Q38135 (ALYS_BPR1T) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names	Recommended name: N-acetylmuramoyl-L-alanine amidase EC=3.5.1.28
Organism	Lactococcus phage r1t (Bacteriophage r1t)
Taxonomic identifier	43685 [NCBI]
Taxonomic lineage	Viruses › dsDNA viruses, no RNA stage › Caudovirales › Siphoviridae
Virus host	Lactococcus lactis subsp. cremoris (Streptococcus cremoris) [TaxID: 1359]

Protein attributes

Sequence length	270 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Hydrolyzes the link between N-acetylmuramoyl residues and L-amino acid residues in certain cell-wall glycopeptides.
Subcellular location	Secreted Potential.
Sequence similarities	Belongs to the N-acetylmuramoyl-L-alanine amidase 2 family.

Ontologies

Keywords
Biological process	Cell wall biogenesis/degradation
Cellular component	Secreted
Molecular function	Hydrolase
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan catabolic process Inferred from electronic annotation. Source: InterPro
Cellular component	extracellular region Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	N-acetylmuramoyl-L-alanine amidase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 270	270	N-acetylmuramoyl-L-alanine amidase		PRO_0000164407

Sequences

	Sequence		Length	Mass (Da)
	Q38135 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: 80A5E38F7F2A6675	FASTA	270	30,214
	10 20 30 40 50 60 MTIYDKTFLL GTGQGSSQKA SNRYIVIHDT ANDNNQGDNS ATNEASYMHN NWQNAYTHAI 70 80 90 100 110 120 AGWDKVYLVG EPGYVAYGAG SPANERSPFQ IELSHYSDPA KQRSSYINYI NAVREQAKVF 130 140 150 160 170 180 GIPLTLDGAG NGIKTHKWVS DNLWGDHQDP YSYLTRIGIS KDQLAKDLAN GIGGASKSNQ 190 200 210 220 230 240 SNNDDSTHAI NYTPNMEEKE MTYLIFAKDT KRWYITNGIE IRYIKTGRVL GNYQNQWLKF 250 260 270 KLPVDTMFQA EVDKEFGTGA TNPNRDISKG

References

[1]	"Sequence analysis and molecular characterization of the temperate lactococcal bacteriophage r1t." van Sinderen D., Karsens H., Kok J., Terpstra P., Ruiters M.H., Venema G., Nauta A. Mol. Microbiol. 19:1343-1355(1996) [PubMed: 8730875] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Cross-references

Sequence databases
EMBL GenBank DDBJ	U38906 Genomic DNA. Translation: AAB18724.1.
RefSeq	NP_695077.1. NC_004302.1.
3D structure databases
ProteinModelPortal	Q38135.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	955499.
Family and domain databases
InterPro	IPR002502. Amidase_domain. [Graphical view]
Pfam	PF01510. Amidase_2. 1 hit. [Graphical view]
SMART	SM00644. Ami_2. 1 hit. [Graphical view]
SUPFAM	SSF55846. Amidase_2. 1 hit.
ProtoNet	Search...

Entry information

Entry name

ALYS_BPR1T

Accession

Primary (citable) accession number: Q38135

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	November 1, 1996
Last modified:	September 21, 2011
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Viral Protein Annotation Program