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Protein

Phosphotransferase

Gene

Tb10.70.5800

Organism
Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Status
Unreviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

GO - Biological processi

  • carbohydrate metabolic process Source: GeneDB
  • cellular glucose homeostasis Source: GO_Central
  • glycolytic process Source: GeneDB
Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotationImported, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Enzyme and pathway databases

SABIO-RKQ38C41.

Names & Taxonomyi

Protein namesi
Recommended name:
PhosphotransferaseUniRule annotation (EC:2.7.1.-UniRule annotation)
Gene namesi
ORF Names:Tb10.70.5800Imported
OrganismiTrypanosoma brucei brucei (strain 927/4 GUTat10.1)Imported
Taxonomic identifieri185431 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosoma
Proteomesi
  • UP000008524 Componenti: Chromosome 10

Organism-specific databases

EuPathDBiTriTrypDB:Tb927.10.2020.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: GO_Central
  • glycosome Source: GeneDB
Complete GO annotation...

Pathology & Biotechi

Chemistry

ChEMBLiCHEMBL1741201.

Interactioni

Chemistry

BindingDBiQ38C41.

Structurei

3D structure databases

ProteinModelPortaliQ38C41.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini33 – 223191Hexokinase_1InterPro annotationAdd
BLAST
Domaini231 – 465235Hexokinase_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotationSAAS annotation

Phylogenomic databases

HOGENOMiHOG000162670.
InParanoidiQ38C41.
KOiK00844.
OMAiTRRMVVE.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q38C41-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSRRLNNILE HISIQGNDGE TVRAVKRDVA MAALTNQFTM SVESMRQIMT
60 70 80 90 100
YLLYEMVEGL EGRESTVRML PSYVYKADPK RATGVFYALD LGGTNFRVLR
110 120 130 140 150
VACKEGAVVD SSTSAFKIPK YALEGNATDL FDFIASNVKK TMETRAPEDL
160 170 180 190 200
NRTVPLGFTF SFPVEQTKVN RGVLIRWTKG FSTKGVQGND VIALLQAAFG
210 220 230 240 250
RVSLKVNVVA LCNDTVATMI SHYFKDPEVQ VGVIIGTGSN ACYFETASAV
260 270 280 290 300
TKDPAVAARG SALTPISMES GNFDSKYRFV LPTTKFDLDI DDASLNKGQQ
310 320 330 340 350
ALEKMISGMY LGEIARRVIV HLSSINCLPA ALQTALGNRG SFESRFAGMI
360 370 380 390 400
SADRMPGLQF TRSTIQKVCG VDVQSIEDLR IIRDVCRLVR GRAAQLSASF
410 420 430 440 450
CCAPLVKTQT QGRATIAIDG SVFEKIPSFR RVLQDNINRI LGPECDVRAV
460 470
LAKGGSGVGA ALISAIVADG K
Length:471
Mass (Da):51,149
Last modified:November 22, 2005 - v1
Checksum:i0D8FE91694432C6F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000208 Genomic DNA. Translation: EAN77629.1.
RefSeqiXP_822457.1. XM_817364.1.

Genome annotation databases

EnsemblProtistsiEAN77629; EAN77629; Tb10.70.5800.
GeneDBiTb927.10.2020:pep.
GeneIDi3663016.
KEGGitbr:Tb10.70.5800.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CM000208 Genomic DNA. Translation: EAN77629.1.
RefSeqiXP_822457.1. XM_817364.1.

3D structure databases

ProteinModelPortaliQ38C41.
ModBaseiSearch...
MobiDBiSearch...

Chemistry

BindingDBiQ38C41.
ChEMBLiCHEMBL1741201.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAN77629; EAN77629; Tb10.70.5800.
GeneDBiTb927.10.2020:pep.
GeneIDi3663016.
KEGGitbr:Tb10.70.5800.

Organism-specific databases

EuPathDBiTriTrypDB:Tb927.10.2020.

Phylogenomic databases

HOGENOMiHOG000162670.
InParanoidiQ38C41.
KOiK00844.
OMAiTRRMVVE.

Enzyme and pathway databases

SABIO-RKQ38C41.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ38C41_TRYB2
AccessioniPrimary (citable) accession number: Q38C41
Entry historyi
Integrated into UniProtKB/TrEMBL: November 22, 2005
Last sequence update: November 22, 2005
Last modified: September 7, 2016
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.