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Q37679 (COX3_THEAN) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 81. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:MT-CO3
Synonyms:COIII, COXIII, MTCO3
ORF Names:Tap370b08.q2ca38.02c
Encoded onMitochondrion
OrganismTheileria annulata [Reference proteome]
Taxonomic identifier5874 [NCBI]
Taxonomic lineageEukaryotaAlveolataApicomplexaAconoidasidaPiroplasmidaTheileriidaeTheileria

Protein attributes

Sequence length255 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 255255Cytochrome c oxidase subunit 3
PRO_0000183862

Regions

Transmembrane12 – 2918Helical; Potential
Transmembrane57 – 7721Helical; Potential
Transmembrane91 – 11121Helical; Potential
Transmembrane126 – 14621Helical; Potential
Transmembrane155 – 17521Helical; Potential
Transmembrane196 – 21621Helical; Potential
Transmembrane235 – 25521Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q37679 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 1C42F4BC0A6F1336

FASTA25529,717
        10         20         30         40         50         60 
MRNSVQSDLK YINIINISET LYLFYSTGLD TLEYIDSTYK NFIIMYVNQH LLYGTTLKYL 

        70         80         90        100        110        120 
SVGEFFINSL TIFINGIRET MTSSTVIMYA IFGMFIFSEI MVFSTFIWGF FHFRLSNPVM 

       130        140        150        160        170        180 
IIEVNLEAFL QISDVLNAGS ILISLILQRI EERGYFEVDY MLERLILIGF IFLSFQGDEY 

       190        200        210        220        230        240 
SLVKSYINNH WVTLYFNVLT GLHSLHVYVG GIFALMQAFA SENCGCQKDE DFNAGMYWHF 

       250 
VEIIWIALTM LLFLL 

« Hide

References

« Hide 'large scale' references
[1]"Synonymous codon usage (SCU) bias differentiates Theilerial nuclear genes from mitochondrial ones."
Lawson D., Hall R.
Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: Hissar.
[2]"Genome of the host-cell transforming parasite Theileria annulata compared with T. parva."
Pain A., Renauld H., Berriman M., Murphy L., Yeats C.A., Weir W., Kerhornou A., Aslett M., Bishop R., Bouchier C., Cochet M., Coulson R.M.R., Cronin A., de Villiers E.P., Fraser A., Fosker N., Gardner M., Goble A. expand/collapse author list , Griffiths-Jones S., Harris D.E., Katzer F., Larke N., Lord A., Maser P., McKellar S., Mooney P., Morton F., Nene V., O'Neil S., Price C., Quail M.A., Rabbinowitsch E., Rawlings N.D., Rutter S., Saunders D., Seeger K., Shah T., Squares R., Squares S., Tivey A., Walker A.R., Woodward J., Dobbelaere D.A.E., Langsley G., Rajandream M.A., McKeever D., Shiels B., Tait A., Barrell B.G., Hall N.
Science 309:131-133(2005) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Ankara.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U32225 Genomic DNA. Translation: AAA73631.1.
CR940346 Genomic DNA. Translation: CAI72675.1.
RefSeqXP_954717.1. XM_949624.1.

3D structure databases

ProteinModelPortalQ37679.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING5874.Q37679.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID3864553.
KEGGtan:q2ca38.02c.

Organism-specific databases

EuPathDBPiroplasmaDB:Tap370b08.q2ca38.02c.

Phylogenomic databases

eggNOGCOG1845.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_THEAN
AccessionPrimary (citable) accession number: Q37679
Secondary accession number(s): Q4UJ68
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 81 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families