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Q38Y20 (PGK_LACSS) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 58. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Phosphoglycerate kinase

EC=2.7.2.3
Gene names
Name:pgk
Ordered Locus Names:LCA_0605
OrganismLactobacillus sakei subsp. sakei (strain 23K) [Complete proteome] [HAMAP]
Taxonomic identifier314315 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

Protein attributes

Sequence length404 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm Potential HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 404404Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_1000009626

Regions

Nucleotide binding360 – 3634ATP By similarity
Region22 – 243Substrate binding By similarity
Region60 – 634Substrate binding By similarity

Sites

Binding site371Substrate By similarity
Binding site1201Substrate By similarity
Binding site1601Substrate By similarity
Binding site2151ATP By similarity
Binding site3331ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q38Y20 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: FB5AAFF55D17067B

FASTA40442,727
        10         20         30         40         50         60 
MAKQTVADLK DIKGKKVLVR VDFNVPIKGG VIGDDNRIVA ALPTIQYIID NGGKAILLSH 

        70         80         90        100        110        120 
LGRIKSDEDK KELTLKPVAA RLGELLNKDV AFVASNEGQE LEDAINAMTD GQVLVMENTR 

       130        140        150        160        170        180 
FQDIDNDFGK RESKNDPKLG EYWASLGDMF VNDAFGTAHR AHASNVGIAT AMKANNKPAV 

       190        200        210        220        230        240 
AGYLLEKEIK FLGEAVDAPE RPFVAILGGA KVSDKIGVIE HLLAKADKVI VGGGMTYTFY 

       250        260        270        280        290        300 
AAKGLSIGNS LVEEDKIELA KELIEKAGDK LVLPVDNVVA DAFSNDAKTE TVEGNIPDGY 

       310        320        330        340        350        360 
MALDIGPKAI ADFENVLKDA KTVVWNGPMG VFEMDNFAKG TLAIGEFLGN LSGATTIVGG 

       370        380        390        400 
GDSTAAVKKL GVGDKLTHIS TGGGASLEYL EGKTLPGIAA ISDK 

« Hide

References

[1]"The complete genome sequence of the meat-borne lactic acid bacterium Lactobacillus sakei 23K."
Chaillou S., Champomier-Verges M.-C., Cornet M., Crutz-Le Coq A.-M., Dudez A.-M., Martin V., Beaufils S., Darbon-Rongere E., Bossy R., Loux V., Zagorec M.
Nat. Biotechnol. 23:1527-1533(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 23K.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR936503 Genomic DNA. Translation: CAI54909.1.
RefSeqYP_395220.1. NC_007576.1.

3D structure databases

ProteinModelPortalQ38Y20.
SMRQ38Y20. Positions 3-404.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING314315.LSA0605.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAI54909; CAI54909; LCA_0605.
GeneID3776983.
KEGGlsa:LSA0605.
PATRIC22274030. VBILacSak116432_0584.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0126.
KOK00927.
OMAWEALDIG.
OrthoDBEOG64N9Z0.

Enzyme and pathway databases

UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_LACSS
AccessionPrimary (citable) accession number: Q38Y20
Entry history
Integrated into UniProtKB/Swiss-Prot: January 15, 2008
Last sequence update: November 22, 2005
Last modified: June 11, 2014
This is version 58 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways