Reviewed,
UniProtKB/Swiss-Prot Q37619 (NDUS2_PROWI)
Last modified
June 16, 2009.
Version 56.
History...
Clusters with 100%,
90%,
50% identity |
Documents (1) |
Third-party data |
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Names and origin
| Protein names | Recommended name: NADH-ubiquinone oxidoreductase 49 kDa subunit EC=1.6.5.3 EC=1.6.99.3 Alternative name(s): NADH dehydrogenase subunit 7 | ||
| Gene names |
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| Encoded on | Mitochondrion | ||
| Organism | Prototheca wickerhamii | ||
| Taxonomic identifier | 3111 [NCBI] | ||
| Taxonomic lineage | Eukaryota › Viridiplantae › Chlorophyta › Trebouxiophyceae › Chlorellales › Chlorellaceae › Prototheca |
Protein attributes
| Sequence length | 400 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity. Component of the iron-sulfur (IP) fragment of the enzyme. Component of the iron-sulfur (IP) fragment of the enzyme. |
| Catalytic activity | NADH + ubiquinone = NAD+ + ubiquinol. NADH + acceptor = NAD+ + reduced acceptor. |
| Subcellular location | |
| Sequence similarities | Belongs to the complex I 49 kDa subunit family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Electron transport Respiratory chain Transport |
| Cellular component | Mitochondrion |
| Ligand | NAD Ubiquinone |
| Molecular function | Oxidoreductase |
| Gene Ontology (GO) | |
| Biological process | electron transport chain Inferred from electronic annotation. Source: UniProtKB-KW transportInferred from electronic annotation. Source: UniProtKB-KW |
| Cellular component | mitochondrion Inferred from electronic annotation. Source: UniProtKB-SubCell respiratory chainInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | NAD or NADH binding Inferred from electronic annotation. Source: InterPro NADH dehydrogenase (ubiquinone) activityInferred from electronic annotation. Source: EC electron carrier activityInferred from electronic annotation. Source: InterPro quinone bindingInferred from electronic annotation. Source: InterPro |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 400 | 400 | NADH-ubiquinone oxidoreductase 49 kDa subunit | PRO_0000118591 | |||
Sequences
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References
| [1] | "Complete sequence of the mitochondrial DNA of the chlorophyte alga Prototheca wickerhamii. Gene content and genome organization." Wolff G., Plante I., Lang B.F., Kueck U., Burger G. J. Mol. Biol. 237:75-86(1994) [PubMed: 8133522] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]. Strain: 263-11. |
Cross-references
Sequence databases | |
|---|---|
| U02970 Genomic DNA. Translation: AAD12640.1. | |
| PIR | T11921. |
| RefSeq | NP_042252.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 802126. |
Enzyme and pathway databases | |
| BRENDA | 1.6.5.3. 191676. 1.6.99.3. 191676. |
Family and domain databases | |
| InterPro | IPR010219. NADH_DH_1_dsu. IPR001135. NADH_Q_OxRdtase_suD. IPR014029. NADH_UbQ_OxRdtase_su-49kDa_CS. [Graphical view] |
| Pfam | PF00346. Complex1_49kDa. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR01962. NuoD. 1 hit. |
| PROSITE | PS00535. COMPLEX1_49K. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | NDUS2_PROWI | ||||||||
| Accession | Primary (citable) accession number: Q37619 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | PPAP (Plant Proteome Annotation Project) | ||||||||

Clusters with


