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Q37355 (COX3_TRYBO) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 65. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Cytochrome c oxidase subunit 3

EC=1.9.3.1
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene names
Name:COIII
Encoded onMitochondrion
OrganismTrypanoplasma borreli
Taxonomic identifier5710 [NCBI]
Taxonomic lineageEukaryotaEuglenozoaKinetoplastidaBodonidaeTrypanoplasma

Protein attributes

Sequence length286 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activity

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

Subcellular location

Mitochondrion inner membrane; Multi-pass membrane protein By similarity.

Sequence similarities

Belongs to the cytochrome c oxidase subunit 3 family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 286286Cytochrome c oxidase subunit 3
PRO_0000183869

Regions

Transmembrane13 – 3321Helical; Potential
Transmembrane40 – 6021Helical; Potential
Transmembrane85 – 10521Helical; Potential
Transmembrane133 – 15321Helical; Potential
Transmembrane173 – 19523Helical; Potential
Transmembrane199 – 22123Helical; Potential
Transmembrane223 – 24321Helical; Potential
Transmembrane253 – 27321Helical; Potential

Sequences

Sequence LengthMass (Da)Tools
Q37355 [UniParc].

Last modified November 1, 1996. Version 1.
Checksum: 80C9A05526773808

FASTA28633,313
        10         20         30         40         50         60 
MYLFRIISLN LSGVFLFLSY TPLYITYLLG VVISSMMLTV GTFAITLDII LCILVVCFLI 

        70         80         90        100        110        120 
TTLLVIDSVL DSIRGLNSVG VLVRIIQYCF LWFVFSEFML FVVFFYTLYS ECLLINVEFT 

       130        140        150        160        170        180 
NIGCPVTTKY SNIILDLGYI FYWFLFDFFN IILNTVYLFI SGLCCNNVLS SILCREYLLS 

       190        200        210        220        230        240 
KIILGSSIFL GLLFIWNQVW EFNILIITLS VNIFCTILFS IDTLHFMHVL VGIVFMIISI 

       250        260        270        280 
FNIQSKKIGD IRIVLIVCII FYWHFVDIVW FFLLRFIYLD TLMVLK 

« Hide

References

[1]"RNA editing and mitochondrial genomic organization in the cryptobiid kinetoplastid protozoan Trypanoplasma borreli."
Maslov D.A., Simpson L.
Mol. Cell. Biol. 14:8174-8182(1994) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
Strain: PG-JH.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
U14181 Genomic DNA. Translation: AAA65016.1.

3D structure databases

ProteinModelPortalQ37355.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Family and domain databases

Gene3D1.20.120.80. 1 hit.
InterProIPR000298. Cyt_c_oxidase_su3.
IPR013833. Cyt_c_oxidase_su3_a-hlx.
[Graphical view]
PfamPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMSSF81452. SSF81452. 1 hit.
PROSITEPS50253. COX3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameCOX3_TRYBO
AccessionPrimary (citable) accession number: Q37355
Entry history
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: April 16, 2014
This is version 65 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)

Relevant documents

SIMILARITY comments

Index of protein domains and families