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Q37355

- COX3_TRYBO

UniProt

Q37355 - COX3_TRYBO

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Protein

Cytochrome c oxidase subunit 3

Gene

COIII

Organism
Trypanoplasma borreli
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi

Functioni

Subunits I, II and III form the functional core of the enzyme complex.

Catalytic activityi

4 ferrocytochrome c + O2 + 4 H+ = 4 ferricytochrome c + 2 H2O.

GO - Molecular functioni

  1. cytochrome-c oxidase activity Source: UniProtKB-EC

GO - Biological processi

  1. respiratory electron transport chain Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Names & Taxonomyi

Protein namesi
Recommended name:
Cytochrome c oxidase subunit 3 (EC:1.9.3.1)
Alternative name(s):
Cytochrome c oxidase polypeptide III
Gene namesi
Name:COIII
Encoded oniMitochondrion
OrganismiTrypanoplasma borreli
Taxonomic identifieri5710 [NCBI]
Taxonomic lineageiEukaryotaEuglenozoaKinetoplastidaBodonidaeTrypanoplasma

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei13 – 3321HelicalSequence AnalysisAdd
BLAST
Transmembranei40 – 6021HelicalSequence AnalysisAdd
BLAST
Transmembranei85 – 10521HelicalSequence AnalysisAdd
BLAST
Transmembranei133 – 15321HelicalSequence AnalysisAdd
BLAST
Transmembranei173 – 19523HelicalSequence AnalysisAdd
BLAST
Transmembranei199 – 22123HelicalSequence AnalysisAdd
BLAST
Transmembranei223 – 24321HelicalSequence AnalysisAdd
BLAST
Transmembranei253 – 27321HelicalSequence AnalysisAdd
BLAST

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
  2. mitochondrial inner membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion, Mitochondrion inner membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 286286Cytochrome c oxidase subunit 3PRO_0000183869Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ37355.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Family and domain databases

Gene3Di1.20.120.80. 1 hit.
InterProiIPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view]
PfamiPF00510. COX3. 1 hit.
[Graphical view]
SUPFAMiSSF81452. SSF81452. 1 hit.
PROSITEiPS50253. COX3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q37355-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MYLFRIISLN LSGVFLFLSY TPLYITYLLG VVISSMMLTV GTFAITLDII
60 70 80 90 100
LCILVVCFLI TTLLVIDSVL DSIRGLNSVG VLVRIIQYCF LWFVFSEFML
110 120 130 140 150
FVVFFYTLYS ECLLINVEFT NIGCPVTTKY SNIILDLGYI FYWFLFDFFN
160 170 180 190 200
IILNTVYLFI SGLCCNNVLS SILCREYLLS KIILGSSIFL GLLFIWNQVW
210 220 230 240 250
EFNILIITLS VNIFCTILFS IDTLHFMHVL VGIVFMIISI FNIQSKKIGD
260 270 280
IRIVLIVCII FYWHFVDIVW FFLLRFIYLD TLMVLK
Length:286
Mass (Da):33,313
Last modified:November 1, 1996 - v1
Checksum:i80C9A05526773808
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14181 Genomic DNA. Translation: AAA65016.1.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
U14181 Genomic DNA. Translation: AAA65016.1 .

3D structure databases

ProteinModelPortali Q37355.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Family and domain databases

Gene3Di 1.20.120.80. 1 hit.
InterProi IPR013833. Cyt_c_oxidase_su3_a-hlx.
IPR000298. Cyt_c_oxidase_su3_dom.
[Graphical view ]
Pfami PF00510. COX3. 1 hit.
[Graphical view ]
SUPFAMi SSF81452. SSF81452. 1 hit.
PROSITEi PS50253. COX3. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "RNA editing and mitochondrial genomic organization in the cryptobiid kinetoplastid protozoan Trypanoplasma borreli."
    Maslov D.A., Simpson L.
    Mol. Cell. Biol. 14:8174-8182(1994) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA].
    Strain: PG-JH.

Entry informationi

Entry nameiCOX3_TRYBO
AccessioniPrimary (citable) accession number: Q37355
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 1, 1997
Last sequence update: November 1, 1996
Last modified: October 29, 2014
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)

Miscellaneousi

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3