Q37622 (NDUS3_PROWI) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
NADH-ubiquinone oxidoreductase subunit 9
EC=1.6.5.3
EC=1.6.99.3

Gene names

Name:

NAD9

Encoded on

Mitochondrion

Organism

Prototheca wickerhamii

Taxonomic identifier

3111 [NCBI]

Taxonomic lineage

cellular organisms › Eukaryota › Viridiplantae › Chlorophyta › Trebouxiophyceae › Chlorellales › Chlorellaceae › Prototheca

Protein attributes

Sequence length	192 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity.
Catalytic activity	NADH + ubiquinone = NAD+ + ubiquinol. NADH + acceptor = NAD+ + reduced acceptor.
Subunit structure	Complex I is composed of about 30 different subunits.
Subcellular location	Mitochondrion inner membrane By similarity. Note: Matrix and cytoplasmic side of the mitochondrial inner membrane By similarity.
Sequence similarities	Belongs to the complex I 30 kDa subunit family.

Ontologies

Keywords
Biological process	Electron transport Respiratory chain Transport
Cellular component	Membrane Mitochondrion Mitochondrion inner membrane
Ligand	NAD Ubiquinone
Molecular function	Oxidoreductase
Gene Ontology (GO)
Biological_process	electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW
Cellular_component	mitochondrial inner membrane Inferred from electronic annotation. Source: UniProtKB-SubCell respiratory chain Inferred from electronic annotation. Source: UniProtKB-KW
Molecular_function	NADH dehydrogenase (ubiquinone) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 192	192	NADH-ubiquinone oxidoreductase subunit 9		PRO_0000118648

Sequences

	Sequence		Length	Mass (Da)
	Q37622 [UniParc]. Last modified November 1, 1996. Version 1. Checksum: F04204944207582D	FASTA	192	23,204
	10 20 30 40 50 60 MNNNFEKSIL LMVPQWIQYH VSHRNETTFY VYPEYLKPFL YFLRDHMSTQ YKVCIDITAA 70 80 90 100 110 120 DYPSRASRFE CVYNLLSVEY NSRIRIKTCV DEITTLESVT PVYSSAAWWE REVWDMFGVF 130 140 150 160 170 180 FHNHPDLRRI LTDYGFQGHP LRKDFPLSGY VEVRYDDSEK RVCIESVEYS QEFRYFDFES 190 PWEQVDKNSL LK

References

[1]

"Complete sequence of the mitochondrial DNA of the chlorophyte alga Prototheca wickerhamii. Gene content and genome organization." Wolff G., Plante I., Lang B.F., Kueck U., Burger G. J. Mol. Biol. 237:75-86(1994) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 263-11.

Cross-references

Sequence databases
EMBL GenBank DDBJ	U02970 Genomic DNA. Translation: AAD12649.1.
PIR	T11930.
RefSeq	NP_042261.1. NC_001613.1.
3D structure databases
ProteinModelPortal	Q37622.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	802143.
Family and domain databases
InterPro	IPR010218. NADH_DH_suC. IPR001268. NADH_UbQ_OxRdtase_30kDa_su. IPR020396. NADH_UbQ_OxRdtase_CS. [Graphical view]
Pfam	PF00329. Complex1_30kDa. 1 hit. [Graphical view]
ProDom	PD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit. [Graphical view] [Entries sharing at least one domain]
TIGRFAMs	TIGR01961. NuoC_fam. 1 hit.
PROSITE	PS00542. COMPLEX1_30K. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

NDUS3_PROWI

Accession

Primary (citable) accession number: Q37622

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 30, 2000
Last sequence update:	November 1, 1996
Last modified:	April 3, 2013
This is version 66 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Plant Protein Annotation Program