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Q37679

- COX3_THEAN

UniProt

Q37679 - COX3_THEAN

Protein

Cytochrome c oxidase subunit 3

Gene

MT-CO3

Organism
Theileria annulata
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 83 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Subunits I, II and III form the functional core of the enzyme complex.

    Catalytic activityi

    4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

    GO - Molecular functioni

    1. cytochrome-c oxidase activity Source: UniProtKB-EC

    GO - Biological processi

    1. respiratory electron transport chain Source: InterPro

    Keywords - Molecular functioni

    Oxidoreductase

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
    Alternative name(s):
    Cytochrome c oxidase polypeptide III
    Gene namesi
    Name:MT-CO3
    Synonyms:COIII, COXIII, MTCO3
    ORF Names:Tap370b08.q2ca38.02c
    Encoded oniMitochondrion
    OrganismiTheileria annulata
    Taxonomic identifieri5874 [NCBI]
    Taxonomic lineageiEukaryotaAlveolataApicomplexaAconoidasidaPiroplasmidaTheileriidaeTheileria
    ProteomesiUP000001950: Mitochondrion

    Organism-specific databases

    EuPathDBiPiroplasmaDB:Tap370b08.q2ca38.02c.

    Subcellular locationi

    GO - Cellular componenti

    1. integral component of membrane Source: UniProtKB-KW
    2. mitochondrial inner membrane Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 255255Cytochrome c oxidase subunit 3PRO_0000183862Add
    BLAST

    Interactioni

    Protein-protein interaction databases

    STRINGi5874.Q37679.

    Structurei

    3D structure databases

    ProteinModelPortaliQ37679.
    ModBaseiSearch...
    MobiDBiSearch...

    Transmembrane

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Transmembranei12 – 2918HelicalSequence AnalysisAdd
    BLAST
    Transmembranei57 – 7721HelicalSequence AnalysisAdd
    BLAST
    Transmembranei91 – 11121HelicalSequence AnalysisAdd
    BLAST
    Transmembranei126 – 14621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei155 – 17521HelicalSequence AnalysisAdd
    BLAST
    Transmembranei196 – 21621HelicalSequence AnalysisAdd
    BLAST
    Transmembranei235 – 25521HelicalSequence AnalysisAdd
    BLAST

    Family & Domainsi

    Sequence similaritiesi

    Keywords - Domaini

    Transmembrane, Transmembrane helix

    Phylogenomic databases

    eggNOGiCOG1845.

    Family and domain databases

    Gene3Di1.20.120.80. 1 hit.
    InterProiIPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view]
    PfamiPF00510. COX3. 1 hit.
    [Graphical view]
    SUPFAMiSSF81452. SSF81452. 1 hit.
    PROSITEiPS50253. COX3. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q37679-1 [UniParc]FASTAAdd to Basket

    « Hide

    MRNSVQSDLK YINIINISET LYLFYSTGLD TLEYIDSTYK NFIIMYVNQH    50
    LLYGTTLKYL SVGEFFINSL TIFINGIRET MTSSTVIMYA IFGMFIFSEI 100
    MVFSTFIWGF FHFRLSNPVM IIEVNLEAFL QISDVLNAGS ILISLILQRI 150
    EERGYFEVDY MLERLILIGF IFLSFQGDEY SLVKSYINNH WVTLYFNVLT 200
    GLHSLHVYVG GIFALMQAFA SENCGCQKDE DFNAGMYWHF VEIIWIALTM 250
    LLFLL 255
    Length:255
    Mass (Da):29,717
    Last modified:November 1, 1996 - v1
    Checksum:i1C42F4BC0A6F1336
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U32225 Genomic DNA. Translation: AAA73631.1.
    CR940346 Genomic DNA. Translation: CAI72675.1.

    Genome annotation databases

    KEGGitan:q2ca38.02c.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U32225 Genomic DNA. Translation: AAA73631.1 .
    CR940346 Genomic DNA. Translation: CAI72675.1 .

    3D structure databases

    ProteinModelPortali Q37679.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 5874.Q37679.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    KEGGi tan:q2ca38.02c.

    Organism-specific databases

    EuPathDBi PiroplasmaDB:Tap370b08.q2ca38.02c.

    Phylogenomic databases

    eggNOGi COG1845.

    Family and domain databases

    Gene3Di 1.20.120.80. 1 hit.
    InterProi IPR013833. Cyt_c_oxidase_su3_a-hlx.
    IPR000298. Cyt_c_oxidase_su3_dom.
    [Graphical view ]
    Pfami PF00510. COX3. 1 hit.
    [Graphical view ]
    SUPFAMi SSF81452. SSF81452. 1 hit.
    PROSITEi PS50253. COX3. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Synonymous codon usage (SCU) bias differentiates Theilerial nuclear genes from mitochondrial ones."
      Lawson D., Hall R.
      Submitted (JUL-1995) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: Hissar.
    2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Ankara.

    Entry informationi

    Entry nameiCOX3_THEAN
    AccessioniPrimary (citable) accession number: Q37679
    Secondary accession number(s): Q4UJ68
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: July 15, 1998
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 83 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3