ID   Q385E9_TRYB2            Unreviewed;       146 AA.
AC   Q385E9;
DT   22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2005, sequence version 1.
DT   27-MAR-2024, entry version 85.
DE   RecName: Full=Large ribosomal subunit protein eL28 {ECO:0000256|ARBA:ARBA00035223};
GN   ORFNames=Tb11.02.4050 {ECO:0000313|EMBL:EAN79580.1}, Tb11.02.4070
GN   {ECO:0000313|EMBL:EAN79582.1};
OS   Trypanosoma brucei brucei (strain 927/4 GUTat10.1).
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX   NCBI_TaxID=185431 {ECO:0000313|Proteomes:UP000008524};
RN   [1] {ECO:0000313|EMBL:EAN79582.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:EAN79582.1};
RX   PubMed=16020724; DOI=10.1126/science.1112181;
RA   El-Sayed N.M., Myler P.J., Blandin G., Berriman M., Crabtree J.,
RA   Aggarwal G., Caler E., Renauld H., Worthey E.A., Hertz-Fowler C.,
RA   Ghedin E., Peacock C., Bartholomeu D.C., Haas B.J., Tran A.N.,
RA   Wortman J.R., Alsmark U.C., Angiuoli S., Anupama A., Badger J.,
RA   Bringaud F., Cadag E., Carlton J.M., Cerqueira G.C., Creasy T.,
RA   Delcher A.L., Djikeng A., Embley T.M., Hauser C., Ivens A.C.,
RA   Kummerfeld S.K., Pereira-Leal J.B., Nilsson D., Peterson J., Salzberg S.L.,
RA   Shallom J., Silva J.C., Sundaram J., Westenberger S., White O.,
RA   Melville S.E., Donelson J.E., Andersson B., Stuart K.D., Hall N.;
RT   "Comparative genomics of trypanosomatid parasitic protozoa.";
RL   Science 309:404-409(2005).
RN   [2] {ECO:0000313|EMBL:EAN79582.1, ECO:0000313|Proteomes:UP000008524}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:EAN79582.1,
RC   ECO:0000313|Proteomes:UP000008524};
RX   PubMed=16020726; DOI=10.1126/science.1112642;
RA   Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H.,
RA   Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U.,
RA   Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B.,
RA   Alsmark U.C., Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F.,
RA   Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C.,
RA   Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A.,
RA   Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D.,
RA   Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D.,
RA   Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S.,
RA   Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S.,
RA   Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G.,
RA   Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A.,
RA   Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M.,
RA   Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S.,
RA   Walker D., Wanless D., Wang S., White B., White O., Whitehead S.,
RA   Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E.,
RA   Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E.,
RA   Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.;
RT   "The genome of the African trypanosome Trypanosoma brucei.";
RL   Science 309:416-422(2005).
RN   [3] {ECO:0007829|PDB:4V8M}
RP   STRUCTURE BY ELECTRON MICROSCOPY (5.57 ANGSTROMS).
RX   PubMed=23395961; DOI=10.1038/nature11872;
RA   Hashem Y., des Georges A., Fu J., Buss S.N., Jossinet F., Jobe A.,
RA   Zhang Q., Liao H.Y., Grassucci R.A., Bajaj C., Westhof E.,
RA   Madison-Antenucci S., Frank J.;
RT   "High-resolution cryo-electron microscopy structure of the Trypanosoma
RT   brucei ribosome.";
RL   Nature 494:385-389(2013).
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL28 family.
CC       {ECO:0000256|ARBA:ARBA00007926}.
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DR   EMBL; CH464491; EAN79580.1; -; Genomic_DNA.
DR   EMBL; CH464491; EAN79582.1; -; Genomic_DNA.
DR   RefSeq; XP_828692.1; XM_823599.1.
DR   RefSeq; XP_828694.1; XM_823601.1.
DR   PDB; 4V8M; EM; 5.57 A; Bc=1-146.
DR   PDBsum; 4V8M; -.
DR   AlphaFoldDB; Q385E9; -.
DR   EMDB; EMD-17208; -.
DR   EMDB; EMD-17212; -.
DR   IntAct; Q385E9; 1.
DR   STRING; 185431.Q385E9; -.
DR   PaxDb; 5691-EAN79580; -.
DR   GeneID; 3665102; -.
DR   GeneID; 3665104; -.
DR   KEGG; tbr:Tb11.02.4050; -.
DR   KEGG; tbr:Tb11.02.4070; -.
DR   VEuPathDB; TriTrypDB:Tb927.11.6180; -.
DR   VEuPathDB; TriTrypDB:Tb927.11.6200; -.
DR   eggNOG; ENOG502SBM7; Eukaryota.
DR   InParanoid; Q385E9; -.
DR   OrthoDB; 155768at2759; -.
DR   Proteomes; UP000008524; Chromosome 11 Scaffold 1.
DR   GO; GO:0005737; C:cytoplasm; IDA:GeneDB.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0005840; C:ribosome; ISM:GeneDB.
DR   GO; GO:0003729; F:mRNA binding; IDA:GeneDB.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISM:GeneDB.
DR   GO; GO:0006412; P:translation; ISM:GeneDB.
DR   Gene3D; 3.30.390.110; -; 1.
DR   InterPro; IPR002672; Ribosomal_eL28.
DR   InterPro; IPR029004; Ribosomal_eL28/Mak16.
DR   PANTHER; PTHR10544; 60S RIBOSOMAL PROTEIN L28; 1.
DR   PANTHER; PTHR10544:SF0; 60S RIBOSOMAL PROTEIN L28; 1.
DR   Pfam; PF01778; Ribosomal_L28e; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:4V8M};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008524};
KW   Ribonucleoprotein {ECO:0000313|EMBL:EAN79582.1};
KW   Ribosomal protein {ECO:0000313|EMBL:EAN79582.1}.
FT   DOMAIN          7..114
FT                   /note="Ribosomal eL28/Mak16"
FT                   /evidence="ECO:0000259|Pfam:PF01778"
SQ   SEQUENCE   146 AA;  16861 MW;  3D8E8356F46F7420 CRC64;
     MTHSTDLQWL LVRQNSKFLQ KRNGIRLSSD PFNNNANWTK RQSGFLNTKA AVIKTKGDRI
     LLTTKSGDTN NKPKLMYKKT VMEPGVKSSV VKRAVADIRP DLAKMAYRRA RKMACTITRM
     KKVCAARKER SSKMHFHRKT VRPKRN
//