Q38YS5 (GCP_LACSS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	LCA_0351

Organism

Lactobacillus sakei subsp. sakei (strain 23K) [Complete proteome] [HAMAP]

Taxonomic identifier

314315 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus › Lactobacillus sakei › Lactobacillus sakei subsp. sakei

Protein attributes

Sequence length	344 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP-Rule MF_01445
Subcellular location	Cytoplasm Potential HAMAP-Rule MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	threonylcarbamoyladenosine biosynthetic process Inferred from electronic annotation. Source: HAMAP
Cellular_component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular_function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 344	344	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP-Rule MF_01445		PRO_0000303397

Sequences

	Sequence		Length	Mass (Da)
	Q38YS5 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: 092FB9919050EE2D	FASTA	344	36,536
	10 20 30 40 50 60 MTEKKELILA FESSCDETSV AVIENGQRIL SNVIATQIKS HQRFGGVVPE VASRHHVEQI 70 80 90 100 110 120 TLCTQEALEQ AGVTYDDLTA VAVTYGPGLV GALLIGVTAA KAIAYAHHLP LVPVNHMAGH 130 140 150 160 170 180 IYAARFVKPL EYPLLALLVS GGHTELVYMP AAGQFEIIGD TRDDAAGEAY DKIGRVLGVP 190 200 210 220 230 240 YPAGKEIDRL AHLGQDTFNF PRAMLKEDNL DFSFSGLKSA FINTVHHADQ IGETLDQADL 250 260 270 280 290 300 AASFQASVVE VLVTKTLRAA QSLKVKQLVV AGGVAANQGL REGLAAGIES AGLDLDLIMP 310 320 330 340 PLRLCGDNGA MIGAAAHIAL AQNTLADLDL NAIPSLDFPY QNEL

References

[1]

"The complete genome sequence of the meat-borne lactic acid bacterium Lactobacillus sakei 23K." Chaillou S., Champomier-Verges M.-C., Cornet M., Crutz-Le Coq A.-M., Dudez A.-M., Martin V., Beaufils S., Darbon-Rongere E., Bossy R., Loux V., Zagorec M. Nat. Biotechnol. 23:1527-1533(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 23K.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR936503 Genomic DNA. Translation: CAI54652.1.
RefSeq	YP_394964.1. NC_007576.1.
3D structure databases
ProteinModelPortal	Q38YS5.
ModBase	Search...
Protein-protein interaction databases
STRING	314315.LSA0351.
Protein family/group databases
MEROPS	M22.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAI54652; CAI54652; LCA_0351.
GeneID	3778789.
KEGG	lsa:LSA0351.
PATRIC	22273470. VBILacSak116432_0343.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0533.
KO	K01409.
OMA	AVHHMEG.
ProtClustDB	PRK09604.
Family and domain databases
HAMAP	MF_01445. gcp.
InterPro	IPR000905. Gcp-like_dom. IPR017861. KAE1/YgjD. IPR017860. Peptidase_M22_CS. IPR022450. T6A_Gcp_(YgjD). [Graphical view]
PANTHER	PTHR11735:SF6. PTHR11735:SF6. 1 hit.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. bact_gcp. 1 hit. TIGR00329. gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_LACSS

Accession

Primary (citable) accession number: Q38YS5

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	November 22, 2005
Last modified:	May 1, 2013
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program