Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

C-14 sterol reductase, putative

Gene

Tb11.01.7170

Organism
Trypanosoma brucei brucei (strain 927/4 GUTat10.1)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
C-14 sterol reductase, putativeImported
Gene namesi
ORF Names:Tb11.01.7170Imported
OrganismiTrypanosoma brucei brucei (strain 927/4 GUTat10.1)Imported
Taxonomic identifieri185431 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosoma
Proteomesi
  • UP000008524 Componenti: Chromosome 11 Scaffold 1

Organism-specific databases

EuPathDBiTriTrypDB:Tb927.11.15530.

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei50 – 6920HelicalSequence analysisAdd
BLAST
Transmembranei98 – 11720HelicalSequence analysisAdd
BLAST
Transmembranei137 – 15822HelicalSequence analysisAdd
BLAST
Transmembranei170 – 19122HelicalSequence analysisAdd
BLAST
Transmembranei294 – 31219HelicalSequence analysisAdd
BLAST
Transmembranei324 – 34320HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

HOGENOMiHOG000193296.
InParanoidiQ381N2.
KOiK00222.

Family and domain databases

InterProiIPR001171. Ergosterol_biosynth_ERG4_ERG24.
IPR018083. Sterol_reductase_CS.
[Graphical view]
PfamiPF01222. ERG4_ERG24. 1 hit.
[Graphical view]
PROSITEiPS01017. STEROL_REDUCT_1. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q381N2-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MPPRSRKGTK SRSASPAPRT PGRTKKSPVT PRTKTPVTNK NRSYEWGGPL
60 70 80 90 100
GALGMVVLLP LTVIGLNVLC SENSCSVHNV WDLPAMILLA LDVGVPRLVL
110 120 130 140 150
ALGVELLWMA FHALLYITPV GKQVKGVKLS DGTCLTYNIN ALHVFTLVHA
160 170 180 190 200
ILGSMHYADV IRLAWLADMF MPLMVAAIII SVFMSIVLYV ASFRSSQVSF
210 220 230 240 250
SPGGNTGNYL YDFWVGRELN PRTGSLDWKF MCELRPGLIG WSVLNWAFVA
260 270 280 290 300
KAMEVGTCSP SIIVVALLES FYVLDGLLYE EGNLTMMDIV HDGFGFMLCF
310 320 330 340 350
GDLAWVPFTY TLKAKFLAYH ASQLSYMHVG ICAAVALVGY AVFRGSNNQK
360 370 380 390 400
SRFRQNPKDP ANAALKVMHT SSGKSLIVSG YWGVCRHPNY VGDWLMTLSW
410 420 430 440 450
SALTGFTEPL PYFQPVYFAL LLIHRQLRDE EQMREKYGAE DMHKFHRIVR

YRLIPYVY
Length:458
Mass (Da):51,183
Last modified:November 22, 2005 - v1
Checksum:i71465931ECF166CF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH464491 Genomic DNA. Translation: EAN80499.1.
RefSeqiXP_829611.1. XM_824518.1.

Genome annotation databases

EnsemblProtistsiEAN80499; EAN80499; Tb11.01.7170.
GeneDBiTb927.11.15530:pep.
GeneIDi3664443.
KEGGitbr:Tb11.01.7170.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CH464491 Genomic DNA. Translation: EAN80499.1.
RefSeqiXP_829611.1. XM_824518.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiEAN80499; EAN80499; Tb11.01.7170.
GeneDBiTb927.11.15530:pep.
GeneIDi3664443.
KEGGitbr:Tb11.01.7170.

Organism-specific databases

EuPathDBiTriTrypDB:Tb927.11.15530.

Phylogenomic databases

HOGENOMiHOG000193296.
InParanoidiQ381N2.
KOiK00222.

Family and domain databases

InterProiIPR001171. Ergosterol_biosynth_ERG4_ERG24.
IPR018083. Sterol_reductase_CS.
[Graphical view]
PfamiPF01222. ERG4_ERG24. 1 hit.
[Graphical view]
PROSITEiPS01017. STEROL_REDUCT_1. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "The genome of the African trypanosome Trypanosoma brucei."
    Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U., Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B., Alsmark U.C.M.
    , Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F., Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C., Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A., Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D., Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D., Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S., Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S., Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G., Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A., Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M., Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S., Walker D., Wanless D., Wang S., White B., White O., Whitehead S., Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E., Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E., Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.A.
    Science 309:416-422(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: 927/4 GUTat10.1Imported.

Entry informationi

Entry nameiQ381N2_TRYB2
AccessioniPrimary (citable) accession number: Q381N2
Entry historyi
Integrated into UniProtKB/TrEMBL: November 22, 2005
Last sequence update: November 22, 2005
Last modified: February 17, 2016
This is version 45 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.