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Q37720

- NDUS2_PYLLI

UniProt

Q37720 - NDUS2_PYLLI

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Protein

NADH-ubiquinone oxidoreductase 49 kDa subunit

Gene
NAD7
Organism
Pylaiella littoralis
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity. Component of the iron-sulfur (IP) fragment of the enzyme. Component of the iron-sulfur (IP) fragment of the enzyme.UniRule annotation

Catalytic activityi

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).UniRule annotation
NADH + acceptor = NAD+ + reduced acceptor.UniRule annotation

GO - Molecular functioni

  1. NAD binding Source: InterPro
  2. NADH dehydrogenase (ubiquinone) activity Source: UniProtKB-EC
  3. quinone binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Keywords - Ligandi

NAD, Ubiquinone

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-ubiquinone oxidoreductase 49 kDa subunit (EC:1.6.5.3, EC:1.6.99.3)
Alternative name(s):
NADH dehydrogenase subunit 7
Gene namesi
Name:NAD7
Encoded oniMitochondrion
OrganismiPylaiella littoralis
Taxonomic identifieri2885 [NCBI]
Taxonomic lineageiEukaryotaStramenopilesPX cladePhaeophyceaeEctocarpalesAcinetosporaceaePylaiella

Subcellular locationi

GO - Cellular componenti

  1. mitochondrion Source: UniProtKB-SubCell
  2. respiratory chain Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 398398NADH-ubiquinone oxidoreductase 49 kDa subunitUniRule annotationPRO_0000118592Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ37720.

Family & Domainsi

Sequence similaritiesi

Family and domain databases

Gene3Di1.10.645.10. 2 hits.
HAMAPiMF_01358. NDH1_NuoD.
InterProiIPR001135. NADH_Q_OxRdtase_suD.
IPR014029. NADH_UbQ_OxRdtase_49kDa_CS.
IPR022885. NDH1_su_D/H.
IPR029014. NiFe_Hase-like.
[Graphical view]
PfamiPF00346. Complex1_49kDa. 1 hit.
[Graphical view]
SUPFAMiSSF56762. SSF56762. 1 hit.
TIGRFAMsiTIGR01962. NuoD. 1 hit.
PROSITEiPS00535. COMPLEX1_49K. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q37720-1 [UniParc]FASTAAdd to Basket

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MALKKKEFNK KLKHFTINFG PQHPAAHGVL RLILELNGEV VQRADPHIGL    50
LHRGTEKLIE AKTYFQALPY FDRLDYVSMM CQEHTYALSV ENLLQVSIPR 100
RAQFIRVLFA EITRILNHLL AVGCHAMDVG AMTPFLWAFE EREKLMEFYE 150
RVSGARMHAS YFRPGGVSQD ISVGLVDDIF AFVAQFGQRL DEIEEMLTDN 200
RIWQERLVDI GVVSAQEAID WGFSGVMLRG SGIRWDLRKN EPYEIYSDLN 250
FQGVVGKTGD CYDRYLARVE EMRQSLSIIY QCLNKMPRGS VKIDDAKISP 300
PSRSEVKQSM ESLIHHFKLY TEGVFVPAGE TYTATEAPKG EFGVYLVSKG 350
SSRPYRCKIK APGFSHLQGL NFMACSHMLA DVVTIIGTQD IVFGEVDR 398
Length:398
Mass (Da):45,245
Last modified:November 1, 1996 - v1
Checksum:iD3C46D2B7CA33FF6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z48623 Genomic DNA. Translation: CAA88557.1.
PIRiS53054.
RefSeqiNP_150429.1. NC_003055.1.

Genome annotation databases

GeneIDi803753.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z48623 Genomic DNA. Translation: CAA88557.1 .
PIRi S53054.
RefSeqi NP_150429.1. NC_003055.1.

3D structure databases

ProteinModelPortali Q37720.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 803753.

Family and domain databases

Gene3Di 1.10.645.10. 2 hits.
HAMAPi MF_01358. NDH1_NuoD.
InterProi IPR001135. NADH_Q_OxRdtase_suD.
IPR014029. NADH_UbQ_OxRdtase_49kDa_CS.
IPR022885. NDH1_su_D/H.
IPR029014. NiFe_Hase-like.
[Graphical view ]
Pfami PF00346. Complex1_49kDa. 1 hit.
[Graphical view ]
SUPFAMi SSF56762. SSF56762. 1 hit.
TIGRFAMsi TIGR01962. NuoD. 1 hit.
PROSITEi PS00535. COMPLEX1_49K. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Characterisation of the cox3, nad7 and atp6 genes from the mitochondrial genome of the brown alga Pylaiella littoralis."
    Fontaine J.-M., Rousvoal S., Delaroque N., Loiseaux-De Goer S.
    Plant Physiol. Biochem. 33:605-609(1995)
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiNDUS2_PYLLI
AccessioniPrimary (citable) accession number: Q37720
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: June 11, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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