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Q390Q5 (MQO_BURS3) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 42. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Probable malate:quinone oxidoreductase
EC=1.1.5.4
Alternative name(s):
MQO
Malate dehydrogenase [quinone]
Gene names
Name:mqo
Ordered Locus Names:Bcep18194_B2950
OrganismBurkholderia sp. (strain 383) (Burkholderia cepacia (strain ATCC 17760 / NCIB 9086 / R18194)) [Complete proteome] [HAMAP]
Taxonomic identifier269483 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Betaproteobacteria › Burkholderiales › Burkholderiaceae › Burkholderia › Burkholderia cepacia complex

Protein attributes

Sequence length553 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

(S)-malate + a quinone = oxaloacetate + reduced quinone. HAMAP MF_00212

Cofactor

FAD By similarity. HAMAP MF_00212

Pathway

Carbohydrate metabolism; tricarboxylic acid cycle; oxaloacetate from (S)-malate (quinone route): step 1/1. HAMAP MF_00212

Sequence similarities

Belongs to the MQO family.

Ontologies

Keywords
   Biological processTricarboxylic acid cycle
   LigandFAD
Flavoprotein
   Molecular functionOxidoreductase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processtricarboxylic acid cycle

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionmalate dehydrogenase (menaquinone) activity

Inferred from electronic annotation. Source: EC

malate dehydrogenase (quinone) activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 553553Probable malate:quinone oxidoreductase HAMAP MF_00212
PRO_0000325491

Sequences

Sequence LengthMass (Da)Tools
Q390Q5 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: D38609F6EDF69809

FASTA55360,590
        10         20         30         40         50         60 
MKKGSAVIKT LRVILSALAL CVATSSAHAA DTKKVDVLLV GGGIMSSTLG VWLHELQPDW 

        70         80         90        100        110        120 
SMTMVERLDG VALESSNGWN NAGTGHSALA ELNYTPEKAD GKIDISKAIE INESFQISRQ 

       130        140        150        160        170        180 
FWAWQVKQGV LKNPHSFINS TPHMSFVWGD DNVRFLKKRY EALQASPLFR GMQYSEDYDQ 

       190        200        210        220        230        240 
IKQWVPLMME GRDPKQKVAA TWTPIGTDVN FGEITRQFVG YLKTQPNFTL SLSSEVREIS 

       250        260        270        280        290        300 
RNADGTWHVS WVKLHSDEPA QSVDAKFVFI GAGGGALHLL QASGVPEAKD YGAFPVGGSF 

       310        320        330        340        350        360 
LVTENPEVVK QHLAKAYGKA SVGSPPMSVP HLDTRIIDGK KIILFGPFAT FSTKFLKNGS 

       370        380        390        400        410        420 
YFDLLKSTNT HNVAPMMRVG VDEFPLVQYL AGQLMLSDDD RFNALKEYFP NAKKEDWRLW 

       430        440        450        460        470        480 
QAGQRVQIIK RDPVKGGVLK LGTEIVASQD GSIAGLLGAS PGASTAAPIM LNLMKKVFKD 

       490        500        510        520        530        540 
KVATPEWQQK IRQIVPSYGT KLNDSPAKVV EEWTYTSDVL QLSPPPKIDV NTPSQATGTA 

       550 
PARPAKASAD MAL

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References

[1]"Complete sequence of chromosome 2 of Burkholderia sp. 383."
US DOE Joint Genome Institute
Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T., Hammon N., Israni S., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Kyrpides N., Lykidis A., Richardson P.
Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 383.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CP000152 Genomic DNA. Translation: ABB13061.1.
RefSeqYP_373705.1. NC_007511.1.

3D structure databases

ProteinModelPortalQ390Q5.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ390Q5.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3754717.
GenomeReviewsGene locus Bcep18194_B2950 in contig CP000152_GR.
KEGGbur:Bcep18194_B2950.
NMPDRfig|269483.3.peg.3035.
PATRIC19296878. VBIBurSp120713_7798.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0579.
HOGENOMHBG289663.
OMAKKWVPLM.
ProtClustDBPRK05257.

Enzyme and pathway databases

BioCycBSP36773:BCEP18194_B2950-MONOMER.

Family and domain databases

HAMAPMF_00212. MQO.
[Tree]
InterProIPR006231. Malate_quinone_OxRdtase.
[Graphical view]
KOK00116.
PANTHERPTHR13847:SF14. PTHR13847:SF14. 1 hit.
PfamPF06039. Mqo. 1 hit.
[Graphical view]
TIGRFAMsTIGR01320. Mal_quin_oxido. 1 hit.
ProtoNetSearch...

Entry information

Entry nameMQO_BURS3
AccessionPrimary (citable) accession number: Q390Q5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: November 22, 2005
Last modified: January 25, 2012
This is version 42 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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