Q38C41 (Q38C41_TRYB2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Hexokinase EMBL EAN77629.1
EC=2.7.1.1 EMBL EAN77629.1

Gene names

ORF Names:

Tb10.70.5800 EMBL EAN77629.1

Organism

Trypanosoma brucei brucei (strain 927/4 GUTat10.1) [Reference proteome]

Taxonomic identifier

999953 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Trypanosoma › Trypanozoon › Trypanosoma brucei › Trypanosoma brucei brucei

Protein attributes

Sequence length	471 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Sequence similarities

Belongs to the hexokinase family. RuleBase RU004510

Ontologies

Keywords
Biological process	Glycolysis RuleBase RU004049 SAAS SAAS001312
Ligand	ATP-binding RuleBase RU004049 SAAS SAAS001312 Nucleotide-binding
Molecular function	Kinase RuleBase RU004049 SAAS SAAS001312 EMBL EAN77629.1 Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	glycolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW hexokinase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q38C41 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: 0D8FE91694432C6F	FASTA	471	51,149
	10 20 30 40 50 60 MSRRLNNILE HISIQGNDGE TVRAVKRDVA MAALTNQFTM SVESMRQIMT YLLYEMVEGL 70 80 90 100 110 120 EGRESTVRML PSYVYKADPK RATGVFYALD LGGTNFRVLR VACKEGAVVD SSTSAFKIPK 130 140 150 160 170 180 YALEGNATDL FDFIASNVKK TMETRAPEDL NRTVPLGFTF SFPVEQTKVN RGVLIRWTKG 190 200 210 220 230 240 FSTKGVQGND VIALLQAAFG RVSLKVNVVA LCNDTVATMI SHYFKDPEVQ VGVIIGTGSN 250 260 270 280 290 300 ACYFETASAV TKDPAVAARG SALTPISMES GNFDSKYRFV LPTTKFDLDI DDASLNKGQQ 310 320 330 340 350 360 ALEKMISGMY LGEIARRVIV HLSSINCLPA ALQTALGNRG SFESRFAGMI SADRMPGLQF 370 380 390 400 410 420 TRSTIQKVCG VDVQSIEDLR IIRDVCRLVR GRAAQLSASF CCAPLVKTQT QGRATIAIDG 430 440 450 460 470 SVFEKIPSFR RVLQDNINRI LGPECDVRAV LAKGGSGVGA ALISAIVADG K

References

[1]

"The genome of the African trypanosome Trypanosoma brucei." Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U., Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B., Alsmark U.C.M. , Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F., Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C., Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A., Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D., Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D., Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S., Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S., Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G., Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A., Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M., Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S., Walker D., Wanless D., Wang S., White B., White O., Whitehead S., Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E., Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E., Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.A. Science 309:416-422(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 927/4 GUTat10.1 EMBL EAN77629.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CM000208 Genomic DNA. Translation: EAN77629.1.
RefSeq	XP_822457.1. XM_817364.1.
3D structure databases
ProteinModelPortal	Q38C41.
ModBase	Search...
Protein-protein interaction databases
STRING	5691.Tb10.70.5800.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	EAN77629; EAN77629; Tb10.70.5800.
GeneID	3663016.
KEGG	tbr:Tb10.70.5800.
Phylogenomic databases
eggNOG	COG5026.
HOGENOM	HOG000162670.
KO	K00844.
OMA	CLPITEY.
ProtClustDB	PTZ00107.
Enzyme and pathway databases
SABIO-RK	Q38C41.
Family and domain databases
InterPro	IPR001312. Hexokinase. IPR022673. Hexokinase_C. IPR019807. Hexokinase_CS. IPR022672. Hexokinase_N. [Graphical view]
PANTHER	PTHR19443. PTHR19443. 1 hit.
Pfam	PF00349. Hexokinase_1. 1 hit. PF03727. Hexokinase_2. 1 hit. [Graphical view]
PRINTS	PR00475. HEXOKINASE.
PROSITE	PS00378. HEXOKINASES. 1 hit. [Graphical view]
ProtoNet	Search...
Other
ChEMBL	CHEMBL1741201.

Entry information

Entry name

Q38C41_TRYB2

Accession

Primary (citable) accession number: Q38C41

Entry history

Integrated into UniProtKB/TrEMBL:	November 22, 2005
Last sequence update:	November 22, 2005
Last modified:	May 29, 2013
This is version 45 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)