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Q37875 (LYS_BPP1) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 72. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (3) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Lysozyme

EC=3.2.1.17
Alternative name(s):
Endolysin
Lysis protein
Muramidase
Protein gp17
Gene names
Name:17
Synonyms:lysa, lyz
OrganismEnterobacteria phage P1 (Bacteriophage P1) [Reference proteome]
Taxonomic identifier10678 [NCBI]
Taxonomic lineageVirusesdsDNA viruses, no RNA stageCaudoviralesMyoviridaePunalikevirus
Virus hostEnterobacteriaceae [TaxID: 543]

Protein attributes

Sequence length185 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Essential for lysis of bacterial cell wall, by showing cell wall hydrolyzing activity By similarity.

Catalytic activity

Hydrolysis of (1->4)-beta-linkages between N-acetylmuramic acid and N-acetyl-D-glucosamine residues in a peptidoglycan and between N-acetyl-D-glucosamine residues in chitodextrins.

Sequence similarities

Belongs to the glycosyl hydrolase 24 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 185185Lysozyme
PRO_0000218099

Sites

Active site421Proton donor By similarity

Secondary structure

............................... 185
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q37875 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 8F7CA469850049B2

FASTA18520,256
        10         20         30         40         50         60 
MKGKTAAGGG AICAIAVMIT IVMGNGNVRT NQAGLELIGN AEGCRRDPYM CPAGVWTDGI 

        70         80         90        100        110        120 
GNTHGVTPGV RKTDQQIAAD WEKNILIAER CINQHFRGKD MPDNAFSAMT SAAFNMGCNS 

       130        140        150        160        170        180 
LRTYYSKARG MRVETSIHKW AQKGEWVNMC NHLPDFVNSN GVPLRGLKIR REKERQLCLT 


GLVNE 

« Hide

References

« Hide 'large scale' references
[1]"Three functions of bacteriophage P1 involved in cell lysis."
Schmidt C., Velleman M., Arber W.
J. Bacteriol. 178:1099-1104(1996) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[2]Lehnherr H., Bendtsen J.D., Preuss F., Ilyina T.V.
Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
[3]"Genome of bacteriophage P1."
Lobocka M.B., Rose D.J., Plunkett G. III, Rusin M., Samojedny A., Lehnherr H., Yarmolinsky M.B., Blattner F.R.
J. Bacteriol. 186:7032-7068(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
X87673 Genomic DNA. Translation: CAA61013.1.
AF125376 Genomic DNA. Translation: AAD20630.1.
AF234172 Genomic DNA. Translation: AAQ13989.1.
RefSeqYP_006484.1. NC_005856.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1XJTX-ray1.75A1-185[»]
1XJUX-ray1.07A/B29-185[»]
ProteinModelPortalQ37875.
SMRQ37875. Positions 9-185.
ModBaseSearch...
MobiDBSearch...

Protein family/group databases

CAZyGH24. Glycoside Hydrolase Family 24.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2777454.

Family and domain databases

Gene3D1.10.530.40. 1 hit.
InterProIPR002196. Glyco_hydro_24.
IPR023346. Lysozyme-like_dom.
IPR023347. Lysozyme_dom.
[Graphical view]
PfamPF00959. Phage_lysozyme. 1 hit.
[Graphical view]
SUPFAMSSF53955. SSF53955. 1 hit.
ProtoNetSearch...

Other

EvolutionaryTraceQ37875.

Entry information

Entry nameLYS_BPP1
AccessionPrimary (citable) accession number: Q37875
Entry history
Integrated into UniProtKB/Swiss-Prot: December 1, 2000
Last sequence update: November 1, 1996
Last modified: May 14, 2014
This is version 72 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programViral Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

Glycosyl hydrolases

Classification of glycosyl hydrolase families and list of entries