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Q37383

- NDUS3_ACACA

UniProt

Q37383 - NDUS3_ACACA

Protein

NADH-ubiquinone oxidoreductase subunit 9

Gene

NAD9

Organism
Acanthamoeba castellanii (Amoeba)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 73 (01 Oct 2014)
      Sequence version 1 (01 Nov 1996)
      Previous versions | rss
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    Functioni

    Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone By similarity.By similarity

    Catalytic activityi

    NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).
    NADH + acceptor = NAD+ + reduced acceptor.

    GO - Molecular functioni

    1. NADH dehydrogenase (ubiquinone) activity Source: UniProtKB-EC

    Keywords - Molecular functioni

    Oxidoreductase

    Keywords - Biological processi

    Electron transport, Respiratory chain, Transport

    Keywords - Ligandi

    NAD, Ubiquinone

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    NADH-ubiquinone oxidoreductase subunit 9 (EC:1.6.5.3, EC:1.6.99.3)
    Gene namesi
    Name:NAD9
    Encoded oniMitochondrion
    OrganismiAcanthamoeba castellanii (Amoeba)
    Taxonomic identifieri5755 [NCBI]
    Taxonomic lineageiEukaryotaAmoebozoaDiscoseaLongamoebiaCentramoebidaAcanthamoebidaeAcanthamoeba

    Subcellular locationi

    GO - Cellular componenti

    1. mitochondrial inner membrane Source: UniProtKB-SubCell
    2. respiratory chain Source: UniProtKB-KW

    Keywords - Cellular componenti

    Membrane, Mitochondrion, Mitochondrion inner membrane

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 195195NADH-ubiquinone oxidoreductase subunit 9PRO_0000118644Add
    BLAST

    Interactioni

    Subunit structurei

    Complex I is composed of about 30 different subunits.

    Structurei

    3D structure databases

    ProteinModelPortaliQ37383.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the complex I 30 kDa subunit family.Curated

    Family and domain databases

    HAMAPiMF_01357. NDH1_NuoC.
    InterProiIPR010218. NADH_DH_suC.
    IPR001268. NADH_UbQ_OxRdtase_30kDa_su.
    IPR020396. NADH_UbQ_OxRdtase_CS.
    [Graphical view]
    PfamiPF00329. Complex1_30kDa. 1 hit.
    [Graphical view]
    ProDomiPD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit.
    [Graphical view] [Entries sharing at least one domain]
    TIGRFAMsiTIGR01961. NuoC_fam. 1 hit.
    PROSITEiPS00542. COMPLEX1_30K. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q37383-1 [UniParc]FASTAAdd to Basket

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    MGLNFFMSRK IYYIKLLTGL YKKFIKALIV KKNESNNAYL LVETANFYNL    50
    VFSLQRSSLT QFKVLNDVCI VDYPEKIDRF ELSYNLSSIK YNFRIFIKTY 100
    TSAYVPSIST LFNSANWIER ECWDMFGVFF TNHPDLRRIL TDYGFEGFPL 150
    RKDFPLTGYI EIRYDDEKAN IVYEPLELSQ EYRLFNFTSP WEKIK 195
    Length:195
    Mass (Da):23,349
    Last modified:November 1, 1996 - v1
    Checksum:i449A900545A0F073
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U12386 Genomic DNA. Translation: AAD11853.1.
    PIRiS53861.
    RefSeqiNP_042560.1. NC_001637.1.

    Genome annotation databases

    GeneIDi1734055.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    U12386 Genomic DNA. Translation: AAD11853.1 .
    PIRi S53861.
    RefSeqi NP_042560.1. NC_001637.1.

    3D structure databases

    ProteinModelPortali Q37383.
    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 1734055.

    Family and domain databases

    HAMAPi MF_01357. NDH1_NuoC.
    InterProi IPR010218. NADH_DH_suC.
    IPR001268. NADH_UbQ_OxRdtase_30kDa_su.
    IPR020396. NADH_UbQ_OxRdtase_CS.
    [Graphical view ]
    Pfami PF00329. Complex1_30kDa. 1 hit.
    [Graphical view ]
    ProDomi PD001581. NADH_UbQ_OxRdtase_30kDa_su. 1 hit.
    [Graphical view ] [Entries sharing at least one domain ]
    TIGRFAMsi TIGR01961. NuoC_fam. 1 hit.
    PROSITEi PS00542. COMPLEX1_30K. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The mitochondrial DNA of the amoeboid protozoon, Acanthamoeba castellanii: complete sequence, gene content and genome organization."
      Burger G., Plante I., Lonergan K.M., Gray M.W.
      J. Mol. Biol. 245:522-537(1995) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
      Strain: ATCC 30010 / Neff.

    Entry informationi

    Entry nameiNDUS3_ACACA
    AccessioniPrimary (citable) accession number: Q37383
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: December 15, 1998
    Last sequence update: November 1, 1996
    Last modified: October 1, 2014
    This is version 73 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)

    Miscellaneousi

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3