Reviewed, UniProtKB/Swiss-Prot Q390Q5 (MQO_BURS3)

Names and origin

Protein names

Recommended name:
    Probable malate:quinone oxidoreductase
    EC=1.1.99.16
Alternative name(s):
    Malate dehydrogenase [acceptor]
    MQO

Gene names

Name:	mqo
Ordered Locus Names:	Bcep18194_B2950

Organism

Burkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194)) [Complete proteome] [HAMAP]

Taxonomic identifier

269483 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length	553 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	(S)-malate + acceptor = oxaloacetate + reduced acceptor.
Cofactor	FAD By similarity.
Pathway	Carbohydrate metabolism; tricarboxylic acid cycle.
Sequence similarities	Belongs to the MQO family.

Ontologies

Keywords
Biological process	Tricarboxylic acid cycle
Ligand	FAD Flavoprotein
Molecular function	Oxidoreductase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	oxidation reduction Inferred from electronic annotation. Source: UniProtKB-KW tricarboxylic acid cycle Inferred from electronic annotation. Source: HAMAP
Molecular function	malate dehydrogenase (acceptor) activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 553	553	Probable malate:quinone oxidoreductase		PRO_0000325491

Sequences

	Sequence		Length	Mass (Da)
	Q390Q5-1 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: D38609F6EDF69809	FASTA	553	60,590
	10 20 30 40 50 60 MKKGSAVIKT LRVILSALAL CVATSSAHAA DTKKVDVLLV GGGIMSSTLG VWLHELQPDW 70 80 90 100 110 120 SMTMVERLDG VALESSNGWN NAGTGHSALA ELNYTPEKAD GKIDISKAIE INESFQISRQ 130 140 150 160 170 180 FWAWQVKQGV LKNPHSFINS TPHMSFVWGD DNVRFLKKRY EALQASPLFR GMQYSEDYDQ 190 200 210 220 230 240 IKQWVPLMME GRDPKQKVAA TWTPIGTDVN FGEITRQFVG YLKTQPNFTL SLSSEVREIS 250 260 270 280 290 300 RNADGTWHVS WVKLHSDEPA QSVDAKFVFI GAGGGALHLL QASGVPEAKD YGAFPVGGSF 310 320 330 340 350 360 LVTENPEVVK QHLAKAYGKA SVGSPPMSVP HLDTRIIDGK KIILFGPFAT FSTKFLKNGS 370 380 390 400 410 420 YFDLLKSTNT HNVAPMMRVG VDEFPLVQYL AGQLMLSDDD RFNALKEYFP NAKKEDWRLW 430 440 450 460 470 480 QAGQRVQIIK RDPVKGGVLK LGTEIVASQD GSIAGLLGAS PGASTAAPIM LNLMKKVFKD 490 500 510 520 530 540 KVATPEWQQK IRQIVPSYGT KLNDSPAKVV EEWTYTSDVL QLSPPPKIDV NTPSQATGTA 550 PARPAKASAD MAL

References

[1]

"Complete sequence of chromosome 2 of Burkholderia sp. 383." Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P. Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases
EMBLGenBankDDBJ	CP000152 Genomic DNA. Translation: ABB13061.1.
RefSeq	YP_373705.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	3754717.
GenomeReviews	Gene locus Bcep18194_B2950 in contig CP000152_GR.
KEGG	bur:Bcep18194_B2950.
NMPDR	fig|269483.3.peg.3035.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q390Q5.
Enzyme and pathway databases
BioCyc	BSP36773:BCEP18194_B2950-MON.
Family and domain databases
HAMAP	MF_00212. [Tree]
InterPro	IPR006231. Malate_quinone_OxRdtase. [Graphical view]
Pfam	PF06039. Mqo. 1 hit. [Graphical view]
TIGRFAMs	TIGR01320. mal_quin_oxido. 1 hit.
ProtoNet	Search...

Entry information

Entry name

MQO_BURS3

Accession

Primary (citable) accession number: Q390Q5

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 18, 2008
Last sequence update:	November 22, 2005
Last modified:	November 4, 2008
This is version 22 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)