Q38VS4 (Q38VS4_LACSS) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
DNA polymerase RuleBase RU004460
EC=2.7.7.7 RuleBase RU004460

Gene names

Name:	polA EMBL CAI55709.1
Ordered Locus Names:	LCA_1406 EMBL CAI55709.1

Organism

Lactobacillus sakei subsp. sakei (strain 23K) [Complete proteome] [HAMAP]

Taxonomic identifier

314315 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Lactobacillales › Lactobacillaceae › Lactobacillus › Lactobacillus sakei › Lactobacillus sakei subsp. sakei

Protein attributes

Sequence length	886 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1). RuleBase RU004460
Sequence similarities	Belongs to the DNA polymerase type-A family. RuleBase RU004459 Contains 1 5'-3' exonuclease domain. SAAS SAAS002421

Ontologies

Keywords
Biological process	DNA replication RuleBase RU004460
Ligand	DNA-binding RuleBase RU004460
Molecular function	DNA-directed DNA polymerase EMBL CAI55709.1 Nucleotidyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological_process	DNA replication Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	intracellular Inferred from electronic annotation. Source: InterPro
Molecular_function	3'-5' exonuclease activity Inferred from electronic annotation. Source: InterPro 5'-3' exonuclease activity Inferred from electronic annotation. Source: InterPro DNA binding Inferred from electronic annotation. Source: UniProtKB-KW DNA-directed DNA polymerase activity Inferred from electronic annotation. Source: UniProtKB-KW
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q38VS4 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: 44CC6C8F571BEDF3	FASTA	886	99,439
	10 20 30 40 50 60 MGSQKSLLLI DGNSVAFRAF YAMHQVLDSF TNQDGLHTNA IYAFKNMLDI ILKRFEPTHV 70 80 90 100 110 120 LVAFDAGKTT FRTAQFADYK GGRSKTPPEL TEQFPYIKEL LHAYGIQTAE LANYEADDII 130 140 150 160 170 180 GTLASQAEQD GFVVNIVTGD RDLTQLTTDK TTVNITVKGV NDTEAYTPEH VQEKLGLAPS 190 200 210 220 230 240 QIVDLKGLMG DTSDNYPGVT KVGEKTALKL LTEFGSIEGV YENVDAMKKS KMKEHLIEDR 250 260 270 280 290 300 DQAFMSKKLA TILRDAPIET TLADITYEGP NIDTLIAFYQ EMNFQNFLKQ LNVTPEAVEP 310 320 330 340 350 360 AENYQYTVLT LDNLETVQAI KTPVAFGVEM LTDNYHTADL IGFYIGAPDH WYVSDDVALL 370 380 390 400 410 420 AEPVLKDWLE DASHPKAVFG VKRTQVAANR LGVHLAGVDF DLLLASYLLN TTNNSNDLGT 430 440 450 460 470 480 VANLHEYQNV QTDEAVYGKG AKRAVPTEPA LLYQHLVQKA AAIYHLQPQL EEQLKEHQQF 490 500 510 520 530 540 DLFTDMELPL ALVLAQMEIT GIRVDASRLQ QMGSEFSQTL KILEEKVYAE AGETFNINSP 550 560 570 580 590 600 KQLGVILFEK MGLPVVKKTK TGYSTAVDVL EQLRKDAPIV QTILDYRQIA KIQSTYVEGL 610 620 630 640 650 660 LKSIHQDNKV HTRYLQTLTQ TGRLSSVDPN LQNIPVRLAE GRKIRQAFVP SHPDWQMFAS 670 680 690 700 710 720 DYSQIELRVL AHISGDANMQ EAFKEDRDIH ANTAMKIFGL NSADEVTPDM RRQAKATNFG 730 740 750 760 770 780 IVYGISDYGL SQNIGISRQE AKRFIDAYFE QYPGVQQFMV DIVKKAREEG YVETLFHRRR 790 800 810 820 830 840 YLPDIHAKNF NLRSFAERTA MNTPIQGSAA DIIKVAMILM QQELKKANLQ ARMLLQVHDE 850 860 870 880 LIFEAPTEEI PILQKLVPSV MDSAVKLAVP LKVESGFGPT WYDIKK

References

[1]

"The complete genome sequence of the meat-borne lactic acid bacterium Lactobacillus sakei 23K." Chaillou S., Champomier-Verges M.-C., Cornet M., Crutz-Le Coq A.-M., Dudez A.-M., Martin V., Beaufils S., Darbon-Rongere E., Bossy R., Loux V., Zagorec M. Nat. Biotechnol. 23:1527-1533(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 23K.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR936503 Genomic DNA. Translation: CAI55709.1.
RefSeq	YP_396016.1. NC_007576.1.
3D structure databases
ProteinModelPortal	Q38VS4.
SMR	Q38VS4. Positions 322-885.
ModBase	Search...
Protein-protein interaction databases
STRING	314315.LSA1406.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	CAI55709; CAI55709; LCA_1406.
GeneID	3778057.
KEGG	lsa:LSA1406.
PATRIC	22275614. VBILacSak116432_1370.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG0258.
HOGENOM	HOG000020997.
KO	K02335.
OMA	EQRRYAK.
Family and domain databases
InterPro	IPR002562. 3'-5'_exonuclease_dom. IPR020046. 5-3_exonucl_a-hlix_arch_N. IPR020045. 5-3_exonuclease_C. IPR002421. 5-3_exonuclease_N. IPR019760. DNA-dir_DNA_pol_A_CS. IPR001098. DNA-dir_DNA_pol_A_palm_dom. IPR018320. DNA_polymerase_1. IPR002298. DNA_polymerase_A. IPR008918. HhH2. IPR012337. RNaseH-like_dom. [Graphical view]
Pfam	PF01367. 5_3_exonuc. 1 hit. PF02739. 5_3_exonuc_N. 1 hit. PF00476. DNA_pol_A. 1 hit. [Graphical view]
PRINTS	PR00868. DNAPOLI.
SMART	SM00474. 35EXOc. 1 hit. SM00475. 53EXOc. 1 hit. SM00279. HhH2. 1 hit. SM00482. POLAc. 1 hit. [Graphical view]
SUPFAM	SSF47807. 5_3_exo_C. 1 hit. SSF53098. RNaseH_fold. 1 hit.
TIGRFAMs	TIGR00593. pola. 1 hit.
PROSITE	PS00447. DNA_POLYMERASE_A. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q38VS4_LACSS

Accession

Primary (citable) accession number: Q38VS4

Entry history

Integrated into UniProtKB/TrEMBL:	November 22, 2005
Last sequence update:	November 22, 2005
Last modified:	May 1, 2013
This is version 67 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)