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Q38773 (CDC2B_ANTMA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cell division control protein 2 homolog B

EC=2.7.11.22
EC=2.7.11.23
Gene names
Name:CDC2B
OrganismAntirrhinum majus (Garden snapdragon)
Taxonomic identifier4151 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeStreptophytaEmbryophytaTracheophytaSpermatophytaMagnoliophytaeudicotyledonsGunneridaePentapetalaeasteridslamiidsLamialesPlantaginaceaeAntirrhineaeAntirrhinum

Protein attributes

Sequence length280 AA.
Sequence statusFragment.
Protein existenceEvidence at transcript level

General annotation (Comments)

Function

Plays a key role in the control of the eukaryotic cell cycle.

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

ATP + [DNA-directed RNA polymerase] = ADP + [DNA-directed RNA polymerase] phosphate.

Enzyme regulation

Phosphorylation at Tyr-2 inactivates the enzyme, while phosphorylation at Thr-148 activates it By similarity.

Sequence similarities

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain‹1 – 280›280Cell division control protein 2 homolog B
PRO_0000085746

Regions

Domain‹1 – 274›274Protein kinase
Nucleotide binding‹1 – 5›5ATP By similarity

Sites

Active site1141Proton acceptor By similarity
Binding site201ATP By similarity

Amino acid modifications

Modified residue21Phosphotyrosine By similarity
Modified residue1481Phosphothreonine; by CAK By similarity

Experimental info

Non-terminal residue11

Sequences

Sequence LengthMass (Da)Tools
Q38773 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: EB4F3715A4FFE6CC

FASTA28032,167
        10         20         30         40         50         60 
AYGVVYKARD IETNEDIALK KIRLEQEDEG VPSTAIREIS LLKEMHHENI VNLKDVVHRE 

        70         80         90        100        110        120 
KRLYLVFEYL DLDLKKHMDS CPEFSQDLHM VKMFLCQILR GVAYCHSHRV LHRDLKPQNL 

       130        140        150        160        170        180 
LIDRGSNTIK LADFGLARAF GIPVRTFTHE VVTLWYRAPE VLLGSRHYST PVDVWSVGCI 

       190        200        210        220        230        240 
FAEMVNQKPL FPGDSEIDEL HKIFRIIGTP NEDIWPGVTS LPDFKSSFPK WPPKELATIV 

       250        260        270        280 
PNLGATGLDL LCKMLQLDPS KRITAKKALE HEYFKDIVLP 

« Hide

References

[1]"Distinct classes of cdc2-related genes are differentially expressed during the cell division cycle in plants."
Fobert P.R., Gaudin V., Lunness P., Coen E.S., Doonan J.H.
Plant Cell 8:1465-1476(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
Tissue: Flower.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X97638 mRNA. Translation: CAA66234.1.
PIRT17116.

3D structure databases

ProteinModelPortalQ38773.
SMRQ38773. Positions 2-280.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ38773.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCDC2B_ANTMA
AccessionPrimary (citable) accession number: Q38773
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1999
Last sequence update: November 1, 1996
Last modified: February 19, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families