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Reviewed, UniProtKB/Swiss-Prot Q39172 (P1_ARATH)

Last modified February 9, 2010. Version 70. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Probable NADP-dependent oxidoreductase P1
    EC=1.3.1.74
Gene names
Name: P1
Ordered Locus Names: At5g16970
ORF Names: F2K13_120
OrganismArabidopsis thaliana (Mouse-ear cress) [Complete proteome]
Taxonomic identifier3702 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonscore eudicotyledonsrosidsmalvidsBrassicalesBrassicaceaeArabidopsis

Protein attributes

Sequence length345 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level.

General annotation (Comments)

Function

May play a distinct role in plant antioxidant defense and is possibly involved in NAD(P)/NAD(P)h homeostasis.

Catalytic activity

n-alkanal + NAD(P)+ = alk-2-enal + NAD(P)H.

Sequence similarities

Belongs to the NADP-dependent oxidoreductase L4BD family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 345345Probable NADP-dependent oxidoreductase P1
PRO_0000218073

Secondary structure

.............................................................. 345
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q39172-1 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 5AFCEBB2948B2680

FASTA34538,134
        10         20         30         40         50         60 
MTATNKQVIL KDYVSGFPTE SDFDFTTTTV ELRVPEGTNS VLVKNLYLSC DPYMRIRMGK 

        70         80         90        100        110        120 
PDPSTAALAQ AYTPGQPIQG YGVSRIIESG HPDYKKGDLL WGIVAWEEYS VITPMTHAHF 

       130        140        150        160        170        180 
KIQHTDVPLS YYTGLLGMPG MTAYAGFYEV CSPKEGETVY VSAASGAVGQ LVGQLAKMMG 

       190        200        210        220        230        240 
CYVVGSAGSK EKVDLLKTKF GFDDAFNYKE ESDLTAALKR CFPNGIDIYF ENVGGKMLDA 

       250        260        270        280        290        300 
VLVNMNMHGR IAVCGMISQY NLENQEGVHN LSNIIYKRIR IQGFVVSDFY DKYSKFLEFV 

       310        320        330        340 
LPHIREGKIT YVEDVADGLE KAPEALVGLF HGKNVGKQVV VVARE 

« Hide

References

« Hide 'large scale' references
[1]"Arabidopsis thaliana NADPH oxidoreductase homologs confer tolerance of yeasts toward the thiol-oxidizing drug diamide."
Babiychuk E., Kushnir S., Belles-Boix E., van Montagu M., Inze D.
J. Biol. Chem. 270:26224-26231(1995) [PubMed: 7592828] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Strain: cv. Columbia.
[2]"Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana."
Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E., Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M., Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K. expand/collapse author list , Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L., O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D., Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M., Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L., Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B., Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P., Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M., Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D., Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A., Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I., Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T., Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A., McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U., Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M., Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G., Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W., Bevan M., Fransz P.F.
Nature 408:823-826(2000) [PubMed: 11130714] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: cv. Columbia.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
Z49768 mRNA. Translation: CAA89838.1.
AL391141 Genomic DNA. Translation: CAC01710.1.
IPIIPI00542017.
PIRS57611.
RefSeqNP_197199.1.
UniGeneAt.22432

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
2J3HX-ray2.50A/B1-345[»]
2J3IX-ray2.80A/B1-345[»]
2J3JX-ray2.80A/B1-345[»]
2J3KX-ray2.80A/B1-345[»]
ModBaseSearch...

Proteomic databases

PRIDEQ39172.
ProMEXQ39172.

Genome annotation databases

GeneID831560.
GenomeReviewsGene locus AT5G16970 in contig BA000015_GR.
KEGGath:AT5G16970.

Organism-specific databases

TAIRAt5g16970.

Phylogenomic databases

eggNOGKOG1196.
HOGENOMHBG753318.
InParanoidQ39172.
OMARIRPLEN.
PhylomeDBQ39172.

Enzyme and pathway databases

BRENDA1.3.1.74. 302.

Gene expression databases

GenevestigatorQ39172.
GermOnlineAT5G16970. Arabidopsis thaliana.

Family and domain databases

InterProIPR002085. ADH_SF_Zn.
IPR013149. ADH_Zn-bd.
IPR011032. GroES-like.
IPR016040. NAD(P)-bd_dom.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PANTHERPTHR11695. ADH_Sf_Zn. 1 hit.
PfamPF00107. ADH_zinc_N. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameP1_ARATH
AccessionPrimary (citable) accession number: Q39172
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: February 9, 2010
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectPPAP (Plant Proteome Annotation Project)

Relevant documents

Arabidopsis thaliana

Arabidopsis thaliana: entries and gene names

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents