Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q383I8 (Q383I8_TRYB2) Unreviewed, UniProtKB/TrEMBL

Last modified May 14, 2014. Version 49. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
40S ribosomal protein SA HAMAP-Rule MF_03015
Gene names
ORF Names:Tb11.01.2680 EMBL EAN80043.1
OrganismTrypanosoma brucei brucei (strain 927/4 GUTat10.1) [Reference proteome]
Taxonomic identifier999953 [NCBI]
Taxonomic lineageEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosoma

Protein attributes

Sequence length277 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits By similarity. HAMAP-Rule MF_03015

Subunit structure

Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with ribosomal protein S21 By similarity. HAMAP-Rule MF_03015

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_03015.

Sequence similarities

Belongs to the ribosomal protein S2P family. HAMAP-Rule MF_03015 RuleBase RU003631

Sequences

Sequence LengthMass (Da)Tools
Q383I8 [UniParc].

Last modified November 22, 2005. Version 1.
Checksum: B746058506B77D3B

FASTA27731,354
        10         20         30         40         50         60 
MTETSRRDLI FLVLSPFSPS LSSKALRNSH TRNMTSVSSG AKVLRMKESD VQKLLAMHCH 

        70         80         90        100        110        120 
LGTKNSSSAM KKYIHGRTSD GTNIIDIHMT WEKLILAARV IAAVENPQDV TVCSTRLFGQ 

       130        140        150        160        170        180 
RAIFKFSQLV GTSFLGGRFI PGTFTNQIQK KFMQPRVLVV TDPRTDHQAL REASLVNIPV 

       190        200        210        220        230        240 
IAFCDTDAPL EFVDIAIPCN NRGRHSISMM YWLLAREVLR LRGTIPRSVP WEVKVDLFFY 

       250        260        270 
RDPEEALKQE EATAAAEVHE EADEGYGWVE RDNTWEQ 

« Hide

References

« Hide 'large scale' references
[1]"The genome of the African trypanosome Trypanosoma brucei."
Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U., Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B., Alsmark U.C.M. expand/collapse author list , Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F., Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C., Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A., Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D., Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D., Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S., Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S., Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G., Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A., Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M., Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S., Walker D., Wanless D., Wang S., White B., White O., Whitehead S., Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E., Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E., Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.A.
Science 309:416-422(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: 927/4 GUTat10.1 EMBL EAN80043.1.
[2]"High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome."
Hashem Y., des Georges A., Fu J., Buss S.N., Jossinet F., Jobe A., Zhang Q., Liao H.Y., Grassucci R.A., Bajaj C., Westhof E., Madison-Antenucci S., Frank J.
Nature 494:385-389(2013) [PubMed] [Europe PMC] [Abstract]
Cited for: STRUCTURE BY ELECTRON MICROSCOPY (5.57 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CH464491 Genomic DNA. Translation: EAN80043.1.
RefSeqXP_829155.1. XM_824062.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
3ZEYelectron microscopy5.57C1-277[»]
ProteinModelPortalQ383I8.
SMRQ383I8. Positions 45-241.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5691.Tb11.01.2680.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsEAN80043; EAN80043; Tb11.01.2680.
GeneID3665659.
KEGGtbr:Tb11.01.2680.

Phylogenomic databases

eggNOGCOG0052.
HOGENOMHOG000232073.
KOK02998.

Family and domain databases

HAMAPMF_03015. Ribosomal_S2_euk.
InterProIPR001865. Ribosomal_S2.
IPR018130. Ribosomal_S2_CS.
IPR027498. Ribosomal_S2_euk.
IPR005707. Ribosomal_S2_euk/arc.
IPR023591. Ribosomal_S2_flav_dom.
[Graphical view]
PANTHERPTHR11489. PTHR11489. 1 hit.
PfamPF00318. Ribosomal_S2. 2 hits.
[Graphical view]
PRINTSPR00395. RIBOSOMALS2.
SUPFAMSSF52313. SSF52313. 1 hit.
TIGRFAMsTIGR01012. Sa_S2_E_A. 1 hit.
PROSITEPS00963. RIBOSOMAL_S2_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ383I8_TRYB2
AccessionPrimary (citable) accession number: Q383I8
Entry history
Integrated into UniProtKB/TrEMBL: November 22, 2005
Last sequence update: November 22, 2005
Last modified: May 14, 2014
This is version 49 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)