814741
GrameneiAT2G02100.1; AT2G02100.1; AT2G02100
KEGGiath:AT2G02100

Similar proteinsi

Entry informationi

Entry nameiDEF02_ARATH
AccessioniPrimary (citable) accession number: Q39182
Secondary accession number(s): Q42011, Q4VP00, Q4VP03
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1996
Last modified: May 23, 2018
This is version 123 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health