true
2010-10-05
2024-01-24
104
LIPA_TRYB2
The genome of the African trypanosome Trypanosoma brucei.
Berriman M.
Ghedin E.
Hertz-Fowler C.
Blandin G.
Renauld H.
Bartholomeu D.C.
Lennard N.J.
Caler E.
Hamlin N.E.
Haas B.
Bohme U.
Hannick L.
Aslett M.A.
Shallom J.
Marcello L.
Hou L.
Wickstead B.
Alsmark U.C.M.
Arrowsmith C.
Atkin R.J.
Barron A.J.
Bringaud F.
Brooks K.
Carrington M.
Cherevach I.
Chillingworth T.J.
Churcher C.
Clark L.N.
Corton C.H.
Cronin A.
Davies R.M.
Doggett J.
Djikeng A.
Feldblyum T.
Field M.C.
Fraser A.
Goodhead I.
Hance Z.
Harper D.
Harris B.R.
Hauser H.
Hostetler J.
Ivens A.
Jagels K.
Johnson D.
Johnson J.
Jones K.
Kerhornou A.X.
Koo H.
Larke N.
Landfear S.
Larkin C.
Leech V.
Line A.
Lord A.
Macleod A.
Mooney P.J.
Moule S.
Martin D.M.
Morgan G.W.
Mungall K.
Norbertczak H.
Ormond D.
Pai G.
Peacock C.S.
Peterson J.
Quail M.A.
Rabbinowitsch E.
Rajandream M.A.
Reitter C.
Salzberg S.L.
Sanders M.
Schobel S.
Sharp S.
Simmonds M.
Simpson A.J.
Tallon L.
Turner C.M.
Tait A.
Tivey A.R.
Van Aken S.
Walker D.
Wanless D.
Wang S.
White B.
White O.
Whitehead S.
Woodward J.
Wortman J.
Adams M.D.
Embley T.M.
Gull K.
Ullu E.
Barry J.D.
Fairlamb A.H.
Opperdoes F.
Barrell B.G.
Donelson J.E.
Hall N.
Fraser C.M.
Melville S.E.
El-Sayed N.M.A.
doi:10.1126/science.1112642
2005
Science
309
416-422
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]
927/4 GUTat10.1
Eukaryota
Radical_SAM
Aldolase class I
Lipoyl_synth
Aldolase_TIM
Elp3/MiaA/NifB-like_rSAM
LIAS_N
Lipoyl_synth
rSAM
lipA
LIPOYL SYNTHASE
LIPOYL SYNTHASE, MITOCHONDRIAL
LIAS_N
Radical_SAM
lipoyl_synthase
lipoyl_synthase_like
Elp3
Radical SAM enzymes
RADICAL_SAM
Lipoyl synthase, mitochondrial
2.8.1.8
Lipoate synthase
LS
Lip-syn
Lipoic acid synthase
Tb10.61.1530
Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.
This protein may be expected to contain an N-terminal transit peptide but none has been predicted.
Belongs to the radical SAM superfamily. Lipoyl synthase family.
Lipoyl synthase, mitochondrial
45476
1
409
Radical SAM core
142
364
Disordered
21
41
125
130
136
159
163
166
375
1
2
4Fe-4S-S-AdoMet
2005-11-22
1
45476
dcbddeb4b9baa55a3214d61cc13d3466
MFQRWSFALCRPIVAAAQVSQQQVPPSEEPRNESGAANPPLVKEEFLRQFRERLANDKTGRNSLEGFLDLPENLPPTAASIGPLKRGKEPLPPWLKLKVPMGASRQPRFNKIRRNMREKRLATVCEEAKCPNIGECWGGGDEEGDGTATATIMVMGAHCTRGCRFCSVMTSRTPPPLDPEEPRKTADAVADMGVEYIVMTMVDRDDLADGGAAHVVRCVTAVKERNPGLLLEALVGDFHGDLKLVEMVAGSPLNVYAHNIECVERITPNVRDRRASYRQSLKVLEHVNNFTKGAMLTKSSIMLGLGEKEEEVRQTLRDLRTAGVSAVTLGQYLQPSRTRLKVSRYAHPKEFEMWEKEALDMGFLYCASGPMVRSSYRAGEYYIKNILKQRETVEAPSVSDGGNEPKDSE
true
true
true
true
true
true