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Q383I8

- Q383I8_TRYB2

UniProt

Q383I8 - Q383I8_TRYB2

Protein

40S ribosomal protein SA

Gene

Tb11.01.2680

Organism
Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Status
Unreviewed - Annotation score: 2 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 50 (01 Oct 2014)
      Sequence version 1 (22 Nov 2005)
      Previous versions | rss
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    Functioni

    Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.UniRule annotation

    GO - Molecular functioni

    1. structural constituent of ribosome Source: UniProtKB-HAMAP

    GO - Biological processi

    1. ribosomal small subunit assembly Source: UniProtKB-HAMAP
    2. translation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Ribonucleoprotein, Ribosomal proteinUniRule annotationSAAS annotationImported

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    40S ribosomal protein SAUniRule annotation
    Gene namesi
    ORF Names:Tb11.01.2680Imported
    OrganismiTrypanosoma brucei brucei (strain 927/4 GUTat10.1)Imported
    Taxonomic identifieri999953 [NCBI]
    Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosoma
    ProteomesiUP000008524: Chromosome 11 Scaffold 1

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytosolic small ribosomal subunit Source: UniProtKB-HAMAP

    Keywords - Cellular componenti

    CytoplasmUniRule annotationSAAS annotation

    Interactioni

    Subunit structurei

    Component of the small ribosomal subunit. Mature ribosomes consist of a small (40S) and a large (60S) subunit. The 40S subunit contains about 33 different proteins and 1 molecule of RNA (18S). The 60S subunit contains about 49 different proteins and 3 molecules of RNA (25S, 5.8S and 5S). Interacts with ribosomal protein S21.UniRule annotation

    Protein-protein interaction databases

    STRINGi5691.Tb11.01.2680.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    3ZEYelectron microscopy5.57C1-277[»]
    ProteinModelPortaliQ383I8.
    SMRiQ383I8. Positions 45-241.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the ribosomal protein S2P family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0052.
    HOGENOMiHOG000232073.
    KOiK02998.

    Family and domain databases

    HAMAPiMF_03015. Ribosomal_S2_euk.
    InterProiIPR001865. Ribosomal_S2.
    IPR018130. Ribosomal_S2_CS.
    IPR027498. Ribosomal_S2_euk.
    IPR005707. Ribosomal_S2_euk/arc.
    IPR023591. Ribosomal_S2_flav_dom.
    [Graphical view]
    PANTHERiPTHR11489. PTHR11489. 1 hit.
    PfamiPF00318. Ribosomal_S2. 2 hits.
    [Graphical view]
    PRINTSiPR00395. RIBOSOMALS2.
    SUPFAMiSSF52313. SSF52313. 1 hit.
    TIGRFAMsiTIGR01012. Sa_S2_E_A. 1 hit.
    PROSITEiPS00963. RIBOSOMAL_S2_2. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q383I8-1 [UniParc]FASTAAdd to Basket

    « Hide

    MTETSRRDLI FLVLSPFSPS LSSKALRNSH TRNMTSVSSG AKVLRMKESD    50
    VQKLLAMHCH LGTKNSSSAM KKYIHGRTSD GTNIIDIHMT WEKLILAARV 100
    IAAVENPQDV TVCSTRLFGQ RAIFKFSQLV GTSFLGGRFI PGTFTNQIQK 150
    KFMQPRVLVV TDPRTDHQAL REASLVNIPV IAFCDTDAPL EFVDIAIPCN 200
    NRGRHSISMM YWLLAREVLR LRGTIPRSVP WEVKVDLFFY RDPEEALKQE 250
    EATAAAEVHE EADEGYGWVE RDNTWEQ 277
    Length:277
    Mass (Da):31,354
    Last modified:November 22, 2005 - v1
    Checksum:iB746058506B77D3B
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH464491 Genomic DNA. Translation: EAN80043.1.
    RefSeqiXP_829155.1. XM_824062.1.

    Genome annotation databases

    EnsemblProtistsiEAN80043; EAN80043; Tb11.01.2680.
    GeneIDi3665659.
    KEGGitbr:Tb11.01.2680.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CH464491 Genomic DNA. Translation: EAN80043.1 .
    RefSeqi XP_829155.1. XM_824062.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    3ZEY electron microscopy 5.57 C 1-277 [» ]
    ProteinModelPortali Q383I8.
    SMRi Q383I8. Positions 45-241.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5691.Tb11.01.2680.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblProtistsi EAN80043 ; EAN80043 ; Tb11.01.2680 .
    GeneIDi 3665659.
    KEGGi tbr:Tb11.01.2680.

    Phylogenomic databases

    eggNOGi COG0052.
    HOGENOMi HOG000232073.
    KOi K02998.

    Family and domain databases

    HAMAPi MF_03015. Ribosomal_S2_euk.
    InterProi IPR001865. Ribosomal_S2.
    IPR018130. Ribosomal_S2_CS.
    IPR027498. Ribosomal_S2_euk.
    IPR005707. Ribosomal_S2_euk/arc.
    IPR023591. Ribosomal_S2_flav_dom.
    [Graphical view ]
    PANTHERi PTHR11489. PTHR11489. 1 hit.
    Pfami PF00318. Ribosomal_S2. 2 hits.
    [Graphical view ]
    PRINTSi PR00395. RIBOSOMALS2.
    SUPFAMi SSF52313. SSF52313. 1 hit.
    TIGRFAMsi TIGR01012. Sa_S2_E_A. 1 hit.
    PROSITEi PS00963. RIBOSOMAL_S2_2. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome of the African trypanosome Trypanosoma brucei."
      Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U., Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B., Alsmark U.C.M.
      , Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F., Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C., Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A., Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D., Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D., Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S., Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S., Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G., Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A., Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M., Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S., Walker D., Wanless D., Wang S., White B., White O., Whitehead S., Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E., Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E., Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.A.
      Science 309:416-422(2005) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: 927/4 GUTat10.1Imported.
    2. "High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome."
      Hashem Y., des Georges A., Fu J., Buss S.N., Jossinet F., Jobe A., Zhang Q., Liao H.Y., Grassucci R.A., Bajaj C., Westhof E., Madison-Antenucci S., Frank J.
      Nature 494:385-389(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: STRUCTURE BY ELECTRON MICROSCOPY (5.57 ANGSTROMS).

    Entry informationi

    Entry nameiQ383I8_TRYB2
    AccessioniPrimary (citable) accession number: Q383I8
    Entry historyi
    Integrated into UniProtKB/TrEMBL: November 22, 2005
    Last sequence update: November 22, 2005
    Last modified: October 1, 2014
    This is version 50 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3