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Protein

Transcription factor CAULIFLOWER

Gene

CAL

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Probable transcription factor that promotes early floral meristem identity in synergy with APETALA1, FRUITFULL and LEAFY. Is required subsequently for the transition of an inflorescence meristem into a floral meristem. Seems to be partially redundant to the function of APETALA1. Positively regulates the APETALA1 and LEAFY expression.2 Publications

Miscellaneous

Mutations in the CAL gene result in a characteristic proliferation of inflorescence meristems in place of floral meristems. The fragment expressed in cal-5 mutant is homolog to the CAL proteins present in Brassica oleracea var. botrytis and may thus explain the 'cauliflower'-shaped floral meristem (PubMed:7824951).1 Publication

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionActivator, Developmental protein, DNA-binding
Biological processDifferentiation, Flowering, Transcription, Transcription regulation

Names & Taxonomyi

Protein namesi
Recommended name:
Transcription factor CAULIFLOWER
Short name:
AtCAL
Alternative name(s):
Agamous-like MADS-box protein AGL10
Gene namesi
Name:CAL
Synonyms:AGL10
Ordered Locus Names:At1g26310
ORF Names:F28B23.24
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 1

Organism-specific databases

AraportiAT1G26310
TAIRilocus:2028830 AT1G26310

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Nucleus

Pathology & Biotechi

Mutagenesis

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Mutagenesisi27G → D in cal-3; no visible phenotype. 'Cauliflower' shape when associated with AP1 disruption. 1 Publication1
Mutagenesisi39C → Y in cal-2; no visible phenotype. 'Cauliflower' shape when associated with AP1 disruption. 1 Publication1
Mutagenesisi131E → K in cal-4; no visible phenotype. 'Cauliflower' shape when associated with AP1 disruption. 1 Publication1
Mutagenesisi151 – 255Missing in cal-5; 'Cauliflower' shape. 1 PublicationAdd BLAST105
Mutagenesisi176 – 186ERENILRTKQT → KRENILRTRQI in cal-1; no visible phenotype. 'Cauliflower' shape when associated with AP1 disruption. 1 PublicationAdd BLAST11

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001994801 – 255Transcription factor CAULIFLOWERAdd BLAST255

Proteomic databases

PaxDbiQ39081
PRIDEiQ39081

Expressioni

Tissue specificityi

Expressed in young flower primordia.

Developmental stagei

Expressed at an early stage of floral initiation.

Gene expression databases

ExpressionAtlasiQ39081 baseline and differential
GenevisibleiQ39081 AT

Interactioni

Subunit structurei

Homodimer capable of binding to CArG-box sequences.By similarity

Binary interactionsi

WithEntry#Exp.IntActNotes
SOC1O646454EBI-592136,EBI-592041

GO - Molecular functioni

Protein-protein interaction databases

BioGridi24408, 5 interactors
DIPiDIP-33764N
IntActiQ39081, 6 interactors
STRINGi3702.AT1G26310.1

Structurei

3D structure databases

ProteinModelPortaliQ39081
SMRiQ39081
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 61MADS-boxPROSITE-ProRule annotationAdd BLAST61
Domaini90 – 180K-boxPROSITE-ProRule annotationAdd BLAST91

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili90 – 198Sequence analysisAdd BLAST109

Keywords - Domaini

Coiled coil

Phylogenomic databases

eggNOGiKOG0014 Eukaryota
COG5068 LUCA
InParanoidiQ39081
KOiK09264
OMAiNWSMEYS
OrthoDBiEOG09360OG3
PhylomeDBiQ39081

Family and domain databases

CDDicd00265 MADS_MEF2_like, 1 hit
Gene3Di3.40.1810.10, 1 hit
InterProiView protein in InterPro
IPR033896 MADS_MEF2-like
IPR002487 TF_Kbox
IPR002100 TF_MADSbox
IPR036879 TF_MADSbox_sf
PfamiView protein in Pfam
PF01486 K-box, 1 hit
PF00319 SRF-TF, 1 hit
PRINTSiPR00404 MADSDOMAIN
SMARTiView protein in SMART
SM00432 MADS, 1 hit
SUPFAMiSSF55455 SSF55455, 1 hit
PROSITEiView protein in PROSITE
PS51297 K_BOX, 1 hit
PS00350 MADS_BOX_1, 1 hit
PS50066 MADS_BOX_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q39081-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGRGRVELKR IENKINRQVT FSKRRTGLLK KAQEISVLCD AEVSLIVFSH
60 70 80 90 100
KGKLFEYSSE SCMEKVLERY ERYSYAERQL IAPDSHVNAQ TNWSMEYSRL
110 120 130 140 150
KAKIELLERN QRHYLGEELE PMSLKDLQNL EQQLETALKH IRSRKNQLMN
160 170 180 190 200
ESLNHLQRKE KEIQEENSML TKQIKERENI LRTKQTQCEQ LNRSVDDVPQ
210 220 230 240 250
PQPFQHPHLY MIAHQTSPFL NMGGLYQEED QTAMRRNNLD LTLEPIYNYL

