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Protein

Phosphoglycerate kinase

Gene

p56

Organism
Trypanosoma brucei
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei312ATPUniRule annotation1
Binding sitei434ATPUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotation, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoglycerate kinaseUniRule annotation (EC:2.7.2.3UniRule annotation)
Gene namesi
Name:p56Imported
Encoded oniMitochondrionImported
OrganismiTrypanosoma bruceiImported
Taxonomic identifieri5691 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaTrypanosomatidaeTrypanosoma

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

MitochondrionImported

PTM / Processingi

Proteomic databases

PaxDbiQ37743.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi5691.CAJ15981.

Structurei

3D structure databases

ProteinModelPortaliQ37743.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the phosphoglycerate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1367. Eukaryota.
COG0126. LUCA.

Family and domain databases

CDDicd00318. Phosphoglycerate_kinase. 1 hit.
Gene3Di3.40.50.1260. 2 hits.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase. 1 hit.
InterProiIPR027250. Pgk_euglenozoa.
IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 2 hits.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PIRSF500126. Pgk_euglenozoa. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 2 hits.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q37743-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSTAPNAKNN ISLKKSVGDV WPLTGKRVLM RVDFNVPMQN GHITNDYRIR
60 70 80 90 100
AAIPTIRRVI DQGGICILLS HLGRPRGVSM VAGVRDIRRR YHEAQFHDNK
110 120 130 140 150
GKTAFFSVLP GEEKVKILAK SSAREEATHI SPEVKSGKTM LFARLPEDEK
160 170 180 190 200
KSLLMQYLNE NKDSALPQMS VSAGYEEQYR SRPVAVRLAE LLGQHVYFAH
210 220 230 240 250
DCLDARVEVS RLKRGNVMLL ENVRFYSEEN GENAEEREAM AKILASYGDV
260 270 280 290 300
YISDAFGAAH RDSATMTGIP KILGHGAAGY LMEKEISYFA KVLGNPPRPL
310 320 330 340 350
VAIVGGAKVS EKIQLLDNML QRIDYLLIGG AMAYTFLKAQ GYSIGISKCE
360 370 380 390 400
ESKLEFARSL LKKAEDRKVQ VILPIDHVCH TEFKAVDSPL ITEDQNIPEG
410 420 430 440 450
HMALDIGPKT IEKYVQTIGK CKSAIWNGPM GVFEMVPYSK GTFAIAKAMG
460 470 480 490 500
RGTQKRGLMS IIGGGESAGA AELCGEAARI SHVSTGGGAS LELLEGKTLP

GVAVLDDKE
Length:509
Mass (Da):55,747
Last modified:November 1, 1996 - v1
Checksum:i8F5CD49EAC57D75A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M37784 Genomic DNA. Translation: AAA32119.1.
PIRiA45593.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
M37784 Genomic DNA. Translation: AAA32119.1.
PIRiA45593.

3D structure databases

ProteinModelPortaliQ37743.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi5691.CAJ15981.

Proteomic databases

PaxDbiQ37743.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Phylogenomic databases

eggNOGiKOG1367. Eukaryota.
COG0126. LUCA.

Family and domain databases

CDDicd00318. Phosphoglycerate_kinase. 1 hit.
Gene3Di3.40.50.1260. 2 hits.
3.40.50.1270. 1 hit.
HAMAPiMF_00145. Phosphoglyc_kinase. 1 hit.
InterProiIPR027250. Pgk_euglenozoa.
IPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERiPTHR11406. PTHR11406. 2 hits.
PfamiPF00162. PGK. 1 hit.
[Graphical view]
PIRSFiPIRSF000724. Pgk. 1 hit.
PIRSF500126. Pgk_euglenozoa. 1 hit.
PRINTSiPR00477. PHGLYCKINASE.
SUPFAMiSSF53748. SSF53748. 2 hits.
PROSITEiPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ37743_9TRYP
AccessioniPrimary (citable) accession number: Q37743
Entry historyi
Integrated into UniProtKB/TrEMBL: November 1, 1996
Last sequence update: November 1, 1996
Last modified: October 5, 2016
This is version 80 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.