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Protein

Cyclin-B2-2

Gene

CYCB2-2

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Keywordsi

Molecular functionCyclin
Biological processCell cycle, Cell division

Enzyme and pathway databases

ReactomeiR-ATH-176408 Regulation of APC/C activators between G1/S and early anaphase
R-ATH-2299718 Condensation of Prophase Chromosomes
R-ATH-2500257 Resolution of Sister Chromatid Cohesion
R-ATH-4419969 Depolymerisation of the Nuclear Lamina
R-ATH-6804114 TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest
R-ATH-69273 Cyclin A/B1/B2 associated events during G2/M transition
R-ATH-69478 G2/M DNA replication checkpoint
R-ATH-75035 Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex

Names & Taxonomyi

Protein namesi
Recommended name:
Cyclin-B2-2
Alternative name(s):
Cyc2b-At
Cyclin-2b
G2/mitotic-specific cyclin-B2-2
Short name:
CycB2;2
Gene namesi
Name:CYCB2-2
Synonyms:CYC2B
Ordered Locus Names:At4g35620
ORF Names:F8D20.130
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 4

Organism-specific databases

AraportiAT4G35620
TAIRilocus:2127948 AT4G35620

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Chloroplast Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertion Graphics by Christian Stolte; Source: COMPARTMENTS

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002870131 – 429Cyclin-B2-2Add BLAST429

Proteomic databases

PaxDbiQ39070

Expressioni

Tissue specificityi

Expressed in roots.1 Publication

Gene expression databases

ExpressionAtlasiQ39070 baseline and differential
GenevisibleiQ39070 AT

Interactioni

Subunit structurei

Interacts with CDC20-1 and CDC20-2.1 Publication

Protein-protein interaction databases

BioGridi14996, 15 interactors
IntActiQ39070, 10 interactors
STRINGi3702.AT4G35620.1

Structurei

3D structure databases

ProteinModelPortaliQ39070
SMRiQ39070
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the cyclin family. Cyclin AB subfamily.Curated

Phylogenomic databases

eggNOGiKOG0653 Eukaryota
COG5024 LUCA
HOGENOMiHOG000167672
InParanoidiQ39070
KOiK21777
OMAiQFDITDK
OrthoDBiEOG09360JD9
PhylomeDBiQ39070

Family and domain databases

CDDicd00043 CYCLIN, 2 hits
InterProiView protein in InterPro
IPR013763 Cyclin-like
IPR036915 Cyclin-like_sf
IPR004367 Cyclin_C-dom
IPR006671 Cyclin_N
PfamiView protein in Pfam
PF02984 Cyclin_C, 1 hit
PF00134 Cyclin_N, 1 hit
SMARTiView protein in SMART
SM00385 CYCLIN, 2 hits
SM01332 Cyclin_C, 1 hit
SUPFAMiSSF47954 SSF47954, 2 hits
PROSITEiView protein in PROSITE
PS00292 CYCLINS, 1 hit

Sequencei

Sequence statusi: Complete.

Q39070-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVNPEENNRN LVVKPITEIL QDDDKRSRKF GVEMKRQNRR ALGVINHNLV
60 70 80 90 100
GAKAYPCVVN KRRGLSQRKQ ESCDKKKLDS LHPSISRSQE ETKKLKPSGN
110 120 130 140 150
EFGDCIFIDE EEEKNEEVTL DQPMPMSLEE PYIEFDPMEE EVEMEDMEEE
160 170 180 190 200
QEEPVLDIDE YDANNSLAAV EYVQDLYDFY RKTERFSCVP LDYMAQQFDI
210 220 230 240 250
SDKMRAILID WLIEVHDKFE LMNETLFLTV NLIDRFLSKQ AVARKKLQLV
260 270 280 290 300
GLVALLLACK YEEVSVPIVE DLVVISDKAY TRTDVLEMEK IMLSTLQFNM
310 320 330 340 350
SLPTQYPFLK RFLKAAQSDK KLEILASFLI ELALVDYEMV RYPPSLLAAT
360 370 380 390 400
AVYTAQCTIH GFSEWNSTCE FHCHYSENQL LECCRRMVRL HQKAGTDKLT
410 420
GVHRKYSSSK FGYIATKYEA AHFLVSDSH
Length:429
Mass (Da):49,787
Last modified:May 15, 2007 - v2
Checksum:i5BDE8D7171A2FE09
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Sequence conflicti160E → G in CAA83276 (PubMed:7972055).Curated1
Sequence conflicti383C → R in CAA83276 (PubMed:7972055).Curated1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
Z31401 mRNA Translation: CAA83276.1
AL031135 Genomic DNA Translation: CAA20032.1
AL161587 Genomic DNA Translation: CAB80278.1
CP002687 Genomic DNA Translation: AEE86541.1
AK226721 mRNA Translation: BAE98826.1
PIRiT04667
RefSeqiNP_195287.1, NM_119727.4
UniGeneiAt.26

Genome annotation databases

EnsemblPlantsiAT4G35620.1; AT4G35620.1; AT4G35620
GeneIDi829714
GrameneiAT4G35620.1; AT4G35620.1; AT4G35620
KEGGiath:AT4G35620

Similar proteinsi

Entry informationi

Entry nameiCCB22_ARATH
AccessioniPrimary (citable) accession number: Q39070
Secondary accession number(s): O81794
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 15, 2007
Last sequence update: May 15, 2007
Last modified: April 25, 2018
This is version 113 of the entry and version 2 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
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Main funding by: National Institutes of Health