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Q37383

- NDUS3_ACACA

UniProt

Q37383 - NDUS3_ACACA

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Protein

NADH-ubiquinone oxidoreductase subunit 9

Gene

NAD9

Organism
Acanthamoeba castellanii (Amoeba)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).By similarity

Catalytic activityi

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).
NADH + acceptor = NAD+ + reduced acceptor.

GO - Molecular functioni

  1. NADH dehydrogenase (ubiquinone) activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Biological processi

Electron transport, Respiratory chain, Transport

Keywords - Ligandi

NAD, Ubiquinone

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-ubiquinone oxidoreductase subunit 9 (EC:1.6.5.3, EC:1.6.99.3)
Gene namesi
Name:NAD9
Encoded oniMitochondrion
OrganismiAcanthamoeba castellanii (Amoeba)
Taxonomic identifieri5755 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaDiscoseaLongamoebiaCentramoebidaAcanthamoebidaeAcanthamoeba

Subcellular locationi

GO - Cellular componenti

  1. mitochondrial inner membrane Source: UniProtKB-KW
  2. respiratory chain Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 195195NADH-ubiquinone oxidoreductase subunit 9PRO_0000118644Add
BLAST

Interactioni

Subunit structurei

Complex I is composed of about 30 different subunits.

Structurei

3D structure databases

ProteinModelPortaliQ37383.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I 30 kDa subunit family.Curated

Family and domain databases

HAMAPiMF_01357. NDH1_NuoC.
InterProiIPR010218. NADH_DH_suC.
IPR001268. NADH_UbQ_OxRdtase_30kDa_su.
IPR020396. NADH_UbQ_OxRdtase_CS.
[Graphical view]
PfamiPF00329. Complex1_30kDa. 1 hit.
[Graphical view]
ProDomiPD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsiTIGR01961. NuoC_fam. 1 hit.
PROSITEiPS00542. COMPLEX1_30K. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q37383-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MGLNFFMSRK IYYIKLLTGL YKKFIKALIV KKNESNNAYL LVETANFYNL
60 70 80 90 100
VFSLQRSSLT QFKVLNDVCI VDYPEKIDRF ELSYNLSSIK YNFRIFIKTY
110 120 130 140 150
TSAYVPSIST LFNSANWIER ECWDMFGVFF TNHPDLRRIL TDYGFEGFPL
160 170 180 190
RKDFPLTGYI EIRYDDEKAN IVYEPLELSQ EYRLFNFTSP WEKIK
Length:195
Mass (Da):23,349
Last modified:November 1, 1996 - v1
Checksum:i449A900545A0F073
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U12386 Genomic DNA. Translation: AAD11853.1.
PIRiS53861.
RefSeqiNP_042560.1. NC_001637.1.

Genome annotation databases

GeneIDi1734055.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
U12386 Genomic DNA. Translation: AAD11853.1 .
PIRi S53861.
RefSeqi NP_042560.1. NC_001637.1.

3D structure databases

ProteinModelPortali Q37383.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 1734055.

Family and domain databases

HAMAPi MF_01357. NDH1_NuoC.
InterProi IPR010218. NADH_DH_suC.
IPR001268. NADH_UbQ_OxRdtase_30kDa_su.
IPR020396. NADH_UbQ_OxRdtase_CS.
[Graphical view ]
Pfami PF00329. Complex1_30kDa. 1 hit.
[Graphical view ]
ProDomi PD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit.
[Graphical view ] [Entries sharing at least one domain ]
TIGRFAMsi TIGR01961. NuoC_fam. 1 hit.
PROSITEi PS00542. COMPLEX1_30K. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The mitochondrial DNA of the amoeboid protozoon, Acanthamoeba castellanii: complete sequence, gene content and genome organization."
    Burger G., Plante I., Lonergan K.M., Gray M.W.
    J. Mol. Biol. 245:522-537(1995) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: ATCC 30010 / Neff.

Entry informationi

Entry nameiNDUS3_ACACA
AccessioniPrimary (citable) accession number: Q37383
Entry historyi
Integrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3