ID   Q382C4_TRYB2            Unreviewed;       179 AA.
AC   Q382C4;
DT   22-NOV-2005, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2005, sequence version 1.
DT   27-MAR-2024, entry version 105.
DE   RecName: Full=60S ribosomal protein L18a {ECO:0000256|PIRNR:PIRNR002190};
GN   ORFNames=Tb10.70.3510 {ECO:0000313|EMBL:EAN77804.1}, Tb11.01.5720
GN   {ECO:0000313|EMBL:EAN80357.1};
OS   Trypanosoma brucei brucei (strain 927/4 GUTat10.1).
OC   Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC   Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX   NCBI_TaxID=185431 {ECO:0000313|Proteomes:UP000008524};
RN   [1] {ECO:0000313|EMBL:EAN80357.1}
RP   NUCLEOTIDE SEQUENCE.
RC   STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:EAN80357.1};
RX   PubMed=16020724; DOI=10.1126/science.1112181;
RA   El-Sayed N.M., Myler P.J., Blandin G., Berriman M., Crabtree J.,
RA   Aggarwal G., Caler E., Renauld H., Worthey E.A., Hertz-Fowler C.,
RA   Ghedin E., Peacock C., Bartholomeu D.C., Haas B.J., Tran A.N.,
RA   Wortman J.R., Alsmark U.C., Angiuoli S., Anupama A., Badger J.,
RA   Bringaud F., Cadag E., Carlton J.M., Cerqueira G.C., Creasy T.,
RA   Delcher A.L., Djikeng A., Embley T.M., Hauser C., Ivens A.C.,
RA   Kummerfeld S.K., Pereira-Leal J.B., Nilsson D., Peterson J., Salzberg S.L.,
RA   Shallom J., Silva J.C., Sundaram J., Westenberger S., White O.,
RA   Melville S.E., Donelson J.E., Andersson B., Stuart K.D., Hall N.;
RT   "Comparative genomics of trypanosomatid parasitic protozoa.";
RL   Science 309:404-409(2005).
RN   [2] {ECO:0000313|EMBL:EAN80357.1, ECO:0000313|Proteomes:UP000008524}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=927/4 GUTat10.1 {ECO:0000313|EMBL:EAN80357.1,
RC   ECO:0000313|Proteomes:UP000008524};
RX   PubMed=16020726; DOI=10.1126/science.1112642;
RA   Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H.,
RA   Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U.,
RA   Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B.,
RA   Alsmark U.C., Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F.,
RA   Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C.,
RA   Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A.,
RA   Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D.,
RA   Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D.,
RA   Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S.,
RA   Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S.,
RA   Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G.,
RA   Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A.,
RA   Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M.,
RA   Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S.,
RA   Walker D., Wanless D., Wang S., White B., White O., Whitehead S.,
RA   Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E.,
RA   Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E.,
RA   Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.;
RT   "The genome of the African trypanosome Trypanosoma brucei.";
RL   Science 309:416-422(2005).
RN   [3] {ECO:0007829|PDB:4V8M}
RP   STRUCTURE BY ELECTRON MICROSCOPY (5.57 ANGSTROMS).
RX   PubMed=23395961; DOI=10.1038/nature11872;
RA   Hashem Y., des Georges A., Fu J., Buss S.N., Jossinet F., Jobe A.,
RA   Zhang Q., Liao H.Y., Grassucci R.A., Bajaj C., Westhof E.,
RA   Madison-Antenucci S., Frank J.;
RT   "High-resolution cryo-electron microscopy structure of the Trypanosoma
RT   brucei ribosome.";
RL   Nature 494:385-389(2013).
CC   -!- SIMILARITY: Belongs to the eukaryotic ribosomal protein eL20 family.
CC       {ECO:0000256|ARBA:ARBA00009362, ECO:0000256|PIRNR:PIRNR002190}.
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DR   EMBL; CM000208; EAN77804.1; -; Genomic_DNA.
