Reviewed, UniProtKB/Swiss-Prot Q390V3 (SURE1_BURS3)

Names and origin

Protein names

Recommended name:
    5'-nucleotidase surE 1
    EC=3.1.3.5
Alternative name(s):
    Nucleoside 5'-monophosphate phosphohydrolase 1

Gene names

Name:	surE1
Ordered Locus Names:	Bcep18194_B2902

Organism

Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194)) [Complete proteome] [HAMAP]

Taxonomic identifier

269483 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	259 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates By similarity.
Catalytic activity	A 5'-ribonucleotide + H2O = a ribonucleoside + phosphate. HAMAP MF_00060
Cofactor	Binds 1 divalent metal cation per subunit By similarity.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the surE nucleotidase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Ligand	Metal-binding Nucleotide-binding
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	5'-nucleotidase activity Inferred from electronic annotation. Source: HAMAP metal ion binding Inferred from electronic annotation. Source: HAMAP nucleotide binding Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 259	259	5'-nucleotidase surE 1 HAMAP MF_00060		PRO_0000235600
Sites
	Metal binding	16	1	Divalent metal cation By similarity
	Metal binding	17	1	Divalent metal cation By similarity
	Metal binding	48	1	Divalent metal cation By similarity
	Metal binding	101	1	Divalent metal cation By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q390V3-1 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: BEF47993BEEE0FA6	FASTA	259	27,869
	10 20 30 40 50 60 MQETRPLFDR VLLTNDDGID APGLDVLEQV ATQLAREVWI VAPAEDQSGT SHSLSLHEPL 70 80 90 100 110 120 RVHRKGDRRF AVRGTPGDCV AIAISHLMKD ARPDIVLSGV NRGGNLGTET VFSGTVGAAM 130 140 150 160 170 180 TSMLVGVPAI ALSQAFTDRN AVPWDTALAL APDVIRRLVA AGWDSDACLN VNFPPRPAQD 190 200 210 220 230 240 VRGLKVTNQG AGTLQGVEIV SGRDPRDIEY HWLKLARAPR DDDADSETVA LGEGYVAVTP 250 LKFERTHDQA LARLRTSLG

References

[1]

"Complete sequence of chromosome 2 of Burkholderia sp. 383." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P. Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000152 Genomic DNA. Translation: ABB13013.1.
RefSeq	YP_373657.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q390V3.
Genome annotation databases
GeneID	3754669.
GenomeReviews	Gene locus Bcep18194_B2902 in contig CP000152_GR.
KEGG	bur:Bcep18194_B2902.
NMPDR	fig|269483.3.peg.2987.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q390V3.
OMA	PGLWALA.
Enzyme and pathway databases
BioCyc	BSP36773:BCEP18194_B2902-MON.
Family and domain databases
HAMAP	MF_00060. [Tree]
InterPro	IPR002828. SurE-like_Pase/nucleotidase. [Graphical view]
Gene3D	G3DSA:3.40.1210.10. SurE-like_Pase/nucleotidase. 1 hit.
Pfam	PF01975. SurE. 1 hit. [Graphical view]
ProDom	PD005378. SurE. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR00087. surE. 1 hit.
ProtoNet	Search...

Entry information

Entry name

SURE1_BURS3

Accession

Primary (citable) accession number: Q390V3

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 16, 2006
Last sequence update:	November 22, 2005
Last modified:	November 3, 2009
This is version 28 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)