Q38ZH8 (GPMA1_LACSS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 1
Short name=BPG-dependent PGAM 1
Short name=PGAM 1
Short name=Phosphoglyceromutase 1
Short name=dPGM 1
EC=5.4.2.1

Gene names

Name:	gpmA1
Ordered Locus Names:	LCA_0100

Organism

Lactobacillus sakei subsp. sakei (strain 23K) [Complete proteome] [HAMAP]

Taxonomic identifier

314315 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	235 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate By similarity. HAMAP MF_01039
Catalytic activity	2-phospho-D-glycerate = 3-phospho-D-glycerate. HAMAP MF_01039
Pathway	Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5. HAMAP MF_01039
Sequence similarities	Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.

Ontologies

Keywords
Biological process	Glycolysis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	phosphoglycerate mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 235	235	2,3-bisphosphoglycerate-dependent phosphoglycerate mutase 1 HAMAP MF_01039		PRO_0000229124
Sites
	Active site	9	1	Tele-phosphohistidine intermediate By similarity
	Active site	177	1	By similarity
	Site	60	1	Interaction with carboxyl group of phosphoglycerates By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q38ZH8 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: 307C4318329F15C2	FASTA	235	26,436
	10 20 30 40 50 60 MANLVIVRHG ESVANQLKTY TGWSDVALTA KGRQQAHQVG RQIKDAGFQF SHVHTSLLKR 70 80 90 100 110 120 AILTSYIVLE ELDQLALPMT KSWRLNERHY GALRGLNKDT TRTIFGVHQV ARWRRSYTAL 130 140 150 160 170 180 PPLLIRSSTA RRYRLVPRKS RPRGESLAQA TQRLLPYWQD QVVPGLLAGQ DQLIVAHGST 190 200 210 220 230 LRALIKVIEQ ISDQAIDGVE VANGEALYYQ FGTDLTVLKK GRLALGSETD EEKEN

References

[1]

"The complete genome sequence of the meat-borne lactic acid bacterium Lactobacillus sakei 23K." Chaillou S., Champomier-Verges M.-C., Cornet M., Crutz-Le Coq A.-M., Dudez A.-M., Martin V., Beaufils S., Darbon-Rongere E., Bossy R., Loux V., Zagorec M. Nat. Biotechnol. 23:1527-1533(2005) [PubMed: 16273110] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 23K.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR936503 Genomic DNA. Translation: CAI54399.1.
RefSeq	YP_394711.1. NC_007576.1.
3D structure databases
ProteinModelPortal	Q38ZH8.
ModBase	Search...
Protein-protein interaction databases
STRING	Q38ZH8.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3778668.
GenomeReviews	Gene locus LCA_0100 in contig CR936503_GR.
KEGG	lsa:LSA0100.
PATRIC	22272968. VBILacSak116432_0097.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0588.
HOGENOM	HBG658938.
OMA	ESTANRD.
PhylomeDB	Q38ZH8.
Enzyme and pathway databases
BioCyc	LSAK314315:LSA0100-MONOMER.
Family and domain databases
HAMAP	MF_01039. PGAM_GpmA. [Tree]
InterPro	IPR013078. His_Pase_superF_clade-1. IPR001345. PG/BPGM_mutase_AS. IPR005952. Phosphogly_mut1. [Graphical view]
KO	K01834.
PANTHER	PTHR11931. Phosphogly_mut1. 1 hit.
Pfam	PF00300. His_Phos_1. 1 hit. [Graphical view]
SMART	SM00855. PGAM. 1 hit. [Graphical view]
TIGRFAMs	TIGR01258. Pgm_1. 1 hit.
PROSITE	PS00175. PG_MUTASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GPMA1_LACSS

Accession

Primary (citable) accession number: Q38ZH8

Entry history

Integrated into UniProtKB/Swiss-Prot:	April 4, 2006
Last sequence update:	November 22, 2005
Last modified:	January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program