DR   EMBL; CH464491; EAN80357.1; -; Genomic_DNA.
DR   RefSeq; XP_822632.1; XM_817539.1.
DR   RefSeq; XP_829469.1; XM_824376.1.
DR   PDB; 4V8M; EM; 5.57 A; BS=1-179.
DR   PDBsum; 4V8M; -.
DR   AlphaFoldDB; Q382C4; -.
DR   EMDB; EMD-17208; -.
DR   EMDB; EMD-17212; -.
DR   IntAct; Q382C4; 1.
DR   STRING; 185431.Q382C4; -.
DR   PaxDb; 5691-EAN77804; -.
DR   GeneID; 3662334; -.
DR   GeneID; 3665177; -.
DR   KEGG; tbr:Tb10.70.3510; -.
DR   KEGG; tbr:Tb11.01.5720; -.
DR   VEuPathDB; TriTrypDB:Tb927.10.3840; -.
DR   VEuPathDB; TriTrypDB:Tb927.11.14130; -.
DR   eggNOG; KOG0829; Eukaryota.
DR   InParanoid; Q382C4; -.
DR   OMA; CIFAKND; -.
DR   OrthoDB; 167315at2759; -.
DR   Proteomes; UP000008524; Chromosome 10.
DR   Proteomes; UP000008524; Chromosome 11 Scaffold 1.
DR   GO; GO:0005737; C:cytoplasm; IDA:GeneDB.
DR   GO; GO:0022625; C:cytosolic large ribosomal subunit; IBA:GO_Central.
DR   GO; GO:0005730; C:nucleolus; IDA:GeneDB.
DR   GO; GO:0005840; C:ribosome; ISM:GeneDB.
DR   GO; GO:0003729; F:mRNA binding; IDA:GeneDB.
DR   GO; GO:0003735; F:structural constituent of ribosome; ISM:GeneDB.
DR   GO; GO:0006412; P:translation; ISM:GeneDB.
DR   Gene3D; 3.10.20.10; -; 2.
DR   HAMAP; MF_00273; Ribosomal_L18Ae; 1.
DR   InterPro; IPR028877; Ribosomal_eL20.
DR   InterPro; IPR023573; Ribosomal_eL20_dom.
DR   InterPro; IPR021138; Ribosomal_eL20_eukaryotes.
DR   PANTHER; PTHR10052; 60S RIBOSOMAL PROTEIN L18A; 1.
DR   PANTHER; PTHR10052:SF1; 60S RIBOSOMAL PROTEIN L18A; 1.
DR   Pfam; PF01775; Ribosomal_L18A; 1.
DR   PIRSF; PIRSF002190; Ribosomal_L18a; 1.
DR   SUPFAM; SSF160374; RplX-like; 1.
PE   1: Evidence at protein level;
KW   3D-structure {ECO:0007829|PDB:4V8M};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008524};
KW   Ribonucleoprotein {ECO:0000256|ARBA:ARBA00023274,
KW   ECO:0000256|PIRNR:PIRNR002190};
KW   Ribosomal protein {ECO:0000256|ARBA:ARBA00022980,
KW   ECO:0000256|PIRNR:PIRNR002190}.
FT   DOMAIN          7..129
FT                   /note="Large ribosomal subunit protein eL20"
FT                   /evidence="ECO:0000259|Pfam:PF01775"
SQ   SEQUENCE   179 AA;  20904 MW;  57D900A212BE50D0 CRC64;
     MVRPHLRHYC VVGRETPSEK NPQPTVYKFE VFAPNFVVAK SRFWRMMREK NKVKSTHGDV
     LSCKVVKDRK LAARNYSVDI AYYSQRCGYT HMVKEFRDVC KAGAVSQAYN DLASRHRARY
     HNIEVLGVKS IPNHEVRRLN VAQFHPHNLS FPLLQRRVKA PRKDRVIFVK KNSKRAVVA
//