Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Basket 0
(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Q38AT7

- Q38AT7_TRYB2

UniProt

Q38AT7 - Q38AT7_TRYB2

Protein
Submitted name:

Tyrosine specific protein phosphatase, putative

Gene

Tb10.70.0070

Organism
Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
    • BLAST
    • Align
    • Format
    • Add to basket
    • History
      Entry version 53 (01 Oct 2014)
      Sequence version 1 (22 Nov 2005)
      Previous versions | rss
    • Help video
    • Feedback
    • Comment

    Functioni

    Catalytic activityi

    Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.SAAS annotation

    GO - Molecular functioni

    1. protein tyrosine phosphatase activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Hydrolase, Protein phosphataseSAAS annotation

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Tyrosine specific protein phosphatase, putativeImported (EC:3.1.3.48Imported)
    Gene namesi
    ORF Names:Tb10.70.0070Imported
    OrganismiTrypanosoma brucei brucei (strain 927/4 GUTat10.1)Imported
    Taxonomic identifieri999953 [NCBI]
    Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosoma
    ProteomesiUP000008524: Chromosome 10

    Interactioni

    Protein-protein interaction databases

    STRINGi5691.Tb10.70.0070.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3M4UX-ray2.39A/B1-306[»]
    ProteinModelPortaliQ38AT7.
    ModBaseiSearch...
    MobiDBiSearch...

    Miscellaneous databases

    EvolutionaryTraceiQ38AT7.

    Family & Domainsi

    Region

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Regioni230 – 2367Phosphate bindingImported

    Phylogenomic databases

    eggNOGiCOG5599.
    KOiK01104.
    OMAiCTDNVIS.

    Family and domain databases

    Gene3Di3.90.190.10. 1 hit.
    InterProiIPR029021. Prot-tyrosine_phosphatase-like.
    IPR000387. Tyr/Dual-sp_Pase.
    IPR016130. Tyr_Pase_AS.
    IPR000242. Tyr_Pase_rcpt/non-rcpt.
    [Graphical view]
    PfamiPF00102. Y_phosphatase. 1 hit.
    [Graphical view]
    PRINTSiPR00700. PRTYPHPHTASE.
    SMARTiSM00194. PTPc. 1 hit.
    [Graphical view]
    SUPFAMiSSF52799. SSF52799. 1 hit.
    PROSITEiPS00383. TYR_PHOSPHATASE_1. 1 hit.
    PS50056. TYR_PHOSPHATASE_2. 1 hit.
    PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q38AT7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MSTAKSFPMA QLSTRAQYSR MQREFVQLQR QENPRNINFT TSLKNRHKNR    50
    YLDILANEET IYPPVLKAVG AQPGRYPYIN GNLIDLDLPH TFVACQAPVP 100
    QGVPDFLETL SEKKVDLVVM LTKLREGGVL KAERYWPEEE EDSLSFPESG 150
    HDAIKVTRDA EASYEVDAEL DIVRRPLVIH VPGKPMHRVL QVQYVGWPDH 200
    GVPESAASFD ELLSVIKNCV TTSPILVHCS AGIGRTGTLI GAYAALLHIE 250
    RGILTDSTVY SIVAAMKQKR FGMVQRLEQY AVIYMTVLGR LGVDISGLVS 300
    TLNLKA 306
    Length:306
    Mass (Da):34,132
    Last modified:November 22, 2005 - v1
    Checksum:i8DF52B597AF6FC07
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM000208 Genomic DNA. Translation: EAN78083.1.
    RefSeqiXP_822911.1. XM_817818.1.

    Genome annotation databases

    EnsemblProtistsiEAN78083; EAN78083; Tb10.70.0070.
    GeneIDi3662266.
    KEGGitbr:Tb10.70.0070.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CM000208 Genomic DNA. Translation: EAN78083.1 .
    RefSeqi XP_822911.1. XM_817818.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3M4U X-ray 2.39 A/B 1-306 [» ]
    ProteinModelPortali Q38AT7.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5691.Tb10.70.0070.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi EAN78083 ; EAN78083 ; Tb10.70.0070 .
    GeneIDi 3662266.
    KEGGi tbr:Tb10.70.0070.

    Phylogenomic databases

    eggNOGi COG5599.
    KOi K01104.
    OMAi CTDNVIS.

    Miscellaneous databases

    EvolutionaryTracei Q38AT7.

    Family and domain databases

    Gene3Di 3.90.190.10. 1 hit.
    InterProi IPR029021. Prot-tyrosine_phosphatase-like.
    IPR000387. Tyr/Dual-sp_Pase.
    IPR016130. Tyr_Pase_AS.
    IPR000242. Tyr_Pase_rcpt/non-rcpt.
    [Graphical view ]
    Pfami PF00102. Y_phosphatase. 1 hit.
    [Graphical view ]
    PRINTSi PR00700. PRTYPHPHTASE.
    SMARTi SM00194. PTPc. 1 hit.
    [Graphical view ]
    SUPFAMi SSF52799. SSF52799. 1 hit.
    PROSITEi PS00383. TYR_PHOSPHATASE_1. 1 hit.
    PS50056. TYR_PHOSPHATASE_2. 1 hit.
    PS50055. TYR_PHOSPHATASE_PTP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome of the African trypanosome Trypanosoma brucei."
      Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U., Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B., Alsmark U.C.M.
      , Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F., Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C., Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A., Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D., Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D., Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S., Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S., Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G., Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A., Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M., Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S., Walker D., Wanless D., Wang S., White B., White O., Whitehead S., Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E., Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E., Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.A.
      Science 309:416-422(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 927/4 GUTat10.1Imported.
    2. "The Trypanosoma brucei life cycle switch TbPTP1 is structurally conserved and dephosphorylates the nucleolar protein NOPP44/46."
      Chou S., Jensen B.C., Parsons M., Alber T., Grundner C.
      J. Biol. Chem. 285:22075-22081(2010) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (2.39 ANGSTROMS).

    Entry informationi

    Entry nameiQ38AT7_TRYB2
    AccessioniPrimary (citable) accession number: Q38AT7
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 22, 2005
    Last sequence update: November 22, 2005
    Last modified: October 1, 2014
    This is version 53 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3