Q38V07 (ADEC2_LACSS) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Adenine deaminase 2
Short name=Adenase 2
Short name=Adenine aminase 2
EC=3.5.4.2

Gene names

Name:	ade2
Synonyms:	adeC2
Ordered Locus Names:	LCA_1670

Organism

Lactobacillus sakei subsp. sakei (strain 23K) [Complete proteome] [HAMAP]

Taxonomic identifier

314315 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Lactobacillales › Lactobacillaceae › Lactobacillus

Protein attributes

Sequence length	580 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Adenine + H2O = hypoxanthine + NH3. HAMAP MF_01518
Cofactor	Manganese By similarity. HAMAP MF_01518
Sequence similarities	Belongs to the adenine deaminase family.

Ontologies

Keywords
Ligand	Manganese
Molecular function	Hydrolase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	adenine catabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	adenine deaminase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 580	580	Adenine deaminase 2 HAMAP MF_01518		PRO_0000292385

Sequences

	Sequence		Length	Mass (Da)
	Q38V07 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: 62E5816D90C9E22E	FASTA	580	61,849
	10 20 30 40 50 60 MDKSTLKQLI DQAAGRKPAD TIIKNAKIVD VYNARIIEGT LAIADSRFLG IDAAYTADNV 70 80 90 100 110 120 INAHGQYVVP GLIDPHIHIE SANVSPAVFG SLVTPHGTTT ILADPHEIVN VAGMRGLEYM 130 140 150 160 170 180 VASAKNTALD IKYTMPSCVP AANPTLETSG AVITADEIKQ SYDQGLTYGL AEFMNYPGVV 190 200 210 220 230 240 NADDGVLDEL LVSLNARKMI DGHSPALHGQ GLNAYAAAGV HNDHECTQVD EMLDRISRGM 250 260 270 280 290 300 YVYLRYGTVS KNMPTLLKGV TPQNARFCCL CGDDLQSVTL RETGHLDESI RVAIQNGIDP 310 320 330 340 350 360 LTAIQMATIN TAQCTGLSDR GGIAPGLKAD FLLVDDLEHF NVNQTFIDGQ KIAANGAYLL 370 380 390 400 410 420 PTDDSVAGFD DLLETVHLDN FSADQLKLNL TSDKAHVIGL QSISRTQNLV LPVAHDAEGD 430 440 450 460 470 480 FHYKPSEDIV KVAVVERHHL TGNVGVGLLS GFGLQNGAIA TSIGHDSHNL VVVGTNDADM 490 500 510 520 530 540 VVAIDALKAC QGGGVAVQNG QVIATLPFVI GGLMSTEPID SLIAHQKAFN TICHEQLNVT 550 560 570 580 AQFDPIMKLG AMPLDVIPNL RITDKGLVDV TKFEIIDINA

References

[1]

"The complete genome sequence of the meat-borne lactic acid bacterium Lactobacillus sakei 23K." Chaillou S., Champomier-Verges M.-C., Cornet M., Crutz-Le Coq A.-M., Dudez A.-M., Martin V., Beaufils S., Darbon-Rongere E., Bossy R., Loux V., Zagorec M. Nat. Biotechnol. 23:1527-1533(2005) [PubMed: 16273110] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 23K.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR936503 Genomic DNA. Translation: CAI55977.1.
RefSeq	YP_396283.1. NC_007576.1.
3D structure databases
ProteinModelPortal	Q38V07.
ModBase	Search...
Protein-protein interaction databases
STRING	Q38V07.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	3778143.
GenomeReviews	Gene locus LCA_1670 in contig CR936503_GR.
KEGG	lsa:LSA1670.
PATRIC	22276170. VBILacSak116432_1636.
Organism-specific databases
CMR	Search...
Phylogenomic databases
eggNOG	COG1001.
HOGENOM	HBG725357.
OMA	VGLGEMM.
PhylomeDB	Q38V07.
Enzyme and pathway databases
BioCyc	LSAK314315:LSA1670-MONOMER.
Family and domain databases
HAMAP	MF_01518. Adenine_deamin. [Tree]
InterPro	IPR006679. Adenine_deam. IPR006680. Amidohydro_1. IPR011059. Metal-dep_hydrolase_composite. [Graphical view]
KO	K01486.
Pfam	PF01979. Amidohydro_1. 2 hits. [Graphical view]
SUPFAM	SSF51338. Metalo_hydrolase. 1 hit.
TIGRFAMs	TIGR01178. Ade. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ADEC2_LACSS

Accession

Primary (citable) accession number: Q38V07

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 26, 2007
Last sequence update:	November 22, 2005
Last modified:	January 25, 2012
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program