Q381N2 (Q381N2_TRYB2) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
C-14 sterol reductase, putative EMBL EAN80499.1

Gene names

ORF Names:

Tb11.01.7170 EMBL EAN80499.1

Organism

Trypanosoma brucei brucei (strain 927/4 GUTat10.1) [Reference proteome]

Taxonomic identifier

999953 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Trypanosoma › Trypanozoon › Trypanosoma brucei › Trypanosoma brucei brucei

Protein attributes

Sequence length	458 AA.
Sequence status	Complete.
Protein existence	Predicted

Ontologies

Keywords
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Cellular_component	membrane Inferred from electronic annotation. Source: InterPro
Molecular_function	oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q381N2 [UniParc]. Last modified November 22, 2005. Version 1. Checksum: 71465931ECF166CF	FASTA	458	51,183
	10 20 30 40 50 60 MPPRSRKGTK SRSASPAPRT PGRTKKSPVT PRTKTPVTNK NRSYEWGGPL GALGMVVLLP 70 80 90 100 110 120 LTVIGLNVLC SENSCSVHNV WDLPAMILLA LDVGVPRLVL ALGVELLWMA FHALLYITPV 130 140 150 160 170 180 GKQVKGVKLS DGTCLTYNIN ALHVFTLVHA ILGSMHYADV IRLAWLADMF MPLMVAAIII 190 200 210 220 230 240 SVFMSIVLYV ASFRSSQVSF SPGGNTGNYL YDFWVGRELN PRTGSLDWKF MCELRPGLIG 250 260 270 280 290 300 WSVLNWAFVA KAMEVGTCSP SIIVVALLES FYVLDGLLYE EGNLTMMDIV HDGFGFMLCF 310 320 330 340 350 360 GDLAWVPFTY TLKAKFLAYH ASQLSYMHVG ICAAVALVGY AVFRGSNNQK SRFRQNPKDP 370 380 390 400 410 420 ANAALKVMHT SSGKSLIVSG YWGVCRHPNY VGDWLMTLSW SALTGFTEPL PYFQPVYFAL 430 440 450 LLIHRQLRDE EQMREKYGAE DMHKFHRIVR YRLIPYVY

References

[1]

"The genome of the African trypanosome Trypanosoma brucei." Berriman M., Ghedin E., Hertz-Fowler C., Blandin G., Renauld H., Bartholomeu D.C., Lennard N.J., Caler E., Hamlin N.E., Haas B., Bohme U., Hannick L., Aslett M.A., Shallom J., Marcello L., Hou L., Wickstead B., Alsmark U.C.M. , Arrowsmith C., Atkin R.J., Barron A.J., Bringaud F., Brooks K., Carrington M., Cherevach I., Chillingworth T.J., Churcher C., Clark L.N., Corton C.H., Cronin A., Davies R.M., Doggett J., Djikeng A., Feldblyum T., Field M.C., Fraser A., Goodhead I., Hance Z., Harper D., Harris B.R., Hauser H., Hostetler J., Ivens A., Jagels K., Johnson D., Johnson J., Jones K., Kerhornou A.X., Koo H., Larke N., Landfear S., Larkin C., Leech V., Line A., Lord A., Macleod A., Mooney P.J., Moule S., Martin D.M., Morgan G.W., Mungall K., Norbertczak H., Ormond D., Pai G., Peacock C.S., Peterson J., Quail M.A., Rabbinowitsch E., Rajandream M.A., Reitter C., Salzberg S.L., Sanders M., Schobel S., Sharp S., Simmonds M., Simpson A.J., Tallon L., Turner C.M., Tait A., Tivey A.R., Van Aken S., Walker D., Wanless D., Wang S., White B., White O., Whitehead S., Woodward J., Wortman J., Adams M.D., Embley T.M., Gull K., Ullu E., Barry J.D., Fairlamb A.H., Opperdoes F., Barrell B.G., Donelson J.E., Hall N., Fraser C.M., Melville S.E., El-Sayed N.M.A. Science 309:416-422(2005) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: 927/4 GUTat10.1 EMBL EAN80499.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CH464491 Genomic DNA. Translation: EAN80499.1.
RefSeq	XP_829611.1. XM_824518.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	5691.Tb11.01.7170.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblProtists	EAN80499; EAN80499; Tb11.01.7170.
GeneID	3664443.
KEGG	tbr:Tb11.01.7170.
Phylogenomic databases
eggNOG	NOG72042.
HOGENOM	HOG000193296.
KO	K00222.
ProtClustDB	CLSZ2438122.
Family and domain databases
InterPro	IPR001171. Ergosterol_biosynth_ERG4_ERG24. IPR018083. Sterol_reductase_CS. [Graphical view]
Pfam	PF01222. ERG4_ERG24. 1 hit. [Graphical view]
PROSITE	PS01017. STEROL_REDUCT_1. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q381N2_TRYB2

Accession

Primary (citable) accession number: Q381N2

Entry history

Integrated into UniProtKB/TrEMBL:	November 22, 2005
Last sequence update:	November 22, 2005
Last modified:	April 3, 2013
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)