Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q37720

- NDUS2_PYLLI

UniProt

Q37720 - NDUS2_PYLLI

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

NADH-ubiquinone oxidoreductase 49 kDa subunit

Gene

NAD7

Organism
Pylaiella littoralis
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity). Component of the iron-sulfur (IP) fragment of the enzyme. Component of the iron-sulfur (IP) fragment of the enzyme.By similarity

Catalytic activityi

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).
NADH + acceptor = NAD+ + reduced acceptor.

GO - Molecular functioni

  1. NAD binding Source: InterPro
  2. NADH dehydrogenase (ubiquinone) activity Source: UniProtKB-EC
  3. quinone binding Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Keywords - Ligandi

NAD, Ubiquinone

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-ubiquinone oxidoreductase 49 kDa subunit (EC:1.6.5.3, EC:1.6.99.3)
Alternative name(s):
NADH dehydrogenase subunit 7
Gene namesi
Name:NAD7
Encoded oniMitochondrion
OrganismiPylaiella littoralis
Taxonomic identifieri2885 [NCBI]
Taxonomic lineageiEukaryotaStramenopilesPX cladePhaeophyceaeEctocarpalesAcinetosporaceaePylaiella

Subcellular locationi

GO - Cellular componenti

  1. mitochondrion Source: UniProtKB-KW
  2. respiratory chain Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 398398NADH-ubiquinone oxidoreductase 49 kDa subunitPRO_0000118592Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ37720.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I 49 kDa subunit family.Curated

Family and domain databases

Gene3Di1.10.645.10. 2 hits.
HAMAPiMF_01358. NDH1_NuoD.
InterProiIPR001135. NADH_Q_OxRdtase_suD.
IPR014029. NADH_UbQ_OxRdtase_49kDa_CS.
IPR022885. NDH1_su_D/H.
IPR029014. NiFe_Hase-like.
[Graphical view]
PfamiPF00346. Complex1_49kDa. 1 hit.
[Graphical view]
SUPFAMiSSF56762. SSF56762. 1 hit.
TIGRFAMsiTIGR01962. NuoD. 1 hit.
PROSITEiPS00535. COMPLEX1_49K. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q37720-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MALKKKEFNK KLKHFTINFG PQHPAAHGVL RLILELNGEV VQRADPHIGL
60 70 80 90 100
LHRGTEKLIE AKTYFQALPY FDRLDYVSMM CQEHTYALSV ENLLQVSIPR
110 120 130 140 150
RAQFIRVLFA EITRILNHLL AVGCHAMDVG AMTPFLWAFE EREKLMEFYE
160 170 180 190 200
RVSGARMHAS YFRPGGVSQD ISVGLVDDIF AFVAQFGQRL DEIEEMLTDN
210 220 230 240 250
RIWQERLVDI GVVSAQEAID WGFSGVMLRG SGIRWDLRKN EPYEIYSDLN
260 270 280 290 300
FQGVVGKTGD CYDRYLARVE EMRQSLSIIY QCLNKMPRGS VKIDDAKISP
310 320 330 340 350
PSRSEVKQSM ESLIHHFKLY TEGVFVPAGE TYTATEAPKG EFGVYLVSKG
360 370 380 390
SSRPYRCKIK APGFSHLQGL NFMACSHMLA DVVTIIGTQD IVFGEVDR
Length:398
Mass (Da):45,245
Last modified:November 1, 1996 - v1
Checksum:iD3C46D2B7CA33FF6
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z48623 Genomic DNA. Translation: CAA88557.1.
PIRiS53054.
RefSeqiNP_150429.1. NC_003055.1.

Genome annotation databases

GeneIDi803753.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
Z48623 Genomic DNA. Translation: CAA88557.1 .
PIRi S53054.
RefSeqi NP_150429.1. NC_003055.1.

3D structure databases

ProteinModelPortali Q37720.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 803753.

Family and domain databases

Gene3Di 1.10.645.10. 2 hits.
HAMAPi MF_01358. NDH1_NuoD.
InterProi IPR001135. NADH_Q_OxRdtase_suD.
IPR014029. NADH_UbQ_OxRdtase_49kDa_CS.
IPR022885. NDH1_su_D/H.
IPR029014. NiFe_Hase-like.
[Graphical view ]
Pfami PF00346. Complex1_49kDa. 1 hit.
[Graphical view ]
SUPFAMi SSF56762. SSF56762. 1 hit.
TIGRFAMsi TIGR01962. NuoD. 1 hit.
PROSITEi PS00535. COMPLEX1_49K. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Characterisation of the cox3, nad7 and atp6 genes from the mitochondrial genome of the brown alga Pylaiella littoralis."
    Fontaine J.-M., Rousvoal S., Delaroque N., Loiseaux-De Goer S.
    Plant Physiol. Biochem. 33:605-609(1995)
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].

Entry informationi

Entry nameiNDUS2_PYLLI
AccessioniPrimary (citable) accession number: Q37720
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3