UniProtKB - Q37743 (Q37743_9TRYP)
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Protein
Phosphoglycerate kinase
Gene
p56
Organism
Trypanosoma brucei
Status
Functioni
Catalytic activityi
ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate.UniRule annotation
: glycolysis Pathwayi
This protein is involved in step 2 of the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate.UniRule annotationProteins known to be involved in the 5 steps of the subpathway in this organism are:
- no protein annotated in this organism
- Phosphoglycerate kinase (p56), Phosphoglycerate kinase, Phosphoglycerate kinase (cPGK-8)
- no protein annotated in this organism
- no protein annotated in this organism
- no protein annotated in this organism
View all proteins of this organism that are known to be involved in the subpathway that synthesizes pyruvate from D-glyceraldehyde 3-phosphate, the pathway glycolysis and in Carbohydrate degradation.
GO - Molecular functioni
- phosphoglycerate kinase activity Source: UniProtKB-EC
GO - Biological processi
- glycolytic process Source: UniProtKB-UniPathway
Keywordsi
Molecular function | KinaseUniRule annotation, Transferase |
Enzyme and pathway databases
UniPathwayi | UPA00109; UER00185. |
Names & Taxonomyi
Protein namesi | |
Gene namesi | Name:p56Imported |
Encoded oni | MitochondrionImported |
Organismi | Trypanosoma bruceiImported |
Taxonomic identifieri | 5691 [NCBI] |
Taxonomic lineagei | Eukaryota › Euglenozoa › Kinetoplastida › Trypanosomatidae › Trypanosoma › |
Subcellular locationi
GO - Cellular componenti
- mitochondrion Source: UniProtKB-KW
Keywords - Cellular componenti
MitochondrionImportedInteractioni
Subunit structurei
Monomer.UniRule annotation
Family & Domainsi
Coiled coil
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Coiled coili | 347 – 367 | Sequence analysisAdd BLAST | 21 |
Sequence similaritiesi
Belongs to the phosphoglycerate kinase family.UniRule annotation
Keywords - Domaini
Coiled coilSequence analysisPhylogenomic databases
eggNOGi | KOG1367. Eukaryota. COG0126. LUCA. |
Family and domain databases
CDDi | cd00318. Phosphoglycerate_kinase. 1 hit. |
Gene3Di | 3.40.50.1260. 3 hits. |
HAMAPi | MF_00145. Phosphoglyc_kinase. 1 hit. |
InterProi | View protein in InterPro IPR001576. Phosphoglycerate_kinase. IPR015911. Phosphoglycerate_kinase_CS. IPR015824. Phosphoglycerate_kinase_N. IPR036043. Phosphoglycerate_kinase_sf. |
PANTHERi | PTHR11406. PTHR11406. 1 hit. |
Pfami | View protein in Pfam PF00162. PGK. 1 hit. |
PRINTSi | PR00477. PHGLYCKINASE. |
SUPFAMi | SSF53748. SSF53748. 2 hits. |
PROSITEi | View protein in PROSITE PS00111. PGLYCERATE_KINASE. 1 hit. |
i Sequence
Sequence statusi: Complete.
Q37743-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MSTAPNAKNN ISLKKSVGDV WPLTGKRVLM RVDFNVPMQN GHITNDYRIR
60 70 80 90 100
AAIPTIRRVI DQGGICILLS HLGRPRGVSM VAGVRDIRRR YHEAQFHDNK
110 120 130 140 150
GKTAFFSVLP GEEKVKILAK SSAREEATHI SPEVKSGKTM LFARLPEDEK
160 170 180 190 200
KSLLMQYLNE NKDSALPQMS VSAGYEEQYR SRPVAVRLAE LLGQHVYFAH
210 220 230 240 250
DCLDARVEVS RLKRGNVMLL ENVRFYSEEN GENAEEREAM AKILASYGDV
260 270 280 290 300
YISDAFGAAH RDSATMTGIP KILGHGAAGY LMEKEISYFA KVLGNPPRPL
310 320 330 340 350
VAIVGGAKVS EKIQLLDNML QRIDYLLIGG AMAYTFLKAQ GYSIGISKCE
360 370 380 390 400
ESKLEFARSL LKKAEDRKVQ VILPIDHVCH TEFKAVDSPL ITEDQNIPEG
410 420 430 440 450
HMALDIGPKT IEKYVQTIGK CKSAIWNGPM GVFEMVPYSK GTFAIAKAMG
460 470 480 490 500
RGTQKRGLMS IIGGGESAGA AELCGEAARI SHVSTGGGAS LELLEGKTLP
GVAVLDDKE
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | M37784 Genomic DNA. Translation: AAA32119.1. |
PIRi | A45593. |
Similar proteinsi
Entry informationi
Entry namei | Q37743_9TRYP | |
Accessioni | Q37743Primary (citable) accession number: Q37743 | |
Entry historyi | Integrated into UniProtKB/TrEMBL: | November 1, 1996 |
Last sequence update: | November 1, 1996 | |
Last modified: | February 28, 2018 | |
This is version 90 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Unreviewed (UniProtKB/TrEMBL) |