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Protein

Protein UNUSUAL FLORAL ORGANS

Gene

UFO

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). Considered as a meristem identity factor required for normal growth of the young floral meristem. Acts together with LEAFY to positively regulate the B class floral homeotic genes APETALA3 and PISTILLATA. In this way, operates as a region-specific regulator for petal and stamen development. Alternatively, may play a role as a negative regulator of the C class floral homeotic genes. Interacts together with the SKP1-like protein ASK1 to form a ubiquitin E3 ligase complex and could indirectly promote the ubiquitination and degradation of specific proteins controlling the floral primordia development like repressors of B class floral homeotic genes.By similarity3 Publications

Miscellaneous

Mutations in the UFO gene result in the formation of unusual floral organs.

Pathwayi: protein ubiquitination

This protein is involved in the pathway protein ubiquitination, which is part of Protein modification.
View all proteins of this organism that are known to be involved in the pathway protein ubiquitination and in Protein modification.

GO - Molecular functioni

  • transcription factor binding Source: TAIR
  • ubiquitin-protein transferase activity Source: TAIR

GO - Biological processi

  • cell differentiation Source: UniProtKB-KW
  • flower development Source: UniProtKB-KW
  • regulation of transcription, DNA-templated Source: TAIR
  • SCF-dependent proteasomal ubiquitin-dependent protein catabolic process Source: TAIR
  • transcription, DNA-templated Source: UniProtKB-KW

Keywordsi

Molecular functionActivator, Developmental protein
Biological processDifferentiation, Flowering, Transcription, Transcription regulation, Ubl conjugation pathway

Enzyme and pathway databases

UniPathwayiUPA00143

Names & Taxonomyi

Protein namesi
Recommended name:
Protein UNUSUAL FLORAL ORGANS
Alternative name(s):
F-box only protein 1
Short name:
AtFBX1
Gene namesi
Name:UFO
Synonyms:FBX1
Ordered Locus Names:At1g30950
ORF Names:F17F8.16
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G30950
TAIRilocus:2015766 AT1G30950

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001199661 – 442Protein UNUSUAL FLORAL ORGANSAdd BLAST442

Proteomic databases

PaxDbiQ39090
PRIDEiQ39090

Expressioni

Developmental stagei

Detected early throughout the shoot apical meristem, but not in the emerging leaf primordia. Restricted later to the junction between sepal and petal primordia.1 Publication

Gene expression databases

ExpressionAtlasiQ39090 differential
GenevisibleiQ39090 AT

Interactioni

Subunit structurei

Part of a putative SCF (ASK/Cullin/F-box) ubiquitin ligase complex. Interacts with SKP1A/ASK1, SKP1B/ASK2 and ASK11.3 Publications

Binary interactionsi

Show more details

GO - Molecular functioni

  • transcription factor binding Source: TAIR

Protein-protein interaction databases

BioGridi25217, 15 interactors
IntActiQ39090, 15 interactors
STRINGi3702.AT1G30950.1

Structurei

3D structure databases

ProteinModelPortaliQ39090
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini44 – 90F-boxPROSITE-ProRule annotationAdd BLAST47

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni1 – 85Interaction with SKP1A1 PublicationAdd BLAST85

Domaini

The F-box is necessary for the interaction with ASK proteins.By similarity

Phylogenomic databases

eggNOGiENOG410IGS3 Eukaryota
ENOG410ZZPZ LUCA
HOGENOMiHOG000084155
InParanoidiQ39090
OMAiMDPRVWR
OrthoDBiEOG09360FMD
PhylomeDBiQ39090

Family and domain databases

Gene3Di3.80.10.10, 1 hit
InterProiView protein in InterPro
IPR036047 F-box-like_dom_sf
IPR001810 F-box_dom
IPR015915 Kelch-typ_b-propeller
IPR032675 LRR_dom_sf
PfamiView protein in Pfam
PF00646 F-box, 1 hit
SMARTiView protein in SMART
SM00256 FBOX, 1 hit
SUPFAMiSSF117281 SSF117281, 1 hit
SSF81383 SSF81383, 1 hit
PROSITEiView protein in PROSITE
PS50181 FBOX, 1 hit

Sequencei

Sequence statusi: Complete.

Q39090-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSTVFINNP SLTLPFSYTF TSSSNSSTTT STTTDSSSGQ WMDGRIWSKL
60 70 80 90 100
PPPLLDRVIA FLPPPAFFRT RCVCKRFYSL LFSNTFLETY LQLLPLRHNC
110 120 130 140 150
FLFFKHKTLK SYIYKRGGTN DDDSNKAEGF LFDPNEIRWY RLSFAYIPSG
160 170 180 190 200
FYPSGSSGGL VSWVSEEAGL KTILLCNPLV GSVSQLPPIS RPRLFPSIGL
210 220 230 240 250
SVTPTSIDVT VAGDDLISPY AVKNLSSESF HVDAGGFFSL WAMTSSLPRL
260 270 280 290 300
CSLESGKMVY VQGKFYCMNY SPFSVLSYEV TGNRWIKIQA PMRRFLRSPS
310 320 330 340 350
LLESKGRLIL VAAVEKSKLN VPKSLRLWSL QQDNATWVEI ERMPQPLYTQ
360 370 380 390 400
FAAEEGGKGF ECVGNQEFVM IVLRGTSLQL LFDIVRKSWL WVPPCPYSGS
410 420 430 440
GGGSSGGGSD GEVLQGFAYD PVLTTPVVSL LDQLTLPFPG VC
Length:442
Mass (Da):49,047
Last modified:May 9, 2003 - v2
Checksum:i6E5C38B0F92AE8B7
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti44G → C in CAA61508 (PubMed:8589630).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
X89224 Genomic DNA Translation: CAA61508.1
AC000107 Genomic DNA Translation: AAF98199.1
CP002684 Genomic DNA Translation: AEE31296.1
DQ056469 mRNA Translation: AAY78626.1
PIRiS57710
RefSeqiNP_564368.1, NM_102834.2
UniGeneiAt.51845

Genome annotation databases

EnsemblPlantsiAT1G30950.1; AT1G30950.1; AT1G30950
GeneIDi839982
GrameneiAT1G30950.1; AT1G30950.1; AT1G30950
KEGGiath:AT1G30950

Similar proteinsi

Entry informationi

Entry nameiUFO_ARATH
AccessioniPrimary (citable) accession number: Q39090
Secondary accession number(s): Q4PT17, Q9FYI4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 9, 2003
Last sequence update: May 9, 2003
Last modified: May 23, 2018
This is version 138 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways

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