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Q37620 (COX3_PROWI) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 71. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COX3
Encoded onMitochondrion
OrganismPrototheca wickerhamii
Taxonomic identifier3111 [NCBI]
Taxonomic lineageEukaryotaViridiplantaeChlorophytaTrebouxiophyceaeChlorellalesChlorellaceaePrototheca

Protein attributes

Sequence length262 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 262262Cytochrome c oxidase subunit 3
PRO_0000183839

Regions

Transmembrane13 – 3321Helical; Potential
Transmembrane38 – 5821Helical; Potential
Transmembrane82 – 10221Helical; Potential
Transmembrane134 – 15421Helical; Potential
Transmembrane159 – 17921Helical; Potential
Transmembrane200 – 22021Helical; Potential
Transmembrane237 – 25721Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q37620 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: F4CC81AB17C2850E

FASTA26229,600
        10         20         30         40         50         60 
MRKHPFHLVD PSPWPLLASF AAFLSTTGGV MYMHAYSGGG LLLAIGQLSL FYVMYVWWRD 

        70         80         90        100        110        120 
VIREGTYQGH HTNPVQVGLR YGMLLFILSE IMFFFAFFWA FFHSSLAPTI EIGAVWPPKG 

       130        140        150        160        170        180 
IQVLNPWEIP FLNTIILLTS GASVTWAHHA ILAGNRKQGI ISLAITVLLA VIFTGFQALE 

       190        200        210        220        230        240 
YLEAPFTISD GIYGSTFYLA TGFHGFHVII GTIFIAVCLF RLVLHHFSKS HHLGFEAAAW 

       250        260 
YWHMVDVVWL FLFVCIYYWG GA 

« Hide

References

[1]"Complete sequence of the mitochondrial DNA of the chlorophyte alga Prototheca wickerhamii. Gene content and genome organization."
Wolff G., Plante I., Lang B.F., Kueck U., Burger G.
J. Mol. Biol. 237:75-86(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: 263-11.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U02970 Genomic DNA. Translation: AAD12641.1.
PIRT11922.
RefSeqNP_042253.1. NC_001613.1.

3D structure databases

ProteinModelPortalQ37620.
SMRQ37620. Positions 2-260.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID802127.

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR024791. Cyt_c/ubiquinol_Oxase_su3.
IPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PANTHERPTHR11403. PTHR11403. 1 hit.
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_PROWI
AccessionPrimary (citable) accession number: Q37620
Entry history
Integrated into UniProtKB/Swiss-Prot: July 15, 1998
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programPlant Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families