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Protein
Submitted name:

Thymidine kinase, putative

Gene

Tb10.70.7270

Organism
Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi341ZincCombined sources1
Metal bindingi344ZincCombined sources1
Metal bindingi374ZincCombined sources1
Metal bindingi377ZincCombined sources1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinaseImported, Transferase
LigandMetal-bindingCombined sources, ZincCombined sources

Names & Taxonomyi

Protein namesi
Submitted name:
Thymidine kinase, putativeImported (EC:2.7.1.21Imported)
Gene namesi
ORF Names:Tb10.70.7270Imported
OrganismiTrypanosoma brucei brucei (strain 927/4 GUTat10.1)Imported
Taxonomic identifieri185431 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosoma
Proteomesi
  • UP000008524 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiTriTrypDB:Tb927.10.880

Subcellular locationi

GO - Cellular componenti

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Disulfide bondi325InterchainCombined sources

Proteomic databases

PaxDbiQ38CF2

Interactioni

Protein-protein interaction databases

STRINGi5691.EAN77518

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
5FUVX-ray2.30A/B203-384[»]
5FUWX-ray2.20A/B203-384[»]
5FUXX-ray2.20A/B203-384[»]
5FUYX-ray2.80A/B/C/D/E/F203-384[»]
ProteinModelPortaliQ38CF2
SMRiQ38CF2
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the thymidine kinase family.UniRule annotation

Phylogenomic databases

InParanoidiQ38CF2
KOiK00857

Family and domain databases

InterProiView protein in InterPro
IPR027417 P-loop_NTPase
IPR001267 Thymidine_kinase
IPR020633 Thymidine_kinase_CS
PANTHERiPTHR11441 PTHR11441, 2 hits
PfamiView protein in Pfam
PF00265 TK, 2 hits
SUPFAMiSSF52540 SSF52540, 2 hits
PROSITEiView protein in PROSITE
PS00603 TK_CELLULAR_TYPE, 2 hits

Sequencei

Sequence statusi: Complete.

Q38CF2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHDGDGNIEL IIGPMFAGKT TELMRRVQRH KHAQRSCYII NYSRNSYQNQ
60 70 80 90 100
RLSTHDQLSL TANVSIAKLS EVCDEWRDYD VIAVDNGQFF PDVVGFCARA
110 120 130 140 150
ANEGKTVIVS ALDVDCRETP FDEVCRLVPR AESVLKLSAV CMECHEHDAF
160 170 180 190 200
LTYRTIESNE RELYGGADMY LAVCRWCYKQ LTMSHVDAQK TSASTAAVVP
210 220 230 240 250
NGAHGRIELI IGPMFAGKTT ELMRRVQRHK HAQRSCYIIK YTGDTRYSEG
260 270 280 290 300
AITSHDQRAL TANVSVSNLH DVGDEWRKYD VIAVDEGQFF PGVAAFCSKA
310 320 330 340 350
ADSGKVVIVS ALDADYLQEP FEEICLLVSR ADSVVKLSAV CMECHNRKAS
360 370 380 390 400
FTYRTVKSDE RKLVGGSDMY MSVCRSCYET KRNMVQTEKY IYSCVGINEG
410 420 430 440 450
SYSECSPGPS ERSSAGTSGV QTSVKVDEQN CTEPNTEAKK MPLKRKRNQM

AVDTT
Length:455
Mass (Da):50,844
Last modified:November 22, 2005 - v1
Checksum:i23B651D305F9BB8E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000208 Genomic DNA Translation: EAN77518.1
RefSeqiXP_822346.1, XM_817253.1

Genome annotation databases

GeneDBiTb927.10.880:pep
GeneIDi3662841
KEGGitbr:Tb10.70.7270

Similar proteinsi

Entry informationi

Entry nameiQ38CF2_TRYB2
AccessioniPrimary (citable) accession number: Q38CF2
Entry historyiIntegrated into UniProtKB/TrEMBL: November 22, 2005
Last sequence update: November 22, 2005
Last modified: April 25, 2018
This is version 71 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

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