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Q38AT7 (Q38AT7_TRYB2) Unreviewed, UniProtKB/TrEMBL

Last modified April 16, 2014. Version 50. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein names
EC=3.1.3.48 EMBL EAN78083.1
Gene names
ORF Names:Tb10.70.0070 EMBL EAN78083.1
OrganismTrypanosoma brucei brucei (strain 927/4 GUTat10.1) [Reference proteome]
Taxonomic identifier999953 [NCBI]
Taxonomic lineageEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosoma

Protein attributes

Sequence length306 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Catalytic activity

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate. SAAS SAAS000387

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Regions

Region230 – 2367Phosphate binding PDB 3M4U

Sequences

Sequence LengthMass (Da)Tools
Q38AT7 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: 8DF52B597AF6FC07

FASTA30634,132
        10         20         30         40         50         60 
MSTAKSFPMA QLSTRAQYSR MQREFVQLQR QENPRNINFT TSLKNRHKNR YLDILANEET 

        70         80         90        100        110        120 
IYPPVLKAVG AQPGRYPYIN GNLIDLDLPH TFVACQAPVP QGVPDFLETL SEKKVDLVVM 

       130        140        150        160        170        180 
LTKLREGGVL KAERYWPEEE EDSLSFPESG HDAIKVTRDA EASYEVDAEL DIVRRPLVIH 

       190        200        210        220        230        240 
VPGKPMHRVL QVQYVGWPDH GVPESAASFD ELLSVIKNCV TTSPILVHCS AGIGRTGTLI 

       250        260        270        280        290        300 
GAYAALLHIE RGILTDSTVY SIVAAMKQKR FGMVQRLEQY AVIYMTVLGR LGVDISGLVS 


TLNLKA 

« Hide

References

« Hide 'large scale' references
[1]"The genome of the African trypanosome Trypanosoma brucei."
Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U., Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B., Alsmark U.C.M. expand/collapse author list , Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F., Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C., Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A., Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D., Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D., Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S., Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S., Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G., Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A., Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M., Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S., Walker D., Wanless D., Wang S., White B., White O., Whitehead S., Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E., Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E., Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.A.
Science 309:416-422(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 927/4 GUTat10.1 EMBL EAN78083.1.
[2]"The Trypanosoma brucei life cycle switch TbPTP1 is structurally conserved and dephosphorylates the nucleolar protein NOPP44/46."
Chou S., Jensen B.C., Parsons M., Alber T., Grundner C.
J. Biol. Chem. 285:22075-22081(2010) [PubMed] [Europe PMC] [Abstract]
Cited for: X-RAY CRYSTALLOGRAPHY (2.39 ANGSTROMS) IN COMPLEX WITH PHOSPHATE.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CM000208 Genomic DNA. Translation: EAN78083.1.
RefSeqXP_822911.1. XM_817818.1.

3D structure databases

PDBe
RCSB PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3M4UX-ray2.39A/B1-306[»]
ProteinModelPortalQ38AT7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5691.Tb10.70.0070.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsEAN78083; EAN78083; Tb10.70.0070.
GeneID3662266.
KEGGtbr:Tb10.70.0070.

Phylogenomic databases

eggNOGCOG5599.
KOK01104.
OMAQRIGMVQ.
ProtClustDBCLSZ2443078.

Family and domain databases

InterProIPR000387. Tyr/Dual-sp_Pase.
IPR016130. Tyr_Pase_AS.
IPR000242. Tyr_Pase_rcpt/non-rcpt.
[Graphical view]
PfamPF00102. Y_phosphatase. 1 hit.
[Graphical view]
PRINTSPR00700. PRTYPHPHTASE.
SMARTSM00194. PTPc. 1 hit.
[Graphical view]
PROSITEPS00383. TYR_PHOSPHATASE_1. 1 hit.
PS50056. TYR_PHOSPHATASE_2. 1 hit.
PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ38AT7.

Entry information

Entry nameQ38AT7_TRYB2
AccessionPrimary (citable) accession number: Q38AT7
Entry history
Integrated into UniProtKB/TrEMBL: November 22, 2005
Last sequence update: November 22, 2005
Last modified: April 16, 2014
This is version 50 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)