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Protein
Submitted name:

Methionyl-tRNA synthetase, putative

Gene

Tb10.70.6470

Organism
Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei250ATP analog; via amide nitrogenCombined sources1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi259 – 262ATP analogCombined sources4
Nucleotide bindingi547 – 548ATP analogCombined sources2

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionAminoacyl-tRNA synthetaseUniRule annotationImported, Ligase
Biological processProtein biosynthesisUniRule annotation
LigandATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BRENDAi6.1.1.10 6519

Names & Taxonomyi

Protein namesi
Submitted name:
Methionyl-tRNA synthetase, putativeImported (EC:6.1.1.10Imported)
Gene namesi
ORF Names:Tb10.70.6470Imported
OrganismiTrypanosoma brucei brucei (strain 927/4 GUTat10.1)Imported
Taxonomic identifieri185431 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosoma
Proteomesi
  • UP000008524 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiTriTrypDB:Tb927.10.1500

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Chemistry databases

ChEMBLiCHEMBL2146303

PTM / Processingi

Proteomic databases

PaxDbiQ38C91

Interactioni

Protein-protein interaction databases

STRINGi5691.EAN77579

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
4EG1X-ray2.90A/B237-773[»]
4EG3X-ray2.94A/B237-773[»]
4EG4X-ray3.15A/B237-773[»]
4EG5X-ray3.10A/B237-773[»]
4EG6X-ray2.90A/B235-773[»]
4EG7X-ray2.75A/B237-773[»]
4EG8X-ray2.60A/B237-773[»]
4EGAX-ray2.70A/B237-773[»]
4MVWX-ray2.90A/B237-773[»]
4MVXX-ray2.55A/B237-773[»]
4MVYX-ray2.31A/B237-773[»]
4MW0X-ray2.20A/B237-773[»]
4MW1X-ray2.49A/B237-773[»]
4MW2X-ray2.30A/B237-773[»]
4MW4X-ray2.50A/B237-773[»]
4MW5X-ray2.35A/B237-773[»]
4MW6X-ray2.56A/B237-773[»]
4MW7X-ray2.75A/B237-773[»]
4MW9X-ray2.65A/B237-773[»]
4MWBX-ray2.31A/B237-773[»]
4MWCX-ray2.65A/B237-773[»]
4MWDX-ray2.25A/B237-773[»]
4MWEX-ray2.45A/B237-773[»]
4ZT2X-ray2.70A/B237-773[»]
4ZT3X-ray2.80A/B237-773[»]
4ZT4X-ray2.30A/B237-773[»]
4ZT5X-ray2.35A/B237-773[»]
4ZT6X-ray2.25A/B237-773[»]
4ZT7X-ray2.40A/B237-773[»]
5J58X-ray2.80A/B237-773[»]
5J59X-ray2.40A/B237-773[»]
5J5AX-ray2.70A/B237-773[»]
5NFHX-ray2.80A/B237-767[»]
5TQUX-ray2.60A/B237-773[»]
5V49X-ray2.30A/B237-773[»]
ProteinModelPortaliQ38C91
SMRiQ38C91
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini242 – 617tRNA-synt_1gInterPro annotationAdd BLAST376

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000200401
InParanoidiQ38C91
KOiK01874
OMAiTYVWFDA

Family and domain databases

CDDicd00814 MetRS_core, 1 hit
Gene3Di3.40.50.620, 2 hits
InterProiView protein in InterPro
IPR014758 Met-tRNA_synth
IPR015413 Methionyl/Leucyl_tRNA_Synth
IPR033911 MetRS_core
IPR014729 Rossmann-like_a/b/a_fold
IPR009080 tRNAsynth_Ia_anticodon-bd
PfamiView protein in Pfam
PF09334 tRNA-synt_1g, 1 hit
PRINTSiPR01041 TRNASYNTHMET
SUPFAMiSSF47323 SSF47323, 1 hit
TIGRFAMsiTIGR00398 metG, 1 hit

Sequencei

Sequence statusi: Complete.

Q38C91-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MALKLLSEKA NSQALKVLLC SYYVKRPVEV SLSGAYATPI LHHPAFKQPI
60 70 80 90 100
IAPNEMARVI LFYSVEPTSN NGGAADSSNG DGTASPVAGL TNLTLEHETW
110 120 130 140 150
LEWEATTFTR AVHPLYTQRR QTAESLAVFS YLDKKISEND DRCVYSPAVE
160 170 180 190 200
GKGAADPTDA VSTFFIDCIV WCAVLPALCE SGVLRDSEKQ QLPHLVKWFN
210 220 230 240 250
TFQKEQKTLI DNAFENLSVQ EAADFLRCPR VYKVSAKVEK VFFVTSPIYY
260 270 280 290 300
VNAAPHIGHV YSTLITDVIG RYHRVKGERV FALTGTDEHG QKVAEAAKQK
310 320 330 340 350
QVSPYDFTAA VAGEFKKCFE QMDYSIDYFI RTTNEQHKAV VKELWTKLEQ
360 370 380 390 400
KGDIYLGRYE GWYSISDESF LTPQNITDGV DKDGNPCKVS LESGHVVTWV
410 420 430 440 450
SEENYMFRLS AFRERLLEWY HANPGCIVPE FRRREVIRAV EKGLPDLSVS
460 470 480 490 500
RKKETLHNWA IPVPGNPDHC VYVWLDALTN YLTGSRLRVD ESGKEVSLAD
510 520 530 540 550
DFSELERFPA DVHVIGKDIL KFHAIYWPAF LLSAGLPLPK KIVAHGWWTK
560 570 580 590 600
DRKKISKSLG NVFDPVEKAE EFGYDALKYF LLRESGFSDD GDYSDKNMIA
610 620 630 640 650
RLNGELADTL GNLVMRCTSA KINVNGEWPS PAAYTEEDES LIQLIKDLPG
660 670 680 690 700
TADHYYLIPD IQKAIIAVFD VLRAINAYVT DMAPWKLVKT DPERLRTVLY
710 720 730 740 750
ITLEGVRVTT LLLSPILPRK SVVIFDMLGV PEVHRKGIEN FEFGAVPPGT
760 770
RLGPAVEGEV LFSKRSTENT KST
Length:773
Mass (Da):86,911
Last modified:November 22, 2005 - v1
Checksum:i8BE9FB1CFB52A1B1
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000208 Genomic DNA Translation: EAN77579.1
RefSeqiXP_822407.1, XM_817314.1

Genome annotation databases

GeneDBiTb927.10.1500:pep
GeneIDi3662741
KEGGitbr:Tb10.70.6470

Similar proteinsi

Entry informationi

Entry nameiQ38C91_TRYB2
AccessioniPrimary (citable) accession number: Q38C91
Entry historyiIntegrated into UniProtKB/TrEMBL: November 22, 2005
Last sequence update: November 22, 2005
Last modified: April 25, 2018
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

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