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Q38775 (CDC2D_ANTMA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cell division control protein 2 homolog D

EC=2.7.11.22
EC=2.7.11.23
Gene names
Name:CDC2D
OrganismAntirrhinum majus (Garden snapdragon)
Taxonomic identifier4151 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsLamialesPlantaginaceaeAntirrhineaeAntirrhinum

Protein attributes

Sequence length312 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Plays a key role in the control of the eukaryotic cell cycle.

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.

Developmental stage

Expression specific to the G2 and M phases.

Sequence similarities

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 312312Cell division control protein 2 homolog D
PRO_0000085748

Regions

Domain14 – 304291Protein kinase
Nucleotide binding20 – 289ATP By similarity

Sites

Active site1451Proton acceptor By similarity
Binding site431ATP By similarity

Amino acid modifications

Modified residue241Phosphothreonine By similarity
Modified residue251Phosphotyrosine By similarity
Modified residue1791Phosphothreonine; by CAK By similarity

Sequences

Sequence LengthMass (Da)Tools
Q38775 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: A38D2177EBF70210

FASTA31235,503
        10         20         30         40         50         60 
MAEEKSKSSA MDAFVKLEKV GEGTYGKVYR AMEKSTGKIV ALKKTRLHED EEGVPPTTLR 

        70         80         90        100        110        120 
EVSLLRMLSR DPHVVRLLDV KQGQNKEGKT VLYLVFEYMD TDLKKYIRSF KQTGESIAPM 

       130        140        150        160        170        180 
NVKSLMYQLC KGVAFCHGHG VLHRDLKPHN LLMDRKTMML KIADLGLARA YTLPIKKYTH 

       190        200        210        220        230        240 
EILTLWYRAP EVLLGATHYS PAVDMWSVAC IFAELVTQKA LFPGDSELQQ LLHIFRLLGT 

       250        260        270        280        290        300 
PNEEIWPGVS TLVDWHEYPQ WTAQPISSAV PGLDEKGLNL LSEMLHYEPS RRISAKKAME 

       310 
HPYFDELDKS GL 

« Hide

References

[1]"Distinct classes of cdc2-related genes are differentially expressed during the cell division cycle in plants."
Fobert P.R., Gaudin V., Lunness P., Coen E.S., Doonan J.H.
Plant Cell 8:1465-1476(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Flower.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X97640 mRNA. Translation: CAA66236.1.
PIRT17118.

3D structure databases

ProteinModelPortalQ38775.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

BRENDA2.7.11.22. 376.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCDC2D_ANTMA
AccessionPrimary (citable) accession number: Q38775
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: November 1, 1996
Last modified: February 19, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families