ID Q385Y8_TRYB2 Unreviewed; 144 AA. AC Q385Y8; DT 22-NOV-2005, integrated into UniProtKB/TrEMBL. DT 22-NOV-2005, sequence version 1. DT 24-JAN-2024, entry version 85. DE RecName: Full=40S ribosomal protein S12 {ECO:0000256|RuleBase:RU000670}; GN ORFNames=Tb11.02.1830 {ECO:0000313|EMBL:EAN79393.1}; OS Trypanosoma brucei brucei (strain 927/4 GUTat10.1). OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina; OC Trypanosomatida; Trypanosomatidae; Trypanosoma. OX NCBI_TaxID=185431 {ECO:0000313|EMBL:EAN79393.1, ECO:0000313|Proteomes:UP000008524}; RN [1] {ECO:0000313|EMBL:EAN79393.1, ECO:0000313|Proteomes:UP000008524} RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. RC STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:EAN79393.1, RC ECO:0000313|Proteomes:UP000008524}; RX PubMed=16020726; DOI=10.1126/science.1112642; RA Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., RA Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U., RA Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B., RA Alsmark U.C., Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F., RA Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C., RA Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A., RA Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D., RA Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D., RA Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S., RA Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S., RA Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G., RA Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A., RA Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M., RA Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S., RA Walker D., Wanless D., Wang S., White B., White O., Whitehead S., RA Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E., RA Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E., RA Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.; RT "The genome of the African trypanosome Trypanosoma brucei."; RL Science 309:416-422(2005). RN [2] {ECO:0007829|PDB:4V8M} RP STRUCTURE BY ELECTRON MICROSCOPY (5.57 ANGSTROMS). RX PubMed=23395961; DOI=10.1038/nature11872; RA Hashem Y., des Georges A., Fu J., Buss S.N., Jossinet F., Jobe A., RA Zhang Q., Liao H.Y., Grassucci R.A., Bajaj C., Westhof E., RA Madison-Antenucci S., Frank J.; RT "High-resolution cryo-electron microscopy structure of the Trypanosoma RT brucei ribosome."; RL Nature 494:385-389(2013). CC -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eS12 family. CC {ECO:0000256|ARBA:ARBA00005824, ECO:0000256|RuleBase:RU000670}. CC --------------------------------------------------------------------------- CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms CC Distributed under the Creative Commons Attribution (CC BY 4.0) License CC --------------------------------------------------------------------------- DR EMBL; CH464491; EAN79393.1; -; Genomic_DNA. DR RefSeq; XP_828505.1; XM_823412.1. DR PDB; 4V8M; EM; 5.57 A; AF=1-144. DR PDBsum; 4V8M; -. DR AlphaFoldDB; Q385Y8; -. DR SMR; Q385Y8; -. DR IntAct; Q385Y8; 1. DR STRING; 185431.Q385Y8; -. DR PaxDb; 5691-EAN79393; -. DR GeneID; 3664867; -. DR KEGG; tbr:Tb11.02.1830; -. DR VEuPathDB; TriTrypDB:Tb927.11.4290; -. DR eggNOG; KOG3406; Eukaryota. DR InParanoid; Q385Y8; -. DR OrthoDB; 5045908at2759; -. DR Proteomes; UP000008524; Chromosome 11 Scaffold 1. DR GO; GO:0022627; C:cytosolic small ribosomal subunit; IBA:GO_Central. DR GO; GO:0003735; F:structural constituent of ribosome; IBA:GO_Central. DR GO; GO:0006412; P:translation; IEA:InterPro. DR Gene3D; 3.30.1330.30; -; 1. DR InterPro; IPR029064; Ribosomal_eL30-like_sf. DR InterPro; IPR004038; Ribosomal_eL8/eL30/eS12/Gad45. DR InterPro; IPR000530; Ribosomal_eS12. DR InterPro; IPR047860; Ribosomal_eS12_CS. DR PANTHER; PTHR11843; 40S RIBOSOMAL PROTEIN S12; 1. DR PANTHER; PTHR11843:SF0; 40S RIBOSOMAL PROTEIN S12; 1. DR Pfam; PF01248; Ribosomal_L7Ae; 1. DR PRINTS; PR00972; RIBSOMALS12E. DR SUPFAM; SSF55315; L30e-like; 1. DR PROSITE; PS01189; RIBOSOMAL_S12E; 1. PE 1: Evidence at protein level; KW 3D-structure {ECO:0007829|PDB:4V8M}; KW Reference proteome {ECO:0000313|Proteomes:UP000008524}; KW Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274, KW ECO:0000256|RuleBase:RU000670}; KW Ribosomal protein {ECO:0000256|ARBA:ARBA00022980, KW ECO:0000256|RuleBase:RU000670}. FT DOMAIN 32..125 FT /note="Ribosomal protein eL8/eL30/eS12/Gadd45" FT /evidence="ECO:0000259|Pfam:PF01248" SQ SEQUENCE 144 AA; 15869 MW; DCC8F18F0F37C1CB CRC64; MAEETSLVAD KVPEPAVIDA VADAMPDSLE DALRIVLMKA RETNGLICGL SEVTRALDRR TAHLCVLADD CEDEEYKKLV TALAKQNNID LVSMDEREKL AQWAGLTRMA ADGSVRKTLK CSCLAVRDFG ERTKALDYLL SQLQ //