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Q38VQ9 (SYR_LACSS) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 56. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine--tRNA ligase

EC=6.1.1.19
Alternative name(s):
Arginyl-tRNA synthetase
Short name=ArgRS
Gene names
Name:argS
Ordered Locus Names:LCA_1421
OrganismLactobacillus sakei subsp. sakei (strain 23K) [Complete proteome] [HAMAP]
Taxonomic identifier314315 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliLactobacillalesLactobacillaceaeLactobacillus

Protein attributes

Sequence length563 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP-Rule MF_00123

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00123

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00123.

Sequence similarities

Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
   Biological processProtein biosynthesis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionAminoacyl-tRNA synthetase
Ligase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processarginyl-tRNA aminoacylation

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-HAMAP

arginine-tRNA ligase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 563563Arginine--tRNA ligase HAMAP-Rule MF_00123
PRO_0000242036

Regions

Motif122 – 13211"HIGH" region HAMAP-Rule MF_00123

Sequences

Sequence LengthMass (Da)Tools
Q38VQ9 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: B596E667A0139567

FASTA56362,972
        10         20         30         40         50         60 
MDFKQQVVTA LTGVLGDSLP AEKVAQLIET PKTSDLGDYA FPTFILAKTL RKAPQQIAQD 

        70         80         90        100        110        120 
LVDQMDVAGF EKVIANGPYI NFFLDKAAFS DQILKTVLTE AAKYGESDLG HGGNVPIDMS 

       130        140        150        160        170        180 
SPNIAKPISM GHLRSTVIGN SIAKILTKVG FNPIKINHLG DWGTQFGKLI VAYKKWGSEE 

       190        200        210        220        230        240 
EVKEDPITNL LKYYVKFHQE DVEHPELDDE ARAWFRKLEA GDEEATQLWS WFRSESLKEF 

       250        260        270        280        290        300 
QKIYDMLGVE FDSYNGEAFY NDKMDAVVEA IESKGLLQES RGAEIVDLTA YNLNPALIKK 

       310        320        330        340        350        360 
SDGATLYMTR DLAAAMYRHD TYNFVQSLYV VGGEQREHFN QLKAVLKEMG NDWSDEIHHI 

       370        380        390        400        410        420 
PFGLITQGGK KLSTRSGRVI LLEEVLNDAV KLAGAQIEAK NPDLPNREEV AKQVGIGAVI 

       430        440        450        460        470        480 
FHDLKNDRLD NFDFDLEEVV RFEGETGPYV QYTNARAQSI LRKANQEVVV DDQLVVADDN 

       490        500        510        520        530        540 
AWDVLKMLSN FPAVIARASK EYEPSIVAKY ALRLAKAFNK YYANSKILAD DDQRNARLSL 

       550        560 
VKSVSIVLET ALDLLGVQAP KEM 

« Hide

References

[1]"The complete genome sequence of the meat-borne lactic acid bacterium Lactobacillus sakei 23K."
Chaillou S., Champomier-Verges M.-C., Cornet M., Crutz-Le Coq A.-M., Dudez A.-M., Martin V., Beaufils S., Darbon-Rongere E., Bossy R., Loux V., Zagorec M.
Nat. Biotechnol. 23:1527-1533(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 23K.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR936503 Genomic DNA. Translation: CAI55724.1.
RefSeqYP_396031.1. NC_007576.1.

3D structure databases

ProteinModelPortalQ38VQ9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING314315.LSA1421.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAI55724; CAI55724; LCA_1421.
GeneID3777328.
KEGGlsa:LSA1421.
PATRIC22275646. VBILacSak116432_1386.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0018.
KOK01887.
OMAYVKFHDE.
OrthoDBEOG6JB13C.

Family and domain databases

Gene3D1.10.730.10. 1 hit.
3.30.1360.70. 1 hit.
3.40.50.620. 1 hit.
HAMAPMF_00123. Arg_tRNA_synth.
InterProIPR001278. Arg-tRNA-ligase.
IPR005148. Arg-tRNA-synth_N.
IPR008909. DALR_anticod-bd.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
[Graphical view]
PANTHERPTHR11956. PTHR11956. 1 hit.
PfamPF03485. Arg_tRNA_synt_N. 1 hit.
PF05746. DALR_1. 1 hit.
PF00750. tRNA-synt_1d. 1 hit.
[Graphical view]
PRINTSPR01038. TRNASYNTHARG.
SMARTSM01016. Arg_tRNA_synt_N. 1 hit.
SM00836. DALR_1. 1 hit.
[Graphical view]
SUPFAMSSF47323. SSF47323. 1 hit.
SSF55190. SSF55190. 1 hit.
TIGRFAMsTIGR00456. argS. 1 hit.
ProtoNetSearch...

Entry information

Entry nameSYR_LACSS
AccessionPrimary (citable) accession number: Q38VQ9
Entry history
Integrated into UniProtKB/Swiss-Prot: June 27, 2006
Last sequence update: November 22, 2005
Last modified: May 14, 2014
This is version 56 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Aminoacyl-tRNA synthetases

List of aminoacyl-tRNA synthetase entries