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Protein

Expansin-A6

Gene

EXPA6

Organism
Arabidopsis thaliana (Mouse-ear cress)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Experimental evidence at transcript leveli

Functioni

Causes loosening and extension of plant cell walls by disrupting non-covalent bonding between cellulose microfibrils and matrix glucans. No enzymatic activity has been found (By similarity).By similarity

GO - Biological processi

  • plant-type cell wall organization Source: InterPro
  • syncytium formation Source: TAIR
Complete GO annotation...

Keywords - Biological processi

Cell wall biogenesis/degradation

Names & Taxonomyi

Protein namesi
Recommended name:
Expansin-A6
Short name:
AtEXPA6
Alternative name(s):
Alpha-expansin-6
Short name:
At-EXP6
Short name:
AtEx6
Ath-ExpAlpha-1.8
Gene namesi
Name:EXPA6
Synonyms:EXP6
Ordered Locus Names:At2g28950
ORF Names:T9I4.3
OrganismiArabidopsis thaliana (Mouse-ear cress)
Taxonomic identifieri3702 [NCBI]
Taxonomic lineageiEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaerosidsmalvidsBrassicalesBrassicaceaeCamelineaeArabidopsis
Proteomesi
  • UP000006548 Componenti: Chromosome 2

Organism-specific databases

TAIRiAT2G28950.

Subcellular locationi

GO - Cellular componenti

  • extracellular region Source: UniProtKB-KW
  • membrane Source: UniProtKB-SubCell
  • plant-type cell wall Source: TAIR
Complete GO annotation...

Keywords - Cellular componenti

Cell wall, Membrane, Secreted

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2020Sequence analysisAdd
BLAST
Chaini21 – 257237Expansin-A6PRO_0000008687Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Disulfide bondi52 ↔ 80PROSITE-ProRule annotation
Disulfide bondi83 ↔ 158PROSITE-ProRule annotation
Disulfide bondi88 ↔ 95PROSITE-ProRule annotation

Keywords - PTMi

Disulfide bond

Proteomic databases

PaxDbiQ38865.
PRIDEiQ38865.

Expressioni

Gene expression databases

GenevisibleiQ38865. AT.

Interactioni

Protein-protein interaction databases

STRINGi3702.AT2G28950.1.

Structurei

3D structure databases

ProteinModelPortaliQ38865.
SMRiQ38865. Positions 26-245.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini49 – 163115Expansin-like EG45PROSITE-ProRule annotationAdd
BLAST
Domaini173 – 25280Expansin-like CBDPROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the expansin family. Expansin A subfamily.Curated
Contains 1 expansin-like CBD domain.PROSITE-ProRule annotation
Contains 1 expansin-like EG45 domain.PROSITE-ProRule annotation

Keywords - Domaini

Signal

Phylogenomic databases

eggNOGiENOG410IKDM. Eukaryota.
ENOG410YEM2. LUCA.
HOGENOMiHOG000220793.
InParanoidiQ38865.
OMAiNWISMSR.
PhylomeDBiQ38865.

Family and domain databases

Gene3Di2.40.40.10. 1 hit.
2.60.40.760. 1 hit.
InterProiIPR007118. Expan_Lol_pI.
IPR002963. Expansin.
IPR007112. Expansin/allergen_DPBB_dom.
IPR007117. Expansin_CBD.
IPR009009. RlpA-like_DPBB.
[Graphical view]
PfamiPF03330. DPBB_1. 1 hit.
PF01357. Pollen_allerg_1. 1 hit.
[Graphical view]
PRINTSiPR01226. EXPANSIN.
PR01225. EXPANSNFAMLY.
SMARTiSM00837. DPBB_1. 1 hit.
[Graphical view]
SUPFAMiSSF49590. SSF49590. 1 hit.
SSF50685. SSF50685. 1 hit.
PROSITEiPS50843. EXPANSIN_CBD. 1 hit.
PS50842. EXPANSIN_EG45. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q38865-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAMLGLVLSV LTTILALSEA RIPGVYNGGG WETAHATFYG GSDASGTMGG
60 70 80 90 100
ACGYGNLYSQ GYGVNTAALS TALFNNGFSC GACFELKCAS DPKWCHSGSP
110 120 130 140 150
SIFITATNFC PPNFAQPSDN GGWCNPPRPH FDLAMPMFLK IAEYRAGIVP
160 170 180 190 200
VSFRRVPCRK RGGIRFTING FRYFNLVLVT NVAGAGNIVR LGVKGTHTSW
210 220 230 240 250
MTMSRNWGQN WQSNSVLVGQ SLSFRVTSSD RRSSTSWNIA PANWKFGQTF

MGKNFRV
Length:257
Mass (Da):27,818
Last modified:March 1, 2004 - v2
Checksum:iF24152B9BF05A510
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U30480 mRNA. Translation: AAB38072.2.
AC005315 Genomic DNA. Translation: AAC33223.1.
AC005727 Genomic DNA. Translation: AAM15074.1.
CP002685 Genomic DNA. Translation: AEC08194.1.
AY058193 mRNA. Translation: AAL25606.1.
AY072409 mRNA. Translation: AAL62401.1.
AY085770 mRNA. Translation: AAM62987.1.
BT003405 mRNA. Translation: AAO30068.1.
PIRiT02727.
T50653.
RefSeqiNP_180461.1. NM_128454.2.
UniGeneiAt.23765.

