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Protein

NADH-ubiquinone oxidoreductase subunit 9

Gene

NAD9

Organism
Acanthamoeba castellanii (Amoeba)
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).By similarity

Catalytic activityi

NADH + ubiquinone + 5 H+(In) = NAD+ + ubiquinol + 4 H+(Out).
NADH + acceptor = NAD+ + reduced acceptor.

GO - Molecular functioni

Keywordsi

Molecular functionOxidoreductase
Biological processElectron transport, Respiratory chain, Transport
LigandNAD, Ubiquinone

Names & Taxonomyi

Protein namesi
Recommended name:
NADH-ubiquinone oxidoreductase subunit 9 (EC:1.6.5.3, EC:1.6.99.3)
Gene namesi
Name:NAD9
Encoded oniMitochondrion
OrganismiAcanthamoeba castellanii (Amoeba)
Taxonomic identifieri5755 [NCBI]
Taxonomic lineageiEukaryotaAmoebozoaDiscoseaLongamoebiaCentramoebidaAcanthamoebidaeAcanthamoeba

Subcellular locationi

GO - Cellular componenti

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001186441 – 195NADH-ubiquinone oxidoreductase subunit 9Add BLAST195

Interactioni

Subunit structurei

Complex I is composed of about 30 different subunits.

Structurei

3D structure databases

ProteinModelPortaliQ37383
SMRiQ37383
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the complex I 30 kDa subunit family.Curated

Family and domain databases

Gene3Di3.30.460.80, 1 hit
HAMAPiMF_01357 NDH1_NuoC, 1 hit
InterProiView protein in InterPro
IPR010218 NADH_DH_suC
IPR037232 NADH_quin_OxRdtase_su_C/D-like
IPR001268 NADH_UbQ_OxRdtase_30kDa_su
IPR020396 NADH_UbQ_OxRdtase_CS
PfamiView protein in Pfam
PF00329 Complex1_30kDa, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD001581 NADH_UbQ_OxRdtase_30kDa_su, 1 hit
SUPFAMiSSF143243 SSF143243, 1 hit
TIGRFAMsiTIGR01961 NuoC_fam, 1 hit
PROSITEiView protein in PROSITE
PS00542 COMPLEX1_30K, 1 hit

Sequencei

Sequence statusi: Complete.

Q37383-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGLNFFMSRK IYYIKLLTGL YKKFIKALIV KKNESNNAYL LVETANFYNL
60 70 80 90 100
VFSLQRSSLT QFKVLNDVCI VDYPEKIDRF ELSYNLSSIK YNFRIFIKTY
110 120 130 140 150
TSAYVPSIST LFNSANWIER ECWDMFGVFF TNHPDLRRIL TDYGFEGFPL
160 170 180 190
RKDFPLTGYI EIRYDDEKAN IVYEPLELSQ EYRLFNFTSP WEKIK
Length:195
Mass (Da):23,349
Last modified:November 1, 1996 - v1
Checksum:i449A900545A0F073
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U12386 Genomic DNA Translation: AAD11853.1
PIRiS53861
RefSeqiNP_042560.1, NC_001637.1

Genome annotation databases

GeneIDi1734055

Similar proteinsi

Entry informationi

Entry nameiNDUS3_ACACA
AccessioniPrimary (citable) accession number: Q37383
Entry historyiIntegrated into UniProtKB/Swiss-Prot: December 15, 1998
Last sequence update: November 1, 1996
Last modified: March 28, 2018
This is version 82 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)

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