GCYAA
Length:255
Mass (Da):30,187
Last modified:September 22, 2009 - v3
Checksum:i5F7313A804DF594D
GO

Sequence cautioni

The sequence AAA64789 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAC67505 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAC67506 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAC67507 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAC67508 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAC67509 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAC67510 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAC67511 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAC67512 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAC67513 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAC67514 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAC67515 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAC67516 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAC67517 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAC67518 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAC67519 differs from that shown. Reason: Erroneous gene model prediction.Curated
The sequence AAG50679 differs from that shown. Reason: Erroneous gene model prediction.Curated

Natural variant

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Natural varianti78R → S in strain: cv. Kas-0. 1
Natural varianti114Y → H in strain: cv. Bu-0. 1
Natural varianti120E → G in strain: cv. Bretagny. 1
Natural varianti122M → K in strain: cv. Kas-0. 1
Natural varianti141I → T in strain: cv. Bu-0. 1
Natural varianti161K → E in strain: cv. Kent. 1
Natural varianti176E → K in strain: cv. Kent and cv. Wassilewskija. 1
Natural varianti182R → K in strain: cv. Bu-0, cv. Landsberg erecta, cv. Li-8 and cv. NL2. 1
Natural varianti184K → R in strain: cv. NL2. 1
Natural varianti186T → I in strain: cv. Wassilewskija. 1
Natural varianti195V → I in strain: cv. Co-1. 1
Natural varianti196D → N in strain: cv. Kent. 1
Natural varianti205Q → QL in strain: cv. Bu-2. 1
Natural varianti209L → F in strain: cv. Li-3. 1
Natural varianti228E → G in strain: cv. Bla-1, cv. Bretagny, cv. Bs-0, cv. Bu-0, cv. Bu-2, cv. Co-1, cv. Kas-0, cv. Kent, cv. Landsberg erecta, cv. Li-3, cv. Li-8, cv. Nd-0, cv. NL2 and cv. Wassilewskija. 1
Natural varianti238N → D in strain: cv. Bu-2. 1
Natural varianti249Y → C in strain: cv. NL2. 1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
L36925 Genomic DNA Translation: AAA64789.1 Sequence problems.
AC079829 Genomic DNA Translation: AAG50679.1 Sequence problems.
CP002684 Genomic DNA Translation: AEE30674.1
AB493477 mRNA Translation: BAH30315.1
AF061401 Genomic DNA Translation: AAC67505.1 Sequence problems.
AF061402 Genomic DNA Translation: AAC67506.1 Sequence problems.
AF061403 Genomic DNA Translation: AAC67507.1 Sequence problems.
AF061404 Genomic DNA Translation: AAC67508.1 Sequence problems.
AF061405 Genomic DNA Translation: AAC67509.1 Sequence problems.
AF061406 Genomic DNA Translation: AAC67510.1 Sequence problems.
AF061407 Genomic DNA Translation: AAC67511.1 Sequence problems.
AF061408 Genomic DNA Translation: AAC67512.1 Sequence problems.
AF061409 Genomic DNA Translation: AAC67513.1 Sequence problems.
AF061410 Genomic DNA Translation: AAC67514.1 Sequence problems.
AF061411 Genomic DNA Translation: AAC67515.1 Sequence problems.
AF061412 Genomic DNA Translation: AAC67516.1 Sequence problems.
AF061413 Genomic DNA Translation: AAC67517.1 Sequence problems.
AF061414 Genomic DNA Translation: AAC67518.1 Sequence problems.
AF061415 Genomic DNA Translation: AAC67519.1 Sequence problems.
PIRiE86389
RefSeqiNP_564243.1, NM_102395.3
UniGeneiAt.41269

Genome annotation databases

EnsemblPlantsiAT1G26310.1; AT1G26310.1; AT1G26310
GeneIDi839172
GrameneiAT1G26310.1; AT1G26310.1; AT1G26310
KEGGiath:AT1G26310

Keywords - Coding sequence diversityi

Polymorphism

Similar proteinsi

Entry informationi

Entry nameiCAL_ARATH
AccessioniPrimary (citable) accession number: Q39081
Secondary accession number(s): C0SUX4
, Q9C675, Q9S779, Q9S780, Q9SBG8, Q9SBG9, Q9SBH0, Q9SBH1, Q9SBH2, Q9SBH3, Q9SBH4, Q9SBH5, Q9SBH6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 9, 2003
Last sequence update: September 22, 2009
Last modified: April 25, 2018
This is version 132 of the entry and version 3 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health