ID   Q389K1_TRYB2            Unreviewed;       192 AA.
AC   Q389K1;
DT   22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2005, sequence version 1.
DT   27-MAR-2024, entry version 102.
DE   SubName: Full=60S ribosomal protein L6, putative {ECO:0000313|EMBL:EAN78519.1};
GN   ORFNames=Tb10.26.0560 {ECO:0000313|EMBL:EAN78519.1};
OS   Trypanosoma brucei brucei (strain 927/4 GUTat10.1).
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX   NCBI_TaxID=185431 {ECO:0000313|EMBL:EAN78519.1, ECO:0000313|Proteomes:UP000008524};
RN   [1] {ECO:0000313|EMBL:EAN78519.1, ECO:0000313|Proteomes:UP000008524}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:EAN78519.1,
RC   ECO:0000313|Proteomes:UP000008524};
RX   PubMed=16020726; DOI=10.1126/science.1112642;
RA   Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H.,
RA   Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U.,
RA   Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B.,
RA   Alsmark U.C., Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F.,
RA   Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C.,
RA   Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A.,
RA   Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D.,
RA   Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D.,
RA   Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S.,
RA   Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S.,
RA   Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G.,
RA   Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A.,
RA   Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M.,
RA   Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S.,
RA   Walker D., Wanless D., Wang S., White B., White O., Whitehead S.,
RA   Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E.,
RA   Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E.,
RA   Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.;
RT   "The genome of the African trypanosome Trypanosoma brucei.";
RL   Science 309:416-422(2005).
RN   [2] {ECO:0007829|PDB:4V8M}
RP   STRUCTURE BY ELECTRON MICROSCOPY (5.57 ANGSTROMS).
RX   PubMed=23395961; DOI=10.1038/nature11872;
RA   Hashem Y., des Georges A., Fu J., Buss S.N., Jossinet F., Jobe A.,
RA   Zhang Q., Liao H.Y., Grassucci R.A., Bajaj C., Westhof E.,
RA   Madison-Antenucci S., Frank J.;
RT   "High-resolution cryo-electron microscopy structure of the Trypanosoma
RT   brucei ribosome.";
RL   Nature 494:385-389(2013).
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL6 family.
CC       {ECO:0000256|ARBA:ARBA00010592}.
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DR   EMBL; CM000208; EAN78519.1; -; Genomic_DNA.
DR   RefSeq; XP_823347.1; XM_818254.1.
DR   PDB; 4V8M; EM; 5.57 A; Bv=1-192.
DR   PDBsum; 4V8M; -.
DR   AlphaFoldDB; Q389K1; -.
DR   EMDB; EMD-17208; -.
DR   EMDB; EMD-17212; -.
DR   IntAct; Q389K1; 1.
DR   STRING; 185431.Q389K1; -.
DR   SwissPalm; Q389K1; -.
DR   PaxDb; 5691-EAN78519; -.
DR   GeneID; 3661624; -.
DR   KEGG; tbr:Tb10.26.0560; -.
DR   VEuPathDB; TriTrypDB:Tb927.10.11390; -.
DR   eggNOG; KOG1694; Eukaryota.
DR   InParanoid; Q389K1; -.
DR   OMA; RPHEMIF; -.
DR   OrthoDB; 5483341at2759; -.
DR   Proteomes; UP000008524; Chromosome 10.
DR   GO; GO:0005737; C:cytoplasm; IDA:GeneDB.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0000315; C:organellar large ribosomal subunit; ISM:GeneDB.
DR   GO; GO:0042301; F:phosphate ion binding; IDA:GeneDB.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISM:GeneDB.
DR   GO; GO:0002181; P:cytoplasmic translation; IBA:GO_Central.
DR   GO; GO:0006412; P:translation; ISM:GeneDB.
DR   CDD; cd13156; KOW_RPL6; 1.
DR   Gene3D; 2.30.30.30; -; 1.
DR   InterPro; IPR000915; 60S_ribosomal_eL6.
DR   InterPro; IPR014722; Rib_uL2_dom2.
DR   InterPro; IPR041997; Ribosomal_eL6_KOW.
DR   InterPro; IPR008991; Translation_prot_SH3-like_sf.
DR   PANTHER; PTHR10715; 60S RIBOSOMAL PROTEIN L6; 1.
DR   PANTHER; PTHR10715:SF0; 60S RIBOSOMAL PROTEIN L6; 1.
DR   Pfam; PF01159; Ribosomal_L6e; 1.
DR   SUPFAM; SSF50104; Translation proteins SH3-like domain; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:4V8M};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008524};
KW   Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274};
KW   Ribosomal protein {ECO:0000256|ARBA:ARBA00022980,
KW   ECO:0000313|EMBL:EAN78519.1}.
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          109..146
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        7..25
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        109..135
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   192 AA;  21185 MW;  41992219B4B00771 CRC64;
     MPAATKKAVE KKAKKVSRKS PEYSTVRKSC KPGTIAIILA GRFRGRRAVI LKQLPKNGPL
     VISGPMKYSG VPIRRIDSRY IIATSTRVDL TGVDTSAITP EIFKREKKEK RVKSEGEFMG
     DKDKKKAESK AKKTSKAAPK GTVSDERAQL QNAIDTALIQ AIKKDPLGKE MAGYLHSVFT
     IKPGDAPHRL KW
//