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Protein

Cytochrome c oxidase subunit 3

Gene

MT-CO3

Organism
Theileria annulata
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:MT-CO3
Synonyms:COIII, COXIII, MTCO3
ORF Names:Tap370b08.q2ca38.02c
Encoded oniMitochondrion
OrganismiTheileria annulata
Taxonomic identifieri5874 [NCBI]
Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaPiroplasmidaTheileriidaeTheileria
Proteomesi
  • UP000001950 Componenti: Mitochondrion

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei12 – 29HelicalSequence analysisAdd BLAST18
Transmembranei57 – 77HelicalSequence analysisAdd BLAST21
Transmembranei91 – 111HelicalSequence analysisAdd BLAST21
Transmembranei126 – 146HelicalSequence analysisAdd BLAST21
Transmembranei155 – 175HelicalSequence analysisAdd BLAST21
Transmembranei196 – 216HelicalSequence analysisAdd BLAST21
Transmembranei235 – 255HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001838621 – 255Cytochrome c oxidase subunit 3Add BLAST255

Structurei

3D structure databases

ProteinModelPortaliQ37679.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

InParanoidiQ37679.

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase-like_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q37679-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRNSVQSDLK YINIINISET LYLFYSTGLD TLEYIDSTYK NFIIMYVNQH
60 70 80 90 100
LLYGTTLKYL SVGEFFINSL TIFINGIRET MTSSTVIMYA IFGMFIFSEI
110 120 130 140 150
MVFSTFIWGF FHFRLSNPVM IIEVNLEAFL QISDVLNAGS ILISLILQRI
160 170 180 190 200
EERGYFEVDY MLERLILIGF IFLSFQGDEY SLVKSYINNH WVTLYFNVLT
210 220 230 240 250
GLHSLHVYVG GIFALMQAFA SENCGCQKDE DFNAGMYWHF VEIIWIALTM

LLFLL
Length:255
Mass (Da):29,717
Last modified:November 1, 1996 - v1
Checksum:i1C42F4BC0A6F1336
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U32225 Genomic DNA. Translation: AAA73631.1.
CR940346 Genomic DNA. Translation: CAI72675.1.

Genome annotation databases

EnsemblProtistsiCAI72675; CAI72675; Tap370b08.q2ca38.02c.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U32225 Genomic DNA. Translation: AAA73631.1.
CR940346 Genomic DNA. Translation: CAI72675.1.

3D structure databases

ProteinModelPortaliQ37679.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblProtistsiCAI72675; CAI72675; Tap370b08.q2ca38.02c.

Phylogenomic databases

InParanoidiQ37679.

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase-like_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERiPTHR11403. PTHR11403. 1 hit.
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiCOX3_THEAN
AccessioniPrimary (citable) accession number: Q37679
Secondary accession number(s): Q4UJ68
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: November 30, 2016
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.