Genome annotation databases

EnsemblPlantsiAT2G28950.1; AT2G28950.1; AT2G28950.
GeneIDi817444.
GrameneiAT2G28950.1; AT2G28950.1; AT2G28950.
KEGGiath:AT2G28950.

Cross-referencesi

Web resourcesi

EXPANSIN homepage

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U30480 mRNA. Translation: AAB38072.2.
AC005315 Genomic DNA. Translation: AAC33223.1.
AC005727 Genomic DNA. Translation: AAM15074.1.
CP002685 Genomic DNA. Translation: AEC08194.1.
AY058193 mRNA. Translation: AAL25606.1.
AY072409 mRNA. Translation: AAL62401.1.
AY085770 mRNA. Translation: AAM62987.1.
BT003405 mRNA. Translation: AAO30068.1.
PIRiT02727.
T50653.
RefSeqiNP_180461.1. NM_128454.2.
UniGeneiAt.23765.

3D structure databases

ProteinModelPortaliQ38865.
SMRiQ38865. Positions 26-245.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi3702.AT2G28950.1.

Proteomic databases

PaxDbiQ38865.
PRIDEiQ38865.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblPlantsiAT2G28950.1; AT2G28950.1; AT2G28950.
GeneIDi817444.
GrameneiAT2G28950.1; AT2G28950.1; AT2G28950.
KEGGiath:AT2G28950.

Organism-specific databases

TAIRiAT2G28950.

Phylogenomic databases

eggNOGiENOG410IKDM. Eukaryota.
ENOG410YEM2. LUCA.
HOGENOMiHOG000220793.
InParanoidiQ38865.
OMAiNWISMSR.
PhylomeDBiQ38865.

Miscellaneous databases

PROiQ38865.

Gene expression databases

GenevisibleiQ38865. AT.

Family and domain databases

Gene3Di2.40.40.10. 1 hit.
2.60.40.760. 1 hit.
InterProiIPR007118. Expan_Lol_pI.
IPR002963. Expansin.
IPR007112. Expansin/allergen_DPBB_dom.
IPR007117. Expansin_CBD.
IPR009009. RlpA-like_DPBB.
[Graphical view]
PfamiPF03330. DPBB_1. 1 hit.
PF01357. Pollen_allerg_1. 1 hit.
[Graphical view]
PRINTSiPR01226. EXPANSIN.
PR01225. EXPANSNFAMLY.
SMARTiSM00837. DPBB_1. 1 hit.
[Graphical view]
SUPFAMiSSF49590. SSF49590. 1 hit.
SSF50685. SSF50685. 1 hit.
PROSITEiPS50843. EXPANSIN_CBD. 1 hit.
PS50842. EXPANSIN_EG45. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Molecular cloning and sequence analysis of expansins - a highly conserved, multigene family of proteins that mediate cell wall extension in plants."
    Shcherban T.Y., Shi J., Durachko D.M., Guiltinan M.J., McQueen-Mason S.J., Shieh M., Cosgrove D.J.
    Proc. Natl. Acad. Sci. U.S.A. 92:9245-9249(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [MRNA].
    Strain: cv. Columbia.
  2. Cosgrove D.J.
    Submitted (DEC-2001) to the EMBL/GenBank/DDBJ databases
    Cited for: SEQUENCE REVISION TO 10-11.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: cv. Columbia.
  4. The Arabidopsis Information Resource (TAIR)
    Submitted (APR-2011) to the EMBL/GenBank/DDBJ databases
    Cited for: GENOME REANNOTATION.
    Strain: cv. Columbia.
  5. "Empirical analysis of transcriptional activity in the Arabidopsis genome."
    Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G.
    , Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.
    Science 302:842-846(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
    Strain: cv. Columbia.
  6. Cited for: NOMENCLATURE.

Entry informationi

Entry nameiEXPA6_ARATH
AccessioniPrimary (citable) accession number: Q38865
Secondary accession number(s): O81065, Q8LDV8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 5, 2002
Last sequence update: March 1, 2004
Last modified: February 17, 2016
This is version 121 of the entry and version 2 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Arabidopsis thaliana
    Arabidopsis thaliana: entries and gene names
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.