Reviewed, UniProtKB/Swiss-Prot Q37787 (NDUS3_BETVU)

Names and origin

Protein names

Recommended name:
    NADH-ubiquinone oxidoreductase 27 kDa subunit
    EC=1.6.5.3
    EC=1.6.99.3
Alternative name(s):
    Complex I-27kD
      Short name=CI-27kD
    NADH dehydrogenase subunit 9

Gene names

Name:

NAD9

Encoded on

Mitochondrion

Organism

Beta vulgaris (Sugar beet)

Taxonomic identifier

161934 [NCBI]

Taxonomic lineage

Eukaryota › Viridiplantae › Streptophyta › Embryophyta › Tracheophyta › Spermatophyta › Magnoliophyta › eudicotyledons › core eudicotyledons › Caryophyllales › Amaranthaceae › Beta

Protein attributes

Sequence length	192 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at transcript level.

General annotation (Comments)

Function	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity.
Catalytic activity	NADH + ubiquinone = NAD(+) + ubiquinol. NADH + acceptor = NAD(+) + reduced acceptor.
Subunit structure	Complex I is composed of about 30 different subunits.
Subcellular location	Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Sequence similarities	Belongs to the complex I 30 kDa subunit family.
RNA editing	Edited at positions 31, 38, 100, 110 and 123.

Ontologies

Keywords
Biological process	Electron transport Respiratory chain Transport
Cellular component	Membrane Mitochondrion Mitochondrion inner membrane
Coding sequence diversity	RNA editing
Ligand	NAD Ubiquinone
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological process	mitochondrial electron transport, NADH to ubiquinone Inferred from electronic annotation. Source: InterPro transport Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	mitochondrial respiratory chain Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	NADH dehydrogenase (ubiquinone) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 192	192	NADH-ubiquinone oxidoreductase 27 kDa subunit		PRO_0000118639

Sequences

	Sequence		Length	Mass (Da)
	Q37787-1 [UniParc]. Last modified October 24, 2003. Version 3. Checksum: 6D111D64E4C71CCE	FASTA	192	23,151
	10 20 30 40 50 60 MDNQFIFKYS WETLPKKWVK KIEKSEHGNR FDTNTDYLFQ LLCFLKLHTY TRFQVLIDIC 70 80 90 100 110 120 GVDYPSRKRR FEVVYNLLST RYNSRIRLQT CADEVTRISL VVSLFPSAGW WEREVWDMFG 130 140 150 160 170 180 VSFINHPDLR RILTDYGFEG HPLRKDFPLS GYVEVRYDDP EKRVVSEPIE MTQEFRYFDF 190 ASPWEQRNGN EG

References

[1]

"The sugar beet mitochondrial genome contains an ORF sharing sequence homology with the gene for the 30 kDa subunit of bovine mitochondrial complex I." Kubo T., Mikami T., Kinoshita T. Mol. Gen. Genet. 241:479-481(1993) [PubMed: 8246903] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA], RNA EDITING. Strain: cv. TK81-O. Tissue: Tap root.

Cross-references

Sequence databases
EMBLGenBankDDBJ	D38016 Genomic DNA. Translation: BAA07213.2.
PIR	S62130.
3D structure databases
ModBase	Search...
Family and domain databases
InterPro	IPR010218. NADH_DH_csu. IPR001268. NADH_DHase_Ub_30kDa_su. [Graphical view]
Pfam	PF00329. Complex1_30kDa. 1 hit. [Graphical view]
ProDom	PD001581. Complex1_30K. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR01961. NuoC_fam. 1 hit.
PROSITE	PS00542. COMPLEX1_30K. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NDUS3_BETVU

Accession

Primary (citable) accession number: Q37787

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 1, 1997
Last sequence update:	October 24, 2003
Last modified:	November 25, 2008
This is version 54 of the entry and version 3 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

PPAP (Plant Proteome Annotation Project)