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Protein

Ribulose bisphosphate carboxylase large chain 2

Gene

cbbL2

Organism
Rhodopseudomonas palustris (strain BisB5)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

RuBisCO catalyzes two reactions: the carboxylation of D-ribulose 1,5-bisphosphate, the primary event in carbon dioxide fixation, as well as the oxidative fragmentation of the pentose substrate. Both reactions occur simultaneously and in competition at the same active site.UniRule annotation

Miscellaneous

The basic functional RuBisCO is composed of a large chain homodimer in a "head-to-tail" conformation. In form I RuBisCO this homodimer is arranged in a barrel-like tetramer with the small subunits forming a tetrameric "cap" on each end of the "barrel".UniRule annotation

Catalytic activityi

2 3-phospho-D-glycerate + 2 H+ = D-ribulose 1,5-bisphosphate + CO2 + H2O.UniRule annotation
3-phospho-D-glycerate + 2-phosphoglycolate = D-ribulose 1,5-bisphosphate + O2.UniRule annotation

Cofactori

Mg2+UniRule annotationNote: Binds 1 Mg2+ ion per subunit.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei124Substrate; in homodimeric partnerUniRule annotation1
Binding sitei174SubstrateUniRule annotation1
Active sitei176Proton acceptorUniRule annotation1
Binding sitei178SubstrateUniRule annotation1
Metal bindingi202Magnesium; via carbamate groupUniRule annotation1
Metal bindingi204MagnesiumUniRule annotation1
Metal bindingi205MagnesiumUniRule annotation1
Active sitei294Proton acceptorUniRule annotation1
Binding sitei295SubstrateUniRule annotation1
Binding sitei327SubstrateUniRule annotation1
Sitei334Transition state stabilizerUniRule annotation1
Binding sitei379SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase, Monooxygenase, Oxidoreductase
Biological processCalvin cycle, Carbon dioxide fixation, Photosynthesis
LigandMagnesium, Metal-binding

Enzyme and pathway databases

BioCyciRPAL316057:G1G68-3775-MONOMER

Names & Taxonomyi

Protein namesi
Recommended name:
Ribulose bisphosphate carboxylase large chain 2UniRule annotation (EC:4.1.1.39UniRule annotation)
Short name:
RuBisCO large subunit 2UniRule annotation
Gene namesi
Name:cbbL2UniRule annotation
Ordered Locus Names:RPD_3722
OrganismiRhodopseudomonas palustris (strain BisB5)
Taxonomic identifieri316057 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBradyrhizobiaceaeRhodopseudomonas
Proteomesi
  • UP000001818 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002514591 – 485Ribulose bisphosphate carboxylase large chain 2Add BLAST485

Amino acid modifications

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Modified residuei202N6-carboxylysineUniRule annotation1

Proteomic databases

PRIDEiQ37G91

Interactioni

Subunit structurei

Heterohexadecamer of 8 large chains and 8 small chains.UniRule annotation

Protein-protein interaction databases

STRINGi316057.RPD_3722

Structurei

3D structure databases

ProteinModelPortaliQ37G91
SMRiQ37G91
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RuBisCO large chain family. Type I subfamily.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105DT1 Bacteria
COG1850 LUCA
HOGENOMiHOG000230831
KOiK01601
OMAiHRAMHAA
OrthoDBiPOG091H14UZ

Family and domain databases

CDDicd08212 RuBisCO_large_I, 1 hit
Gene3Di3.20.20.110, 1 hit
3.30.70.150, 1 hit
HAMAPiMF_01338 RuBisCO_L_type1, 1 hit
InterProiView protein in InterPro
IPR033966 RuBisCO
IPR020878 RuBisCo_large_chain_AS
IPR000685 RuBisCO_lsu_C
IPR036376 RuBisCO_lsu_C_sf
IPR017443 RuBisCO_lsu_fd_N
IPR036422 RuBisCO_lsu_N_sf
IPR020888 RuBisCO_lsuI
PfamiView protein in Pfam
PF00016 RuBisCO_large, 1 hit
PF02788 RuBisCO_large_N, 1 hit
SFLDiSFLDS00014 RuBisCO, 1 hit
SUPFAMiSSF51649 SSF51649, 1 hit
SSF54966 SSF54966, 1 hit
PROSITEiView protein in PROSITE
PS00157 RUBISCO_LARGE, 1 hit

Sequencei

Sequence statusi: Complete.

Q37G91-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNDSITVRGK DRYKSGVMEY KKMGYWEPDY VPKDTDVIAL FRVTPQDGVD
60 70 80 90 100
PIEASAAVAG ESSTATWTVV WTDRLTAAEK YRAKCYRVDP VPNSPGQYFA
110 120 130 140 150
YIAYDLDLFE NGSIANLSAS IIGNVFGFKP LKALRLEDMR LPIAYVKTFQ
160 170 180 190 200
GPATGIVVER ERMDKFGRPL LGATVKPKLG LSGRNYGRVV YEALKGGLDF
210 220 230 240 250
TKDDENINSQ PFMHWRERFL YCMEAVNKAQ AASGEIKGTY LNVTAGTMEE
260 270 280 290 300
MYERAEFAKQ LGSVIIMIDL VIGYTAIQSM AKWARRNDMI LHLHRAGHST
310 320 330 340 350
YTRQRNHGVS FRVIAKWMRL AGVDHIHAGT VVGKLEGDPS TTKGYYDICR
360 370 380 390 400
EDYNPANLEH GLFFDQPWAS LNKLMPVASG GIHAGQMHQL LDLLGEDVVL
410 420 430 440 450
QFGGGTIGHP MGIAAGATAN RVALEAMILA RNEGRDYVHE GPEILAKAAQ
460 470 480
TCTPLKAALD TWKNVSFNYE STDTPDYAPT PSVSM
Length:485
Mass (Da):53,733
Last modified:December 6, 2005 - v1
Checksum:i6667A5C476EA33F6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP000283 Genomic DNA Translation: ABE40943.1
RefSeqiWP_011504108.1, NC_007958.1

Genome annotation databases

EnsemblBacteriaiABE40943; ABE40943; RPD_3722
KEGGirpd:RPD_3722

Similar proteinsi

Entry informationi

Entry nameiRBL1B_RHOPS
AccessioniPrimary (citable) accession number: Q37G91
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 3, 2006
Last sequence update: December 6, 2005
Last modified: May 23, 2018
This is version 81 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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