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Q38774 (CDC2C_ANTMA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 78. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cell division control protein 2 homolog C

EC=2.7.11.22
EC=2.7.11.23
Gene names
Name:CDC2C
OrganismAntirrhinum majus (Garden snapdragon)
Taxonomic identifier4151 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsLamialesPlantaginaceaeAntirrhineaeAntirrhinum

Protein attributes

Sequence length305 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Plays a key role in the control of the eukaryotic cell cycle.

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.

Developmental stage

CDC2C transcripts accumulate during S phase as well as during the G2 and M transition.

Sequence similarities

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 305305Cell division control protein 2 homolog C
PRO_0000085747

Regions

Domain4 – 297294Protein kinase
Nucleotide binding10 – 189ATP By similarity

Sites

Active site1381Proton acceptor By similarity
Binding site331ATP By similarity

Amino acid modifications

Modified residue141Phosphothreonine By similarity
Modified residue151Phosphotyrosine By similarity
Modified residue1721Phosphothreonine; by CAK By similarity

Sequences

Sequence LengthMass (Da)Tools
Q38774 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: A8F577FB6DE72CE7

FASTA30534,298
        10         20         30         40         50         60 
MEKYEKLEKV GEGTYGKVYK ALEKSTGQVV ALKKTRLEMD EEGVPPTALR EVSLLQMLSQ 

        70         80         90        100        110        120 
SLYVVRLLSV EHVDCAKNGK PLLYLVFEYL DTDLKKFIDS HRKGPNPRPL PPQQIQSFLF 

       130        140        150        160        170        180 
QLCKGVSHCH AHGVLHRDLK PQNLLLDKDK GVLKIADLGL ARAFTVPLKS YTHEIVTLSY 

       190        200        210        220        230        240 
RAPEVLLGSS HYSTAVDMSS VGCIFAEMVR RQALFPGDSE FQQLLHIFRL LGTPSDEQWP 

       250        260        270        280        290        300 
GVSSLRDWHV YPQWEPQNSA PAVPSLGPDG LDLLTKTLKY DPADRISAKA ALDHPYFDTL 


DKSQF 

« Hide

References

[1]"Distinct classes of cdc2-related genes are differentially expressed during the cell division cycle in plants."
Fobert P.R., Gaudin V., Lunness P., Coen E.S., Doonan J.H.
Plant Cell 8:1465-1476(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Flower.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X97639 mRNA. Translation: CAA66235.1.
PIRT17117.

3D structure databases

ProteinModelPortalQ38774.
SMRQ38774. Positions 1-303.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Enzyme and pathway databases

BRENDA2.7.11.22. 376.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCDC2C_ANTMA
AccessionPrimary (citable) accession number: Q38774
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: November 1, 1996
Last modified: February 19, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families