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Q37896 (LYS_BPB03) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Lysozyme

EC=3.2.1.17
Alternative name(s):
Endolysin
Lysis protein
Morphogenesis protein 2
Muramidase
Gene names
Name:15
OrganismBacillus phage B103 (Bacteriophage B103) [Complete proteome]
Taxonomic identifier10778 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stageCaudoviralesPodoviridaePicovirinaePhi29likevirus
Virus hostBacillus subtilis [TaxID: 1423]

Protein attributes

Sequence length263 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Helps to release the mature phage particles from the cell wall by breaking down the peptidoglycan By similarity.

Catalytic activity

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

Domain

LysM repeats are thought to be involved in peptidoglycan binding.

Sequence similarities

Belongs to the glycosyl hydrolase 24 family.

Contains 2 LysM repeats.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 263263Lysozyme
PRO_0000218092

Regions

Repeat165 – 20945LysM 1
Repeat219 – 26345LysM 2

Sites

Active site151Proton donor By similarity

Sequences

Sequence LengthMass (Da)Tools
Q37896 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 5C1A7C8282A1DBCE

FASTA26329,264
        10         20         30         40         50         60 
MNISQAGINL IKSFEGLRTK AYKAVPTEKY YTIGYGHYGS DVHPCQVISE EKAEKLLRDD 

        70         80         90        100        110        120 
VQEFVDGVDK LLKVDVTQSQ FDALVSFAYN VGLGALKSST LLQYLNAGNF QKAANEFLKW 

       130        140        150        160        170        180 
NKSGGKVYNG LVKRREQERT LFLTGESKNV SRETSKPKTS KTNTHVVKKG DTLSEIAKKI 

       190        200        210        220        230        240 
KTSTKTLLEL NPTIKNPNKI YVGQRINVGG SPVKSTLKYK IKRGETLTGI AKKNKTTVSQ 

       250        260 
LMKLNPNIKN ANNIYAGQTI RLK 

« Hide

References

[1]"Bacteriophage B103: complete DNA sequence of its genome and relationship to other Bacillus phages."
Pecenkova T., Benes V., Paces J., Vlcek C., Paces V.
Gene 199:157-163(1997) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X99260 Genomic DNA. Translation: CAA67646.1.
RefSeqNP_690649.1. NC_004165.1.

3D structure databases

ProteinModelPortalQ37896.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyCBM50. Carbohydrate-Binding Module Family 50.
GH24. Glycoside Hydrolase Family 24.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID955364.

Phylogenomic databases

ProtClustDBCLSP2343229.

Family and domain databases

Gene3D1.10.530.40. 1 hit.
3.10.350.10. 2 hits.
InterProIPR002196. Glyco_hydro_24.
IPR018392. LysM_dom.
IPR023346. Lysozyme-like_dom.
IPR023347. Lysozyme_dom.
[Graphical view]
PfamPF01476. LysM. 2 hits.
PF00959. Phage_lysozyme. 1 hit.
[Graphical view]
SMARTSM00257. LysM. 2 hits.
[Graphical view]
SUPFAMSSF53955. SSF53955. 1 hit.
SSF54106. SSF54106. 2 hits.
ProtoNetSearch...

Entry information

Entry nameLYS_BPB03
AccessionPrimary (citable) accession number: Q37896
Entry history
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries